Navigation Links
Lexicon Pharmaceuticals Provides Clinical Pipeline Update And Reports 2012 Fourth Quarter And Full Year Financial Results
Date:2/21/2013

ions in body weight and blood pressure. In addition, Lexicon initiated a study in type 2 diabetes patients with renal impairment.
  • Telotristat etiprate (LX1032):  Lexicon initiated a pivotal Phase 3 clinical trial of telotristat etiprate, an inhibitor of tryptophan hydroxylase that reduces peripheral serotonin production without affecting brain serotonin levels. The Phase 3 registrational trial is a 12-week, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of telotristat etiprate as a new treatment for carcinoid syndrome that is refractory to current therapy.  The study is expected to enroll approximately 105 patients.  Lexicon reported data from an open-label Phase 2 trial in which telotristat etiprate showed evidence of clinical benefit across several endpoints in carcinoid syndrome patients. Benefits included reductions in bowel movement frequency, decreased urinary 5-HIAA (a biomarker of serotonin synthesis), and improvements in patient-reported relief of symptoms. Lexicon received Orphan Drug designation for telotristat etiprate from the U.S. Food and Drug Administration (FDA) for the treatment of carcinoid syndrome, having previously obtained Fast Track designation from the FDA and Orphan Drug designation from the European Medicines Agency (EMA). In addition to ongoing development in carcinoid syndrome, Lexicon also initiated a Phase 2 proof-of-concept study of telotristat etiprate in patients with ulcerative colitis.
  • LX1033: Lexicon initiated a Phase 2 clinical trial of LX1033, an inhibitor of tryptophan hydroxylase that acts locally in the gastrointestinal tract to reduce serotonin production, in patients with diarrhea-predominant IBS (IBS-d). The Phase 2 trial is a randomized, double-blind, placebo-controlled study designed to evaluate the safe
    '/>"/>

    • SOURCE Lexicon Pharmaceuticals, Inc.
    Copyright©2012 PR Newswire.
    All rights reserved

    0

    GOOD

    Page: 1 2 3 4 5 6 7

    Related medicine technology :

    1. Lexicon To Present At The BIO CEO & Investor Conference
    2. Lexicon Pharmaceuticals To Present At The Piper Jaffray Annual Healthcare Conference
    3. Lexicon Pharmaceuticals Reports on Clinical Program Status and 2012 Third Quarter Results
    4. Lexicon to Provide Third Quarter 2012 Financial Results
    5. Lexicon Pharmaceuticals To Present At The Stifel Nicolaus 2012 Healthcare Conference
    6. Lexicon Pharmaceuticals Reports Preliminary Results From Two Phase 1 Studies
    7. Lexicon Pharmaceuticals To Present At The Wedbush PacGrow 2012 Management Access Conference
    8. Lexicon Pharmaceuticals Reports On Clinical Program Status And 2012 Second Quarter Results
    9. Lexicon to Provide Second Quarter 2012 Financial Results
    10. Lexicon Announces Publication of Results of Two Studies of LX4211 in Patients with Type 2 Diabetes in the Journal Clinical Pharmacology & Therapeutics
    11. Lexicon Announces Positive Results of LX4211 Phase 2b Trial For Type 2 Diabetes
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    (Date:5/24/2013)...  Sinovac Biotech Ltd. (NASDAQ: SVA ... China , announced that Sinovac ... obtained the Certificate of Good Manufacturing Practices for ... and Food Administration (CFDA) for its proprietary vaccines, ... Changping filing and packaging facility. The GMP certificate ...
    (Date:5/23/2013)... y PARÍS, 24 de mayo de 2013 /PRNewswire/ ... destacado desarrollador y fabricante de herramientas de precisión ... y tratamiento de la enfermedad vascular periférica y ... ADVISE ( Ad enosine V asodilator ... II durante la sesión de ensayo clínico hot ...
    (Date:5/23/2013)... , May 23, 2013 Hearing health affects a ... younger, and remain socially and professionally engaged, he should address ... overriding message that the Better Hearing Institute (BHI) ... National Men,s Health Week , which leads up to ... runs from June 10 through June 16. ...
    Breaking Medicine Technology:Sinovac Beijing Obtains China GMP Certificate Under the New GMP Guidelines 2Sinovac Beijing Obtains China GMP Certificate Under the New GMP Guidelines 3Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 2Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 3Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 4Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 5Volcano anuncia los resultados preliminares del estudio ADVISE II y su inclusión en el ensayo SYNTAX2 6Men Who Want to Stay Active, Feel Younger, and Remain Socially and Professionally Engaged Should Address Hearing Loss, BHI Advises 2Men Who Want to Stay Active, Feel Younger, and Remain Socially and Professionally Engaged Should Address Hearing Loss, BHI Advises 3Men Who Want to Stay Active, Feel Younger, and Remain Socially and Professionally Engaged Should Address Hearing Loss, BHI Advises 4
    ... , ST. LOUIS, Jan. 7 KV ... the inspector of elections retained by the Company, has certified ... received by the Company on December 22, 2009 (the "Written ... stockholders (the "Director Changes") are sufficient to approve the matters ...
    ... , TUCSON, Ariz., Jan. 7 The Providence Service ... and Chief Executive Officer, is scheduled to present an overview of ... Cap Conference on Monday, January 11, 2010 at The Grand Hyatt ... 1:50 p.m. ET. , On Thursday, January 14, 2010, ...
    Cached Medicine Technology:KV Pharmaceutical Receives Report From Inspector of Elections Certifying Votes to Approve Appointment of Director 2KV Pharmaceutical Receives Report From Inspector of Elections Certifying Votes to Approve Appointment of Director 3KV Pharmaceutical Receives Report From Inspector of Elections Certifying Votes to Approve Appointment of Director 4KV Pharmaceutical Receives Report From Inspector of Elections Certifying Votes to Approve Appointment of Director 5KV Pharmaceutical Receives Report From Inspector of Elections Certifying Votes to Approve Appointment of Director 6KV Pharmaceutical Receives Report From Inspector of Elections Certifying Votes to Approve Appointment of Director 7Providence Service Corporation to Present at the Sidoti & Company, LLC Micro Cap Conference on Monday, January 11th and at the CJS Securities 'New Ideas for the New Year' Conference on Thursday, January 14th 2
    (Date:5/25/2013)... Forney, United States (PRWEB) May 25, 2013 ... oldest and largest underground shelter company in the ... and composite underground structures for over 35 years. ... of PROTECTION, U.S. Handbook of NBC Weapon Fundamentals ... is the United States’ bible on shelter engineering. ...
    (Date:5/25/2013)... (PRWEB) May 25, 2013 Absolute Surgical Specialists, ... many of the NALA’s businesses throughout the country participating in ... to participate in the nationwide event as he understands what ... Colonel in the Army. He said, “I wanted to give ... I serve, but I live here too.” , Shop Local ...
