Navigation Links
Leading Researchers Outline Principles for Conduct of Comparative Effectiveness Research
Date:9/11/2012

WASHINGTON, Sept. 11, 2012 /PRNewswire-USNewswire/ -- A new set of principles developed by a group of leading researchers could help to ensure more consistency in how comparative effectiveness research (CER) is planned and conducted. These guiding principles were published today in the September issue of The Journal of Comparative Effectiveness Research.

The principles and paper were developed by Bryan R. Luce, Ph.D., MBA, United BioSource Corporation and the University of Washington; Michael F. Drummond, Ph.D., University of York; Robert W. Dubois, MD, Ph.D., National Pharmaceutical Council; Peter J. Neumann, ScD, Tufts Medical Center and Tufts University School of Medicine; Bengt Jonsson, Ph.D., Stockholm School of Economics (Sweden); Uwe Siebert, MD, MPH, MSc, ScD, University of Health Sciences, Medical Informatics and Technology (Austria) and Harvard School of Public Health; and J. Sanford Schwartz, MD, Wharton School of Business and Perelman School of Medicine, University of Pennsylvania.

"These are voluntary principles that can help to improve the quality of CER, which in turn can help patients and providers make better treatment decisions," said Dr. Luce. "For CER to succeed in guiding health decisions, it should be planned and conducted with rigor and transparency."

To arrive at these best research practice principles, the researchers examined existing health technology assessment principles and engaged multiple CER experts and stakeholders for feedback.

The resulting 13 principles include ensuring that the research objectives are clear, being transparent in how the research is conducted, involving stakeholders, including especially relevant decision makers, in a meaningful way throughout the research process, considering perspectives and interests from a wide range of stakeholders, using relevant comparators, and evaluating relevant outcomes and the impact of individual treatment effects on patients. The researchers acknowledge that "no one study will necessarily be able to fully meet every principle to the letter," but that CER should always endeavor to fulfill, and never ignore, their intent.

"Going forward, it will be important to evaluate how well CER studies adhere to these principles. We can then determine whether CER studies that use those principles are having an impact on patient care or are being appropriately adopted into guidelines and clinical practice," said Dr. Dubois.

About the National Pharmaceutical Council
The National Pharmaceutical Council is a health policy research organization dedicated to the advancement of good evidence and science, and to fostering an environment in the United States that supports medical innovation. Founded in 1953 and supported by the nation's major research-based pharmaceutical companies, NPC focuses on research development, information dissemination, and education on the critical issues of evidence, innovation and the value of medicines for patients. For more information, visit www.npcnow.org and follow NPC on Twitter @npcnow.

About the Journal of Comparative Effectiveness Research
The editorial direction of Journal of Comparative Effectiveness Research (www.futuremedicine.com/loi/cer) is the responsibility of Senior Editors, Prof. Sheldon Greenfield (University of California, Irvine) and Dr. Eugene Rich (Mathematica Policy Research, Washington, DC). The Senior Editors are supported by a team of six Associate Editors, together with an Advisory Panel of 40 international experts. London-based publishers Future Medicine are part of the Future Science group and are specialists in providing healthcare practitioners and research professionals with high-quality evaluated information. For more details, including free trials to the journal, or to contribute, please contact the Launch Editor Laura Dormer (L.Dormer@futuremedicine.com).

 


'/>"/>
SOURCE National Pharmaceutical Council
Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. Pinnaclife Is Excited to Continue Its Partnership With Leading Dermatological Veterinarians
2. Leading Prostate Cancer Group Says New Drug Gives Hope To Men With Advanced Prostate Cancer
3. Mylan Selected as a Leading ARV Supplier to Indias National AIDS Control Organization
4. Mt. Airy Hospital Selects Sound Physicians - Leading Hospitalist Organization Focuses on Improving Quality and Reducing Cost of Inpatient Care
5. National Call-to-Action to Boost Meningitis Vaccination Rates Supported by Leading Health Organizations, Urges Minneapolis-St. Paul Parents to Vaccinate Preteens and Teens
6. National Call-to-Action to Boost Meningitis Vaccination Rates Supported by Leading Health Organizations, Urges Nashville Parents to Vaccinate Preteens and Teens
7. National Call-to-Action to Boost Meningitis Vaccination Rates Supported by Leading Health Organizations, Urges St. Louis Parents to Vaccinate Preteens and Teens
8. Leading Medical Technology Company Selects inContact to Transform Service Experience
9. Makers Of Over-the-Counter Inhaler Leading Fight To Have Product Back On Market After Removal Due To Environmental Treaty
10. Pulse Oximetry Screening Hailed as the New Milestone to Combat Critical Congenital Heart Disease - Signal Extraction Technology Leading the Way in Large, Independent Clinical Studies
11. AstraZeneca and Leading Academic Scientists to Collaborate on Alzheimers Disease Research
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/21/2017)... ARMO BioSciences, Inc., a late-stage immuno-oncology company, ... lead investigational immuno-oncology drug AM0010 (PEGylated Interleukin-10) at the ... of Clinical Oncology (ASCO), taking place January 19-21, 2017 ... "AM0010 induces the expansion of novel T ... in the blood and tumors of our patients," said ...
(Date:1/20/2017)... , Jan 20, 2017 Research ... Testing Market By Type ([CBC, HGB/HCT, BMP, BUN Creatinine, Electrolyte Testing, ... By End-use, And Segment Forecasts, 2013 - 2024" report to ... ... 198.5 billion by 2024 Introduction of innovative solutions on ...
(Date:1/20/2017)... DUBLIN , Jan 20, 2017 ... Pharmaceutical Stability Testing Market Trends, Opportunities, and Future" report to ... ... market sizing, emerging trends, and technologies, and provides a snapshot of ... year is 2015 and forecasts are provided from 2016 to 2020. ...
Breaking Medicine Technology:
(Date:1/20/2017)... ... 2017 , ... Source Vitál Apothecary, a skin and body care company dedicated ... company had a successful visit to the 2017 ECRM Diet, Vitamin & Sports Nutrition ... in the nutritional, sports and health industries a chance to meet in private sessions ...
(Date:1/20/2017)... ... January 20, 2017 , ... Lice Troopers, the lice removal company ... with school-aged children since the holiday season. , “It happens every year around ... sharing hugs and taking photos, which is the head-to-head gateway that lice need to ...
(Date:1/20/2017)... ... 2017 , ... Michael and Betsy Brauser celebrated 5 years of Betsy’s participation ... trial has been life-saving as she has been on the trial for more ... diagnosed with ovarian cancer in 2009. She underwent standard chemotherapy but a year later ...
(Date:1/20/2017)... ... ... Magdalene: Grace is Greater than Sin”: a unique and memorable piece of literature ... Grace is Greater than Sin” is the creation of published author, Brenda Roberts, a ... had little knowledge of the female characters portrayed in the Holy Bible. , ...
(Date:1/20/2017)... ... ... examination of how God handles sin, including how to let go of lingering guilt and ... ten long years has been waiting to release this powerful insight about forgiveness that the ... the Lord for over twenty years, and he has been preaching and teaching the Word ...
Breaking Medicine News(10 mins):