Navigation Links
Launch of Nuromol a New Painkiller Combination
Date:6/28/2011

LONDON, June 28, 2011 /PRNewswire/ --


 

Stronger and Effective for Longer Versus Standard Paracetamol
Tablets
, as Shown in a Dental Pain Study[1]

A new non-prescription painkiller is now available in pharmacies across the UK, heralding the first UK painkiller combination of ibuprofen and paracetamol in 'over-the-counter' pain relief. NUROMOL is the UK's first clinically-proven painkiller to combine the power of ibuprofen and paracetamol in one tablet. In a dental pain study, one tablet of Nuromol was shown to provide pain relief that is significantly stronger than a 1000mg paracetamol and 30mg codeine combination[2*].  

*The maximum OTC dose in the UK is 1000mg paracetamol and 25.6mg codeine.  This comparison relates to cumulative pain relief over 12 hours following a single dose.

'NUROMOL is a new painkiller, which we hope will help more people obtain stronger pain relief than you can get from ibuprofen or paracetamol alone,' says Trevor Gore, Training Manager, Healthcare,  'and NUROMOL is available without a prescription in pharmacies across the country.'

 'Paracetamol and ibuprofen work in different ways to relieve pain,' says Dr Hicks.   'It makes absolute sense to combine these two painkillers in one tablet, making it ideal for people with dental pain, migraine, and period pains, which may require stronger and longer-lasting pain relief than can be delivered by either ibuprofen or paracetamol on their own.'

Why is a new painkiller needed?  

Pharmacies already sell a baffling range of different painkillers - many of them containing combinations of different products. A closer look at the labels, however, reveals that the vast majority contain either ibuprofen or paracetamol, sometimes in combination with caffeine or a mild opioid such as codeine.[3] All these painkillers work in different ways; some (e.g. paracetamol) work in the brain to block pain signals, while others (e.g. ibuprofen) also work at the site of pain.

Ibuprofen and paracetamol have a well established safety profile and are recommended and used by GPs and pain specialists around the world.[3] Codeine-containing painkillers can potentially lead to dependency and addiction after prolonged use,[3] which has recently prompted the UK health authorities to restrict their use, limit pack sizes, and add prominent warnings to labels and advertising.[4]

Although currently-available, non-prescription painkillers are effective for most people but a recent Opinion Health survey[5] found that over 80% of respondents had taken a painkiller that had not offered sufficient pain relief or relieved their pain for long enough. Dental pain appears to be particularly difficult to treat, with over half (58%)[5] of survey respondents reporting they had suffered from dental pain that was not relieved through taking painkillers.

NUROMOL has been extensively studied in people with severe dental pain after tooth extraction. The recommended dose provides up to eight hours of pain relief.[6]

'If people are not happy with the level of pain relief they get from their usual over-the-counter pain medications, they should talk to their pharmacist about suitable alternatives,' concluded Dr Hicks.

Notes to Editors

  • http://www.nuromol.co.uk is now live
  • NUROMOL is available from pharmacies across the UK
  • NUROMOL is an oval shaped film-coated tablet combining ibuprofen 200mg and paracetamol 500mg.

 In a dental pain study, one tablet of Nuromol was shown to provide pain relief that is significantly stronger than a 1000mg paracetamol and 30mg codeine combination.[2*]

*The maximum OTC dose in the UK is 1000mg paracetamol and 25.6mg codeine.  This comparison relates to cumulative pain relief over 12 hours following a single dose.

  • If one tablet is not sufficient to relieve symptoms then the dosage maybe increased to two tablets still leaving 6 hours between doses.  Nuromol should be taken with water and food for the shortest duration of time necessary to relieve symptoms and for no more than 3 days.
  • Two tablets were shown to offer stronger pain relief which lasted for longer than 400mg ibuprofen and 25.6mg codeine combination.[2]
  • For adults over 18 years, one tablet (or two tablets if one tablet does not control symptoms) of NUROMOL can be taken up to three times per day with water and food. At least 6 hours should be left between doses.  No more than six tablets should be taken in any 24-hour period.
  • People should use the lowest effective dose for the shortest time necessary to relieve their symptoms.
  • NUROMOL comes in tablet form and is available from pharmacies. The product will be available in a range of pack sizes, and has a RRP of £2.49 for six tablets.

Nuromol is the first combination of paracetamol (500mg) and ibuprofen (200mg) available over-the-counter in the UK.  Always read the leaflet. Nuromol is a registered trade mark of Reckitt Benckiser.

References

  1. Mehlisch DR, Aspley S, Daniels SE, Southerden KA, Christensen KS. A single-tablet fixed-dose combination of racemic ibuprofen/paracetamol in the management of moderate to severe postoperative dental pain in adult and adolescent patients: a multicenter, two-stage, randomized, double-blind, parallel-group, placebo-controlled, factorial study. Clin. Ther. 2010;32:1033-1049
  2. RB Data on File: Study No.NL0811.2010
  3. The British Pain Society. Managing your pain effectively using "Over the Counter" (OTC)
  4. MHRA Public Assessment Report.  Codeine and dihydrocodeine containing medicines: minimising the risk of addiction.  September 2009.
  5. Opinion Health analgesic consumer survey involving 1800 members of the general public. December 2010.
  6. Nuromol SmPC MA Number: PL00063/0579

 



'/>"/>

SOURCE Reckitt Benckiser
Copyright©2010 PR Newswire.
All rights reserved

Related medicine technology :

1. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
2. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
3. Iomai Launches Phase 1/2 Safety Study of Dose-Sparing Patch for Use With Pandemic Influenza Vaccine
4. Keeping the Data Center Clean: ATEN Launches Industry-First KVM Switches with Antimicrobial Nanocoating to Protect Products from Bacteria Surviving on Surfaces
5. Cell Therapeutics, Inc. (CTI) Launches Phase III Study for Pixantrone in Relapsed Indolent Non-Hodgkins Lymphoma (NHL)
6. Tengion Launches Second Phase 2 Clinical Trial of Regenerated Human Organ
7. Strategic Diagnostics Launches Initial Oncology-Targeted Antibody Reagent Catalog
8. deCODE Launches Phase II Clinical Testing of DG051 for the Prevention of Heart Attack
9. Premier Micronutrient Launches Supplement for Hearing Health
10. deCODE Launches deCODE MI(TM) -- A Test for a Major Genetic Risk Factor for Early-onset Heart Attack
11. Actress and New Mom Keri Russell Joins PKIDs to launch Silence the Sounds of Pertussis Campaign
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:5/30/2017)... Israel , May 30, 2017 DarioHealth Corp. (NASDAQ: ... big data solutions, today announced that it will be presenting at ... at 8:00 AM PT. Erez Raphael , CEO, of DarioHealth ... The conference will be held on June 6th & 7th, 2017 ... companies in the small / micro-cap space. ...
(Date:5/29/2017)... May 29, 2017  Cellect Biotechnology Ltd. (NASDAQ: ... which enables the functional selection of stem cells, today ... the first quarter ended March 31 st , 2017. ... accomplishments in the first quarter of 2017," said Dr. ... we announced the treatment of the first blood cancer ...
(Date:5/24/2017)... 2017  ivWatch LLC today announced the launch ... to enable seamless integration of ivWatch,s groundbreaking IV ... pumps and other devices. By integrating ivWatch technology ... help health care customers deliver a higher level ... IV therapy. "The ivWatch OEM Board ...
Breaking Medicine Technology:
(Date:6/24/2017)... ... June 24, 2017 , ... The Pennsylvania ... Sheraton Erie Bayfront and Erie Convention Center on June 8-10. The weekend ... student quiz bowl, award and scholarship presentations, and professional networking. , On ...
(Date:6/24/2017)... ... June 24, 2017 , ... Doorknobs are for convenience, deadbolts ... as getting a guard dog or having an alarm system installed. But unless there ... forced entry. Yair Frenkel, owner of TX Premier Locksmith in Killeen, TX says: “In ...
(Date:6/23/2017)... CA (PRWEB) , ... June 23, 2017 , ... By ... earned its ninth consecutive four-star rating from premier online charity evaluator, Charity Navigator, validating ... the top 1% of all charities reviewed by Charity Navigator and earns ANRF a ...
(Date:6/23/2017)... , ... June 23, 2017 , ... The Military Officers ... nominee for deputy secretary of Veterans Affairs, retired Marine Col. Thomas G. Bowman. , ... , Bowman brings an intimacy with the issues and challenges veterans face ...
(Date:6/23/2017)... ... , ... Everybody has their own personal preference when it comes to pornography. ... people don't like it at all. FindaTopDoc took a look at what makes people ... give readers a taste of their deepest, darkest fantasies and has the ability to ...
Breaking Medicine News(10 mins):