    (Date:5/25/2013)... 25, 2013 The latest report ... irritable bowel syndrome (IBS) to bloating, constipation, diarrhea ... most long-lasting, embarrassing, frustrating and difficult health issues ... digestive health have provided a cure for ... factors contributing to digestive health issues, a healthy ...
    (Date:5/25/2013)... 2013 According to a new ... 2013–2018", published by MarketsandMarkets is expected to reach ... 5.54% which analyzes and studies the major market ... Asia, and Rest of the World. , Browse:, ... , 87 Figures , ...
    (Date:5/25/2013)... Vancouver, BC (PRWEB) May 25, 2013 ... of the most beautiful and powerful women that ever ... was felt by some of the most powerful men ... used many beauty remedies to keep her skin glowing ... treatments made with bees- wax, maringa oil and cyprus ...
    Breaking Medicine News(10 mins):Health News:Radius Engineering International Inc. Offers Tools to Stay Safe and Recover From Any Disaster 2Health News:Radius Engineering International Inc. Offers Tools to Stay Safe and Recover From Any Disaster 3Health News:Dr. Craig Amshel of Absolute Surgical Specialists Offering Bowel Prep During the Shop Local for a Cause Event 2Health News:Natural Foods For Digestive Health Report and Video Published by BetterDigestion.org 2Health News:Homeland Security Market to Reach $544.02 Billion by 2018 at a CARC of 5.54% - New Report by MarketsandMarkets 2Health News:Homeland Security Market to Reach $544.02 Billion by 2018 at a CARC of 5.54% - New Report by MarketsandMarkets 3Health News:Homeland Security Market to Reach $544.02 Billion by 2018 at a CARC of 5.54% - New Report by MarketsandMarkets 4Health News:The Cleopatra Lift - A New Non Surgical Option to Aging Offered by Vancouver Physician 2Health News:The Cleopatra Lift - A New Non Surgical Option to Aging Offered by Vancouver Physician 3
    ... Profitability, CARLSBAD, Calif., Feb. 12 Genoptix, Inc.,(Nasdaq: ... reported,revenues of $18.6 million for the fourth quarter ended ... $7.8 million for the comparable period,in 2006. For the ... of $59.3 million, an increase of 147% over revenues ...
    ... Feb. 12 AtriCure, Inc.,(Nasdaq: ATRC ), a ... products, announced today that David J. Drachman, President and,Chief ... Capital,Partners 20th Annual OC Growth Stock Conference at the ... February 20th at 2:00 p.m.,PT., A live web ...
    ... of anxiety may cause women with ductal carcinoma in ... cancer, to overestimate their risk of recurrence or dying ... at Dana-Farber Cancer Institute in Boston. , "Although DCIS ... DCIS develop inaccurate risk perceptions," said Ann Partridge, MD, ...
    ... answers the research offers , , TUESDAY, Feb. 12 ... one of the most pressing questions in critical care ... open the partially collapsed lungs of people being treated ... , Unfortunately, that question has not been definitively answered. ...
    ... cancer specialists at Jeffersons Kimmel Cancer Center in Philadelphia ... for liver cancer. The therapy entails injecting tiny beads ... main artery while also blocking the blood supply feeding ... been approved by the federal Food and Drug Administration ...
    ... 50, 75 and 100 mcg/hr) Not Affected, ... Pharmaceuticals, Inc. said today that all lots of ... by PriCara in the United States and all ... the United States are being voluntarily,recalled as a ...
    Cached Medicine News:Health News:Genoptix Reports Strong Financial Results for the Fourth Quarter and Full Year 2007 2Health News:Genoptix Reports Strong Financial Results for the Fourth Quarter and Full Year 2007 3Health News:Genoptix Reports Strong Financial Results for the Fourth Quarter and Full Year 2007 4Health News:Genoptix Reports Strong Financial Results for the Fourth Quarter and Full Year 2007 5Health News:Genoptix Reports Strong Financial Results for the Fourth Quarter and Full Year 2007 6Health News:Genoptix Reports Strong Financial Results for the Fourth Quarter and Full Year 2007 7Health News:Genoptix Reports Strong Financial Results for the Fourth Quarter and Full Year 2007 8Health News:AtriCure to Present at Roth Capital Partners 20th Annual OC Conference 2Health News:Anxiety linked to newly diagnosed DCIS patients' overestimation of breast cancer risks 2Health News: Respiratory Distress Treatment Studies Conflict 2Health News: Respiratory Distress Treatment Studies Conflict 3Health News:New Jefferson trial to test radiation-emitting beads against advanced liver cancer 2Health News:PriCara(TM) Recalls 25 mcg/hr DURAGESIC(R) (fentanyl transdermal system) CII Pain Patches 2
    ... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
    ... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
    ... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
    ... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
    Medicine Products: