Navigation Links
Lexicon Presents Positive Outcome in IBS Patients Treated With LX1031 and Data Supporting Mechanism of Action
Date:5/5/2010

THE WOODLANDS, Texas, May 5 /PRNewswire-FirstCall/ -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX), a biopharmaceutical company focused on discovering and developing breakthrough treatments for human disease, presented results from its positive Phase 2 clinical study with LX1031 in patients with non-constipating irritable bowel syndrome (IBS) at Digestive Disease Week (DDW) 2010 in New Orleans, Louisiana.

LX1031 is an oral, serotonin synthesis inhibitor that acts locally in the gastrointestinal tract targeting tryptophan hydroxylase (TPH), an enzyme necessary for the production of serotonin. LX1031 is the first TPH inhibitor to be evaluated in human clinical trials for the treatment of IBS.  Results from the randomized, placebo-controlled study of 155 patients with non-constipating IBS showed that patients who received LX1031 (1,000 mg four times a day) for 28 days experienced significant improvement (p<0.05) in global assessment of relief of IBS pain and discomfort over the four-week dosing
'/>"/>

SOURCE Lexicon Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Lexicon to Provide Clinical Pipeline Update and Report First Quarter 2010 Financial Results
2. Lexicon to Present at BIO International Convention
3. Lexicon to Present Phase 2 Clinical Data for IBS Drug Candidate at Digestive Disease Week
4. Lexicon Announces Proposed $95 Million Common Stock Offering
5. Lexicon to Report Fourth Quarter and Year End 2009 Financial Results on February 23, 2010
6. Lexicon Pharmaceuticals to Present at the 12th Annual BIO CEO & Investor Conference
7. Lexicon to Host Conference Call and Webcast to Review Top-Line Phase 2 Results From Diabetes Trial
8. Lexicon to Present Positive Top-Line Phase 2 Results for LX1031 in Non-Constipating Irritable Bowel Syndrome at GASTRO 2009
9. Lexicon Announces Positive Phase 2 Results of LX1031 in Non-Constipating Irritable Bowel Syndrome
10. Lexicon Announces Completion of Public Offering of Common Stock
11. Lexicon Announces Pricing of Common Stock in Public Offering
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/26/2014)... , Nov. 26, 2014 / -- China Nepstar Chain Drugstore Ltd. (NYSE: ... leading retail drugstore chain in China ... today announced the appointment of Ms. Rebecca Yingnan ... immediately. Ms.Zhang has over 20 years ... in March 1999. Prior to Ms. Zhang,s appointment as ...
(Date:11/24/2014)... 2014  Arena Pharmaceuticals, Inc. (NASDAQ: ARNA ) ... overview and update at the Piper Jaffray 26 th ... a.m. Eastern Time (5:30 a.m. Pacific Time), at The New ... A live audio webcast of the presentation will ... at www.arenapharm.com . A replay of the presentation will ...
(Date:11/24/2014)... Luoxis Diagnostics, Inc., a subsidiary of ... the presentation of three clinical and preclinical studies ... applicable and robust research tool capable of measuring ... to injury, illness, or stress.  In all three ... academic and pharmaceutical research partners, RedoxSYS was able ...
Breaking Medicine Technology:China Nepstar Chain Drugstore Appoints Ms. Rebecca Yingnan Zhang as Chief Operating Officer 2China Nepstar Chain Drugstore Appoints Ms. Rebecca Yingnan Zhang as Chief Operating Officer 3Arena Pharmaceuticals to Present at Piper Jaffray 26th Annual Healthcare Conference 2Arena Pharmaceuticals to Present at Piper Jaffray 26th Annual Healthcare Conference 3Luoxis Announces Presentation of Multiple Studies Validating RedoxSYS as a Rapid and Non-invasive Means of Assessing Oxidative Stress 2Luoxis Announces Presentation of Multiple Studies Validating RedoxSYS as a Rapid and Non-invasive Means of Assessing Oxidative Stress 3Luoxis Announces Presentation of Multiple Studies Validating RedoxSYS as a Rapid and Non-invasive Means of Assessing Oxidative Stress 4Luoxis Announces Presentation of Multiple Studies Validating RedoxSYS as a Rapid and Non-invasive Means of Assessing Oxidative Stress 5
... 150 lung transplant patients demonstrates potential to improve ... management of risk ... of data,collected from 170 patients receiving lung transplantation at the,University ... of cell-mediated immunity (CMI), when combined with,microbial analysis of bronchoalveolar ...
... (Nasdaq: MNKD ) released the following statement ... over the course of Exubera,s clinical,trial program, 6 ... lung,cancer, although Pfizer concluded that there were too ... to Exubera. According to,Pfizer,s "Dear Doctor" letter, Exubera ...
Cached Medicine Technology:Prospective Microbial Analysis of Bronchoalveolar Lavage Fluids with Immune Function Testing Can Distinguish Between Fungal Colonization and Fungal Disease In Lung Transplant Recipients 2Prospective Microbial Analysis of Bronchoalveolar Lavage Fluids with Immune Function Testing Can Distinguish Between Fungal Colonization and Fungal Disease In Lung Transplant Recipients 3MannKind Addresses Pfizer's Announcement Regarding Exubera 2MannKind Addresses Pfizer's Announcement Regarding Exubera 3
(Date:11/26/2014)... CA (PRWEB) November 26, 2014 Gone are ... after cheap deals on Black Friday, which signifies the beginning ... clicking items into their shopping carts in the comfort of ... , This Friday is going to be an ... a day, with an estimated $2.48 billion in revenue for ...
(Date:11/26/2014)... November 26, 2014 With Thousand Oaks ... dollars, the prosthodontists at the Anacapa Dental Art Institute in ... procedures can be daunting for some. , That is why ... procedures they offer. , “No dentist wants cost to come ... of teeth,” said Dr. Mamaly Reshad, partner in the Anacapa ...
(Date:11/26/2014)... (PRWEB) November 26, 2014 Anthropologists ... effectiveness in containing and stopping Ebola, improve international ... in healthcare systems in West Africa. , ... to Stop Ebola: Anthropologists Offer Insights,” will be ... the American Anthropological Association (AAA), Fri., Dec. 5, ...
(Date:11/26/2014)... 26, 2014 Louisiana Back Institute, ... specialists in minimally invasive spine surgery, announces today ... the rapidly growing provider network of orthopedic spine ... coincides with the network’s continuing success providing the ... Louisiana residents who are suffering from orthopedic spine ...
(Date:11/26/2014)... TUESDAY, Nov. 25, 2014 (HealthDay News) -- Vultures have ... bacteria they ingest when eating dead animals, researchers report. ... bacteria found on the faces and in the guts ... United States. On average, the faces of the vultures ... with 76 in their guts, the study found. ...
Breaking Medicine News(10 mins):Health News:2014 Best Friday Deals Revealed by Top10InAction 2Health News:Anacapa Dental Art Institute Doctors Offers 6 Tips on How to Pay for Cosmetic, Restorative and Implant Dentistry 2Health News:Anacapa Dental Art Institute Doctors Offers 6 Tips on How to Pay for Cosmetic, Restorative and Implant Dentistry 3Health News:Anacapa Dental Art Institute Doctors Offers 6 Tips on How to Pay for Cosmetic, Restorative and Implant Dentistry 4Health News:Anacapa Dental Art Institute Doctors Offers 6 Tips on How to Pay for Cosmetic, Restorative and Implant Dentistry 5Health News:Anthropologists Release Recommendations, Better Practices to Contain Ebola 2Health News:Anthropologists Release Recommendations, Better Practices to Contain Ebola 3Health News:Louisiana Back Institute Welcomes Dr. K. Samer Shamieh into Medical Provider Network 2
... , , MINNEAPOLIS, ... for people with disabilities, is seeking applications for the annual Judd ... in 1992, the Jacobson Award recognizes the pursuit or achievement of ... or sensory impairment. The award recipient will be honored at an ...
... manufacturers say, , WEDNESDAY, July 22 (HealthDay News) -- ... in the world,s first H1N1 swine flu vaccine trials, ... the virus that has so far killed more than ... with 300 participants, while Melbourne,s CSL has 240 people ...
... July 22 When a dog or cat bites, an infection can ... likely to become infected are those on the face and hands or ... Dr. Kate Stenske, a clinical assistant professor at Kansas State University,s College ... with soap and water, and then call your physician right away." , ...
... FRANKLIN, Tenn., July 22 MedIn ... compensation managed care services provider, and myMa ... pharmacy management solutions for workers, compensation claims, announced a new ... an advanced technology platform. myMatrixx will enable MedInsights to ...
... & Lamont 2009 Growth Stock Conference , , ... , , ACCESS PHARMACEUTICALS, INC. ... Davis, President & CEO, will present at the Jesup & Lamont 2009 Growth ... at 10:45 am EDT. The presentation will occur live and will be ...
... , , , ... Board: ACCP) announced today that Jeffrey B. Davis, President & CEO, ... the LifeTech Capital Group on Thursday, July 30, 2009 at 10:45 am EDT. ... Astoria Boca Beach Club in Boca Raton, Florida. , , ...
Cached Medicine News:Health News:Courage Center Seeks Applications for 2009 Judd Jacobson Memorial Award 2Health News:World's 1st Swine Flu Vaccine Trials Start in Australia 2Health News:World's 1st Swine Flu Vaccine Trials Start in Australia 3Health News:World's 1st Swine Flu Vaccine Trials Start in Australia 4Health News:World's 1st Swine Flu Vaccine Trials Start in Australia 5Health News:World's 1st Swine Flu Vaccine Trials Start in Australia 6Health News:World's 1st Swine Flu Vaccine Trials Start in Australia 7Health News:World's 1st Swine Flu Vaccine Trials Start in Australia 8Health News:World's 1st Swine Flu Vaccine Trials Start in Australia 9Health News:World's 1st Swine Flu Vaccine Trials Start in Australia 10Health News:World's 1st Swine Flu Vaccine Trials Start in Australia 11Health News:World's 1st Swine Flu Vaccine Trials Start in Australia 12Health News:Pet Bite Injuries: K-State Veterinarian Shares Tips to Minimize Risk of Bites and Bite-Related Infections 2Health News:MedInsights Partners With myMatrixx(TM) for Workers' Compensation Pharmacy Benefit Management 2Health News:UPDATE: Access Pharmaceuticals to Present at Jesup & Lamont 2009 Growth Stock Conference 2Health News:Access Pharmaceuticals to Present at Jesup & Lamont 2009 Growth Stock Conference 2
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... national reference laboratory and a worldwide leader ... offers an extensive test menu of highly ... and anatomic pathology. Owned by the University ... than half of the nation's university teaching ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: