Navigation Links
Lexicon Presents Data at the American Diabetes Association Meeting On Blood Pressure Reduction and Weight Loss In Clinical Trial of LX4211
Date:6/24/2013

THE WOODLANDS, Texas, June 24, 2013 /PRNewswire/ -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX), a biopharmaceutical company focused on discovering breakthrough treatments for human disease, delivered two oral and two poster presentations on LX4211 at the 73rd Scientific Sessions of the American Diabetes Association (ADA) in Chicago, on June 23, 2013.

Pablo Lapuerta, M.D., Lexicon's executive vice president, clinical development and chief medical officer, delivered an oral presentation titled "LX4211, a Dual Inhibitor of Sodium Glucose Transporters SGLT1 and SGLT2, Reduces Blood Pressure in Patients with Type 2 Diabetes."  This presentation highlighted the reductions in blood pressure by LX4211 for subgroups with varying blood pressures at baseline in a 12-week dose-ranging Phase 2b study of 299 patients with type 2 diabetes. Patients with high baseline systolic blood pressure (>130 mmHg) dosed with LX4211 experienced an average of 14 mmHg reduction in systolic blood pressure when compared to placebo (p=0.002). In contrast, patients with normal systolic blood pressure at baseline (<130 mmHg) experienced an average of 1 mmHg reduction (p=0.6). Systolic blood pressure readings below 100 mmHg, as well as orthostatic systolic blood pressure changes (changes due to a shift in position such as seated-to-standing and supine-to-standing), were no different between patients treated with LX4211 and those on placebo.

"This new analysis of data from the trial shows that LX4211 lowers blood pressure to a greater extent in those patients who are in the greatest need of treatment, that is, those patients with hypertension," said Dr. Lapuerta. "Furthermore, patients with normal blood pressure showed little or no change on LX4211
'/>"/>

SOURCE Lexicon Pharmaceuticals, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Lexicon Presents Preclinical Data On LX2761, a New Clinical Candidate for Diabetes Designed to Reduce Glucose Absorption From Gastrointestinal Tract
2. Lexicon To Present At The Goldman Sachs Global Healthcare Conference
3. Lexicon To Present At The Jefferies Global Healthcare Conference
4. Lexicon To Present At The Bank of America Merrill Lynch Healthcare Conference
5. Lexicon Pharmaceuticals Provides Clinical Pipeline Update and Reports 2013 First Quarter Financial Results
6. Lexicon Advances LX4211 In Type 1 Diabetes Phase 2 Trial
7. Lexicon to Report First Quarter Financial Results on May 10, 2013
8. Lexicon To Present At The Needham Healthcare Conference
9. Lexicon Pharmaceuticals Provides Clinical Pipeline Update And Reports 2012 Fourth Quarter And Full Year Financial Results
10. Lexicon To Present At The BIO CEO & Investor Conference
11. Lexicon Pharmaceuticals To Present At The Piper Jaffray Annual Healthcare Conference
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/20/2014)... , Oct. 20, 2014  AnaptysBio, Inc., ... therapeutic antibodies, today announced the appointment of ... Dr. Londei will lead the preclinical and clinical ... "We are pleased to welcome Dr. Londei ... Suria , President and Chief Executive Officer of ...
(Date:10/20/2014)... 20, 2014   Mary,s Medicinals today announced ... a 4-Star Sponsor of Operation Grow4Vets , a ... products, programs and services to assist them in living ... Key Facts: , An ever-increasing number of ... and effective treatment for pain, Post-traumatic Stress Disorder (PTSD) ...
(Date:10/19/2014)... SEATTLE, Wash. , Oct. 20, 2014 ... today that it will report its third quarter 2014 ... close of the U.S. financial markets. Following the announcement, ... conference call to discuss the results and provide a ... PDT). Access to the event can be obtained as ...
Breaking Medicine Technology:AnaptysBio Appoints Dr. Marco Londei to Newly Created Chief Development Officer Position Clinical Immunologist to Lead AnaptysBio's Pipeline Advancement 2Mary's Medicinals Announces 4-Star Sponsorship of Operation Grow4Vets 2Mary's Medicinals Announces 4-Star Sponsorship of Operation Grow4Vets 3CTI BioPharma to Report Third Quarter 2014 Financial Results on October 29, 2014 2
(Date:10/20/2014)... Pittsburgh, PA (PRWEB) October 20, 2014 ... new, minimally-invasive procedure that enables physicians to repair a ... , The MitraClip system, developed by ... regurgitation (MR), a progressive and life-threatening condition in which ... allowing blood to flow backward from the heart’s left ...
(Date:10/20/2014)... 2014 T.E.N., a technology and ... today that William H. Murray, renowned author and ... Luminary Leadership Award winner. Presented annually, the ISE® ... outstanding leader and industry practitioner for his or ... the information security industry. , Formerly with IBM, ...
(Date:10/20/2014)... 2014 My Clients Plus ( http://www.MyClientsPlus.com ... The new module enables easy administration and routing ... quality care. , This application allows users such as ... attach a to-do item to a specific client, categorize ... up reoccurring reminders for follow-ups. It's designed to ...
(Date:10/20/2014)... (PRWEB) October 20, 2014 Rockynol ... Living Center on Oct. 14. The $11 million project ... services, and a cooked-to-order kitchen with full-service restaurant style ... premier choice for first class Assisted Living apartments,” said ... residents deserve the highest quality of care and this ...
(Date:10/20/2014)... Final Cut Pro X Plugin developers from Pixel Film ... FCPX filmmakers . , “Fun, cool, and simple are ... Says Christina Austin, CEO of Pixel Film Studios. “It has ... comes with all the tools needed for a full ... added style, a title screen for an introduction, two lower ...
Breaking Medicine News(10 mins):Health News:Allegheny General Hospital Introduces New, Beating-Heart Procedure for Mitral Valve Repair 2Health News:Allegheny General Hospital Introduces New, Beating-Heart Procedure for Mitral Valve Repair 3Health News:Bill Murray named 2014 ISE® Luminary Leadership Award Winner 2Health News:Bill Murray named 2014 ISE® Luminary Leadership Award Winner 3Health News:Bill Murray named 2014 ISE® Luminary Leadership Award Winner 4Health News:My Clients Plus Announces New Workflow Management Software 2Health News:Rockynol Retirement Community Expands Assisted Living Center 2Health News:Today Pixel Film Studios Announced the Release of the Citrus theme for Final Cut Pro X 2
... ... Pole Fitness, Women’s Answer to a Male Dominated Gym scene. Embody Pole gives the women ... ... notion of physical fitness were completely male-centered. Where do women go when they want to ...
... for spike between 2008 and 2009, analysis finds , ... injuries appear to be on the rise, warns the ... sports and baseball/softball are the main culprits. , The ... trends as they transpired between 2008 and 2009, based ...
... disease remission in patients with rheumatoid arthritis (RA) ... including work productivity and quality of life according ... Annual Congress of the European League Against Rheumatism ... reported in addition to improvements in measures of ...
... drinkers were 39% less likely to get these malignancies ... help protect against head and neck cancers, a new ... the International Head and Neck Cancer Epidemiology consortium. They ... a day) were 39 percent less likely to develop ...
... cost of brain-tumor surgery might both be reduced if surgery ... procedure, according to a new study conducted at The Ohio ... Richard J. Solove Research Institute. The study, published online June ... outcomes of 39 patients treated for glioma, a type of ...
... being a good dad, expert suggests , FRIDAY, June 18 ... new ties and other tokens of gratitude, they might think ... a promise that they,ll watch their health, suggests a family ... die younger than women and are more likely to die ...
Cached Medicine News:Health News:&#8220;Embody Pole Fitness&#8221; Puts a Sexy Spin on Fitness in the Inland Empire 2Health News:Bump in Head Injury Numbers Linked to Summer Play 2Health News:Targeting disease remission has socio-economic benefits over low disease activity 2Health News:Targeting disease remission has socio-economic benefits over low disease activity 3Health News:Awake sedation for brain surgery may shorten hospital stay 2Health News:On Father's Day, Give Dad Gift of Health 2
Heine Beta 200 Streak Retinoscope 2.5v...
Keeler Professional Combi Retinoscope with new slimline handle and lithium or dry cell option....
System, English (Continental cord), 230 VAC....
Micro-mini fiber optic light....
Medicine Products: