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Launch Of Premium-priced, Novel Targeted Therapies Will Drive Growth In The Acute Leukemia Markets Beginning In 2015
Date:1/30/2013

BURLINGTON, Mass., Jan. 30, 2013 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms focusing on pharmaceutical and healthcare issues, forecasts the launch of new agents positioned for the treatment of both acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML) through 2018. According to two Niche Markets and Rare Diseases reports, Acute Lymphoblastic Leukemia and Acute Myeloid Leukemia, novel targeted therapies hold the most promise for improving outcomes for patients with acute leukemia. Interviewed experts are enthusiastic about the potential of Amgen/MicroMet's blinatumomab–a first-in-class bispecific T-cell engager–for the treatment of ALL. Experts also highlight the potential of Ambit Biosciences/Astellas Pharma's quizartinib in AML: quizartinib will be the first agent that will be targeted to a specific AML sub-population, those patients with mutations in FLT3. However, clinical benefit in relapsed/refractory patients that do not harbor mutations in FLT3 suggests that uptake of the drug in a wider population is anticipated.

"The late-stage acute leukemia pipeline has shown a lot of promise lately, and experts are excited at the prospect of having more targeted therapies available to add to traditional chemotherapy options," said Decision Resources Therapy Leader Joanne Graham , Ph.D. "New formulations of existing chemotherapies will also play a role in the late-stage pipeline. Despite the promise of novel targeted drugs, there is no doubt that the future treatment of acute leukemia will continue to rely heavily on chemotherapies."These reports also find that, despite the launch of several new agents throughout the forecast period, there are still high levels of unmet need in the acute leukemia space, especially for treatments that provide improved efficacy outcomes for, and are less to
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SOURCE Decision Resources
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