Navigation Links
Lexicon Pharmaceuticals Reports on Clinical Program Status and 2011 Third Quarter Results
Date:11/1/2011

study published in the August 2011 issue of the journal Gastroenterology showed that LX1031 was well tolerated and provided clinical benefit to patients with non-constipating IBS, showing improvements in a global assessment of adequate relief from IBS pain and discomfort and in stool consistency, with symptom relief correlating with reductions in the 5-HIAA biomarker.  Like LX1031, LX1033 acts locally in the gastrointestinal tract to reduce serotonin production by inhibiting tryptophan hydroxylase, a key enzyme in the biosynthesis of serotonin.  
  • LX2931:  Lexicon initiated a dose-ranging study to explore higher doses of LX2931 in rheumatoid arthritis patients.  Previously-reported Phase 2a results of LX2931, an inhibitor of sphingosine-1-phosphate lyase, demonstrated a favorable safety profile at all doses tested and suggest that rheumatoid arthritis patients treated with 150 mg of LX2931 once daily showed improvement in the primary efficacy endpoint of the study, the percentage of patients achieving an American College of Rheumatology 20 (ACR20) response at week 12.

  • Financial Results Revenues:  Lexicon's revenues for the three months ended September 30, 2011 decreased 55 percent to $0.4 million from $0.8 million for the corresponding period in 2010.  For the nine months ended September 30, 2011, revenues decreased 59 percent to $1.5 million from $3.7 million for the corresponding period in 2010.

    Research and Development Expenses:  Research and development expenses for the three months ended September 30, 2011 increased 4 percent to $19.7 million from $18.9 million for the corresponding period in 2010, primarily due to an increase in external preclinical and clinical research and development costs, offset by a decrease in personnel costs.  For the nine months ended September 30, 2011, research and develop
    '/>"/>

    SOURCE Lexicon Pharmaceuticals, Inc.
    Copyright©2010 PR Newswire.
    All rights reserved

    Page: 1 2 3 4 5 6 7 8

    Related medicine technology :

    1. Lexicon to Provide Clinical Pipeline Update and Report Third Quarter 2011 Financial Results
    2. Lexicon Presents LX4211 Clinical Data at European Association for the Study of Diabetes Annual Meeting
    3. Lexicon Pharmaceuticals to Present at Morgan Stanley Global Healthcare Conference
    4. Lexicon Pharmaceuticals to Present at Stifel Nicolaus Healthcare Conference
    5. Lexicon Pharmaceuticals to Present at the Wedbush 2011 Life Sciences Management Access Conference
    6. Lexicon Announces Publication of Results From the Phase 2 Trial of LX1031 in Patients With Irritable Bowel Syndrome in Journal of Gastroenterology
    7. Phase 2 Trial of Lexicons LX1032, Telotristat Etiprate, Shows Positive Results in Carcinoid Syndrome
    8. Lexicon Pharmaceuticals Reports on Clinical Program Status and 2011 Second Quarter Results
    9. Lexicons IBS Drug Candidate, LX1033, Successfully Completes Phase 1 Clinical Trial
    10. Lexicon Presents LX4211 Mechanism of Action Data at American Diabetes Association Meeting and Announces Commencement of Phase 2b Clinical Trial in Type 2 Diabetes
    11. Lexicon Pharmaceuticals Announces Webcast of 2011 Annual R&D Day
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    (Date:1/15/2014)... , Jan. 15, 2014  Manufacturers, suppliers ... technologies must be able to protect their ... (Logo: http://photos.prnewswire.com/prnh/20130716/CL46586LOGO ) ... of the Medical Device Industry, it steadfastly ... sectors of cases involving IP infringement. This ...
    (Date:1/15/2014)... R.I. , Jan. 15, 2014 MultiCell ... has filed a U.S. provisional patent application concerning composition ... formulations to achieve targeted tumor cell death.  ... very small noncoding double stranded RNA molecules (VSRNAs) which ... cells. VSRNAs are of molecular size less than 10 ...
    (Date:1/15/2014)... 15, 2014  According to Millennium Research Group ... intelligence, the United States ... markets will expand moderately through 2022, with embolization ... particular, increasing interest in drug-eluting beads (DEBs) and ... growth of these markets. The European ...
    Breaking Medicine Technology:Intellectual Property Insurance for Medical-related Products and Services 2MultiCell Technologies Files Patent Application Covering New Class of RNA Therapeutics 2MultiCell Technologies Files Patent Application Covering New Class of RNA Therapeutics 3US and European Transcatheter Embolization and Occlusion Device Market to Surpass $1.6 Billion by 2022 2US and European Transcatheter Embolization and Occlusion Device Market to Surpass $1.6 Billion by 2022 3
    ... Therapeutics (NYSE Amex: CXM ) today provided an ... Pharmaceuticals, business assets in connection with a proposed asset purchase ... on June 27, 2011, the completion of such an asset ... of the bankruptcy court.  In an effort to expedite the ...
    ... Corporation,s (NYSE: BSX ) Board of Directors ... up to $1.0 billion of its common stock and ... existing share repurchase program. "This repurchase program ... long-term business prospects, earnings growth potential and our ability ...
    Cached Medicine Technology:Cardium Reports on Transdel Transaction 2Cardium Reports on Transdel Transaction 3Cardium Reports on Transdel Transaction 4Boston Scientific Announces $1.0B Share Repurchase Program 2Boston Scientific Announces $1.0B Share Repurchase Program 3
    (Date:4/14/2014)... John DeLuca, PhD, and Yael Goverover, PhD, OT, have ... persons with multiple sclerosis (MS) perform everyday life tasks. ... Measure Everyday Life Functional Activity in Multiple Sclerosis" provides ... senior VP of Research & Training at Kessler Foundation. ... is a visiting scientist at Kessler Foundation. She was ...
    (Date:4/14/2014)... the answer to one open-ended question predicted the teenagers, offending ... think you,ll live?", According to the study, having little hope ... Piquero said the study found those who don,t view a ... rates and commit more serious offenses, while those who believe ... less., "In a lot of distressed communities and for a ...
    (Date:4/14/2014)... a molecule that is a probable driving force in ... an important target for colorectal cancer treatment and a ... microRNA-135b (miR-135b) in two animal models and human tumors ... and was led by researchers at The Ohio State ... Hospital and Richard J. Solove Research Institute (OSUCCC ...
    (Date:4/14/2014)... Depression can hit young fathers hard -- with symptoms increasing ... children,s lives, a new Northwestern Medicine study has found. , ... first five years of fatherhood for these young men, who ... whom lived in the same home as their children. The ... journal Pediatrics . , This study is the first ...
    (Date:4/14/2014)... WASHINGTON, April 14In dense, urban centers around the world, ... streets surrounded by tall buildings that block sunlight. And ... are jammed closer together, the darkness will only spread. ... developed a corrugated, translucent panel that redirects sunlight onto ... rooftops and hung over the edge at an angle, ...
    Breaking Medicine News(10 mins):Health News:UT Dallas study: Youth who fail to envision future commit more crimes 2Health News:Study identifies a likely key driver of colorectal cancer development and progression 2Health News:Young dads at high risk of depression, too 2Health News:Let the sun shine in: Redirecting sunlight to urban alleyways 2
    ... /PRNewswire/ -- Aesthetic Medical Educators ... medical professionals on Aesthetic Procedures over the past ... training include physicians, nurses, physician assistants and dentists, ... in his/her practice.These medical professionals have been trained ...
    ... Convene in Washington D.C. ... Pass Legislation that Will Protect the Public WASHINGTON, April ... of foodborne illness, including surviving family members of those ... Capitol to share their stories, meet with legislators and ...
    ... -- With the 2009 NBA playoff season ... public affairs television program that tells the compelling and ... and diabetes patient Dominique Wilkins. Sharing Miracles ... stations. A nine-time NBA all-star who spent the majority ...
    ... Controls Limit Vaccine SuppliesDALLAS, April 29 Fears of ... new vaccines, as well as meeting public demand for ... National Center for Policy Analysis. "We are facing ... six vaccines for common childhood illnesses," said NCPA Senior ...
    ... Executive Chairman & CEO Douglas MacLellan offers expert insight ... April 29 AMDL Inc. ... major operations in China, announced today its Executive Chairman ... featured in The Wall Street Transcript - ...
    ... appear to be safe, but more research needed ... shows promise in treating diabetic polyneuropathy, a disorder that ... years, a new study finds. , Researchers in Boston ... (VEGF) gene may help patients with diabetic polyneuropathy. The ...
    Cached Medicine News:Health News:Aesthetic Medical Educators Training Successfully Trains Over 2,000 Medical Professionals on Aesthetic Procedures 2Health News:Foodborne Illness Victims Mark President Obama's First 100 Days By Calling For Permanent Fix To Food Safety System 2Health News:Foodborne Illness Victims Mark President Obama's First 100 Days By Calling For Permanent Fix To Food Safety System 3Health News:'Sharing Miracles' Television Program to Feature NBA Hall-of-Famer, Scoring Champ Dominique Wilkins 2Health News:'Sharing Miracles' Television Program to Feature NBA Hall-of-Famer, Scoring Champ Dominique Wilkins 3Health News:'Sharing Miracles' Television Program to Feature NBA Hall-of-Famer, Scoring Champ Dominique Wilkins 4Health News:'Sharing Miracles' Television Program to Feature NBA Hall-of-Famer, Scoring Champ Dominique Wilkins 5Health News:'Sharing Miracles' Television Program to Feature NBA Hall-of-Famer, Scoring Champ Dominique Wilkins 6Health News:'Sharing Miracles' Television Program to Feature NBA Hall-of-Famer, Scoring Champ Dominique Wilkins 7Health News:'Sharing Miracles' Television Program to Feature NBA Hall-of-Famer, Scoring Champ Dominique Wilkins 8Health News:Swine Flu Outbreak Illustrates Problems in Vaccine Development 2Health News:Chinese Pharma Market Continues to Grow at a 5-7% Rate in 2009; AMDL Remains on Track to Meet FY09 Financial Targets 2Health News:Chinese Pharma Market Continues to Grow at a 5-7% Rate in 2009; AMDL Remains on Track to Meet FY09 Financial Targets 3Health News:Gene Therapy Improves Diabetic Neuropathy in Study 2
    ... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
    ... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
    ... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
    ... a national reference laboratory and a worldwide ... ARUP offers an extensive test menu of ... clinical and anatomic pathology. Owned by the ... more than half of the nation's university ...
    Medicine Products: