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Leading Physicians Present Interim Results from Multi-Center Studies of VNUS ClosureFAST Catheter at VEITHsymposium
Date:11/14/2007

SAN JOSE, Calif., Nov. 14 /PRNewswire-FirstCall/ -- VNUS(R) Medical Technologies, Inc. (Nasdaq: VNUS), a worldwide leader in medical devices for the minimally invasive treatment of venous reflux disease, announced that interim results from two multi-center studies using the VNUS ClosureFAST catheter were presented today at the 34th Annual VEITH Symposium in New York. The VNUS ClosureFAST(TM) catheter is an endovenous radiofrequency (RF) ablation catheter designed to heat and close diseased saphenous veins - the underlying cause of varicose veins.

In a presentation titled "ClosureFAST Is Better Than First Generation Radiofrequency Ablation: A Quantum Leap Forward", Alan Dietzek, MD., Chief of Vascular Surgery and Linda and Stephen R Cohen Chair in Vascular Surgery at Danbury Hospital in Danbury, Connecticut, presented one-year follow-up results of ClosureFAST patients from a multi-center prospective study including 13 centers in the US and Europe. Among 324 patients (395 limbs) in the study, 142 limbs had one-year followup data, with a vein occlusion rate of 96.2% at one year using Kaplan-Meier analysis.

"VNUS ClosureFAST is a major step forward in the management of venous disease," said Dr. Dietzek. "Results so far have exceeded expectations, especially the excellent treatment efficacy combined with very mild postoperative patient recovery. Furthermore, with ClosureFAST it is now possible to perform endovenous ablation of the saphenous vein as fast or faster than with any other device or mode of treatment available."

Jose I. Almeida, MD., FACS, founder of the Miami Vein Center in Miami, Florida and a recognized expert in varicose vein treatment, presented the interim results of the Recovery trial, a multi-center randomized trial comparing the ClosureFAST treatment to endovenous laser. Patients undergoing laser treatment were 33% more likely to experience pain and 50% more likely to require postoperative pain medication than patients who received the ClosureFast treatment.

"The ClosureFAST device is clearly emerging as the preferred treatment for venous reflux, in part because of reduced patient discomfort after treatment," said Dr. Almeida. "While procedure time and short-term efficacy are comparable between ClosureFAST and laser, we're definitely seeing a superior patient recovery profile with ClosureFAST."

"We are pleased to see the positive interim study results on our ClosureFAST catheter, especially the favorable patient recovery profile compared to laser treatment and the better-than-anticipated one-year efficacy rate," said Brian E. Farley, President and CEO of VNUS. "We believe the final results will support our belief that ClosureFAST is the best choice for the treatment of venous reflux disease for the millions of varicose vein sufferers around the world."

ABOUT VEITH SYMPOSIUM

Now in its fourth decade, VEITHsymposium provides vascular surgeons, interventional radiologists, interventional cardiologists and other vascular specialists with a unique and exciting format to learn the most current information about what is new and important in the treatment of vascular disease. The five-day event features rapid-fire presentations from world renowned vascular specialists with emphasis on the latest advances, changing concepts in diagnosis and management, pressing controversies and new techniques. VEITHsymposium is sponsored by The Cleveland Clinic, Cleveland, OH.

ABOUT VNUS MEDICAL TECHNOLOGIES, INC.

Founded in 1995 and headquartered in San Jose, California, VNUS Medical Technologies (Nasdaq: VNUS) is a worldwide leader in medical devices for the minimally invasive treatment of venous reflux disease, a progressive condition that causes the varicose veins afflicting 25 million Americans. The pioneering company in the field, VNUS now offers the ClosureFAST system, which consists of a proprietary radiofrequency (RF) generator and proprietary disposable endovenous catheters and devices to close diseased veins through the application of temperature-controlled RF energy. VNUS devices have been used in more than 250,000 procedures worldwide. For more information, please visit http://www.vnus.com.


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SOURCE VNUS Medical Technologies, Inc.
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