Navigation Links
Late-Breaking ASCO Data Demonstrate Circulating Tumor Cells as Potential Biomarker for Metastatic Prostate Cancer Clinical Trials
Date:6/4/2011

gating the potential predictive benefit of CTCs in metastatic prostate cancer clinical trials as there are limited ways of assessing therapeutic benefit in this disease, especially when it has metastasized to the bone."

Additional studies are underway to further validate CTCs as a surrogate endpoint in metastatic prostate cancer studies.

Study Design

The CTC analysis was conducted to determine if CTCs could be used as a surrogate for overall survival.  It was performed in 900 of the 1195 enrolled study patients with metastatic castration-resistant prostate cancer post-docetaxel being treated with either abiraterone acetate plus prednisone or placebo plus prednisone.  CTCs were counted (cells/7.5 mL) along with other biomarkers including PSA, LDH, hemoglobin, alkaline phosphatase at screening and baseline and post-baseline at four, eight and 12 weeks. Analyses were conducted for these biomarkers individually and collectively.

Veridex provided product support for the study. 

Dr. Howard Scher has provided consulting services to the company. 

Additional Data Presented at ASCO Substantiates In Vitro Diagnostic Use of CELLSEARCH® CTC Test

An independent study investigating the in vitro diagnostic use of CTC testing found that the number of CTCs in the blood may help physicians more reliably assess treatment benefit for patients with metastatic breast cancer.  The study, a large-scale retrospective analysis using blinded data to create a pooled dataset of 841 patients from cancer centers around the world, found that CTC count at or above the threshold of five was reliably associated with disease progression.  Further, the predictive value of CTCs was not affected by treatment type (chemotherapy, endocrine therapy, biologic therapy), tumor type (hormone receptor positive/negative, HER2 positive/negative),
'/>"/>

SOURCE Veridex, LLC
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4

Related medicine technology :

