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Leading Experts Endorse Bioheart's Muscle Stem Cell MyoCell Therapy
Date:7/7/2009

. "I'll never forget the home run. We were able to show that we could grow new muscle in the center of ischemic myocardium and improve functional outcome." Dr. Nabil Dib, Director, Cardiovascular Research, Mercy Gilbert & Chandler Medical Centers, added that "Myoblast transplantation to patients with congestive heart failure and specifically to scar tissue (not living tissue) has shown that the cells survive, engraft and form new muscle and they do excrete fatigue resistant proteins similar to the heart muscle protein." Dr. HJ Duckers, Interventional Cardiologist, Thoraxcenter, Rotterdam discussed the history of the Bioheart trials in Europe to date and added that "the myoblast therapy is at this time point the only stem cell therapy that is making the claim to actually induce neomyogenesis and that is why it deserves our attention."

Dr. Warren Sherman, Director, Stem Cell Research and Regenerative Medicine, Columbia University Medical Center, discussed the anticipated MARVEL study, "this study, once completed, will be the bench mark and we are all very optimistic. Thomas Povsic, Assistant Professor of Medicine, Duke University Medical Center worked directly with the investigational sites on the MARVEL study and commented on "the enthusiasm by the investigators that were involved in the study to get patients in and the enthusiasm that the patients have to get into this study."

Bioheart's latest Phase II/III MARVEL study has undergone interim analysis and although data are not disclosed due to pending publication confidentiality, the panel of experts has reviewed these data and has unanimously and enthusiastically endorsed moving forward to finish the pivotal studies to bring this product to FDA approval based on their review.

Research by these experts and others has shown that myoblasts may have an advantage over other cell types in treating heart failure as they can survive in low oxy
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SOURCE Bioheart, Inc.
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