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Leonhardt Ventures to Present Technology Showcase @ Heart Rhythm 2013
Date:5/1/2013

of inventing, developing, backing and bringing to market leadership products for treating heart and cardiovascular disease. Over 200,000 patients have been treated to date with Leonhardt inventions.  In the 1980's the group developed market leadership in patented polyurethane balloon catheters including drug, stem cell and radiation delivery systems.  In the 1990s they developed over 20 additional devices including the first commercially successful stent graft for aortic aneurysm repair (TALENT – Taheri-Leonhardt Stent Graft).  The team completed the first ever truly percutaneous repair of an aortic aneurysm without surgery in Melbourne, Australia in 1995.  Published the first thoracic aortic dissection repair with stent grafts paper in The New England Journal of Medicine in 1999.  The first conformance sealing stent graft.  The first above renal fixation stent graft.  The first customized to fit individual patient stent grafts.  The first multi-stage low profile stent graft.  The first removable stent graft.  The first foam and bioglue sealing cuff for stent grafts.  The first use of muscle stem cells to reinforce aortic wall necks after stent graft placement.   The team developed and patented the first percutaneous heart valve, intravascular lung catheter, the Pro-Cell intracavity stem cell delivery system and the MyoCath line of stem cell delivery catheters.  Leonhardt patented inventions include the first heart pacemaker able to recruit reparative stem cells to damaged heart tissue (MyoStim Pacers).  In 2001 the team led the first in the world non-surgical case of stem cell repair of damaged heart muscle in a human patient with Bioheart MyoCell.  That led to the first Phase III double blinded, randomized, placebo controlled trial for stem cells growing new contractile muscle in post heart attack tissue in advanced heart failure patients – results published in t
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