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Lexicon Announces Proposed $95 Million Common Stock Offering
Date:3/8/2010

160;Words such as "will," "intends" and similar expressions are intended to identify these forward-looking statements.  There are a number of important factors that could cause Lexicon's results to differ materially from those indicated by these forward-looking statements, including risks and uncertainties related to market conditions and the satisfaction of customary closing conditions related to the proposed public offering.  There can be no assurance that Lexicon will be able to complete the proposed public offering on the anticipated terms, or at all.  Additional risks and uncertainties relating to the proposed public offering, Lexicon and its business can be found under the headings "Factors Affecting Forward-Looking Statements" and "Risk Factors" in Lexicon's annual report on Form 10-K for the year ended December 31, 2009, as filed with the Securities and Exchange Commission, and under the heading "Risk Factors" in the preliminary prospectus supplement related to the proposed public offering to be filed with the Securities and Exchange Commission on March 8, 2010. Unless required by applicable law, Lexicon undertakes no obligation to update or revise any such forward-looking statements, whether as a result of new information, future events or otherwise.

SOURCE Lexicon Pharmaceuticals, Inc.

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