1. Pervasis Therapeutics Announces Late-Breaking Oral Presentation at American Association for Cancer Research Annual Meeting
2. American Stroke Association Late-Breaking Science Report: New Drug as Effective as Warfarin in Preventing Strokes in Atrial Fibrillation Patients With Prior Stroke or TIA
3. American Stroke Association Late-Breaking Science Report: Antiplatelet Drug May Be Better Than Aspirin in Preventing Recurrent Strokes
4. American Heart Association Late-Breaking Clinical Trial Report: New Reversible Oral Drug Reduces Cardiac Events in Primary PCI Patients
5. American Heart Association Late-Breaking Clinical Trial Report: New Blood Thinner for Angioplasty Patients Not Superior for Primary Endpoint, but Did Reduce Death and Stent Thrombosis
6. MultiVu Video Feed: POSITIVE PHASE 3 TRIAL DATA FOR INVESTIGATIONAL NEW MIGRAINE TREATMENT PRESENTED IN LATE-BREAKING SESSION AT 14th ANNUAL INTERNATIONAL HEADACHE SOCIETY CONGRESS
7. MAP Pharmaceuticals Analysis of Positive Phase 3 LEVADEX(TM) Data To Be Presented in Late-Breaking Session at 14th Congress of the International Headache Society
8. Impulse Dynamics Announces Pivotal Results at the American College of Cardiology Annual Meeting Late-Breaking Session
9. Results From Efficacy and Safety Study of Cortheras Relaxin in Acute Heart Failure to be Presented at Late-Breaking Clinical Trials Session at ACC 58th Annual Scientific Session
10. Atritech to Participate in Late-Breaking Clinical Trial Presentation at American College of Cardiology Meeting
11. Late-Breaking Data Highlighting Research Advances in Several Blood Disorders to Be Presented At the American Society of Hematology Annual Meeting
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:3/31/2015)... March 31, 2015 Point-of-Care Partners, a ... consulting firm, has launched the ePA State Navigator ... IT vendors, payers and pharmacies to quickly assess ... authorization (ePA) of prescription medications. Today, ... are completed through time-consuming, manual processes amongst prescribers, ...
(Date:3/31/2015)... ROCHELLE, N.Y. , March 31, 2015 /PRNewswire-USNewswire/ ... it will be featured in the American Medical ... by ITN Productions. AMGA,s "High Performing ... on the challenges facing the nation,s healthcare system ... Medical Letter is profiled along with other leading ...
(Date:3/31/2015)... March 31, 2015 RnRMarketResearch.com ... market research report of 68 pages with latest ... intelligence library. The report "Pemphigus - Pipeline Review, ... therapeutic development for Pemphigus , complete with ... drug target, mechanism of action (MoA), route of ...
Breaking Medicine Technology:Point-of-Care Partners Launches the ePA State Navigator 2AMGA's High Performing Health News Program Features The Medical Letter 2Pemphigus Therapeutic Development and Pipeline Review H1 2015 2Pemphigus Therapeutic Development and Pipeline Review H1 2015 3Pemphigus Therapeutic Development and Pipeline Review H1 2015 4
... , , ... Inc.,("Chindex") (Nasdaq: CHDX ), a leading independent American provider of ... that the Company will attend the 21st Annual Piper Jaffray,"Unplugged" Health ... the,New York Palace Hotel. , Management is ...
... SAN DIEGO, Nov. 24 Anadys Pharmaceuticals, Inc. (Nasdaq: ... 21st Annual Piper Jaffray Healthcare Conference on Tuesday, December 1, ... conference is being held at The New York Palace Hotel. ... Anadys, will provide an overview of Anadys and its clinical ...
Cached Medicine Technology:Chindex International to Present at Piper Jaffray Health Care Conference 2Anadys Pharmaceuticals to Present at the Piper Jaffray Healthcare Conference 2
(Date:4/1/2015)... 01, 2015 Decora Preset 30 Minute Countdown ... on ‘The Hardware City.’ The product helps in automatically switching ... time and the related electronic device is automatically turned off ... the company said, “We are glad that this amazing product ... buy Countdown Timer Switch in just a few clicks. The ...
(Date:4/1/2015)... Results are in for the fifth annual ... new homes from across the state exemplifying high-efficiency design. ... building techniques and new technology intended to lower energy ... (SWA) provided sustainability consulting services for 4 of the ... first- and third-place winners. , The Benker Residence, a ...
(Date:3/31/2015)... Due to its rapid expansion, ... caregivers, staffing personnel, and marketing managers, franchise sales ... the Greater Los Angeles area. In line with ... University has firmed up its training program and ... quality in-home care through a client-centered and service-oriented ...
(Date:3/31/2015)... 31, 2015 Over the last several ... technique have yielded better results and more efficient ... and perfected by a good hair transplant surgeon, has ... techniques of hair restoration have improved the efficiency of ... used to add precision and flexibility to the field ...
(Date:3/31/2015)... (PRWEB) March 31, 2015 In ... (ADS) is offering advice for buying from a ... Dealers Association (NMEDA) is a nonprofit organization that ... in the manufacturing and installation of mobility equipment. ... in the industry that consistently adhere to the ...
Breaking Medicine News(10 mins):Health News:Leviton Decora Preset 30 Minute Countdown Timer Available On TheHardwareCity.com 2Health News:Steven Winter Associates’ Projects Receive Top Honors in CT Zero Energy Challenge 2Health News:Steven Winter Associates’ Projects Receive Top Honors in CT Zero Energy Challenge 3Health News:Steven Winter Associates’ Projects Receive Top Honors in CT Zero Energy Challenge 4Health News:1Heart Ends 1st Quarter of the Year With 1Heart Caregiver University Training of New Staff and Commits To Provide More Jobs For Year 2015 2Health News:1Heart Ends 1st Quarter of the Year With 1Heart Caregiver University Training of New Staff and Commits To Provide More Jobs For Year 2015 3Health News:Beverly Hills Hair Transplant Surgeon Now Combines Advanced Robotic Hair Transplantation and Manual Techniques for Greatest Results 2Health News:Advanced Driving Systems Celebrates National Disability Month 2
... , SAN FRANCISCO, CA February 2, 2010 -- ... coronary heart disease worldwide, only some obese individuals go ... relatively protected. Defining these protective factors could help scientists ... this end, a research team at the Gladstone Institute ...
... , , KNOXVILLE, Tenn. , ... TMH ), one of the largest suppliers of outsourced healthcare ... in the United States , today announced that the Company ... the market closes on Tuesday, February 9, 2010 , to ...
... , SAN DIEGO , Feb. 3 For ... the top 100 integrated health care networks in the nation in an ... was ranked No. 6 in the nation and No. 1 in ... Modern Healthcare , is regarded as the nation,s premier rating system for ...
... , , TUCSON, Ariz. , ... ) today announced that Fletcher McCusker , Chairman and Chief Executive ... the UBS 20th Annual Global Healthcare Services Conference on Wednesday, February ... .   , Providence ,s presentation is scheduled for 10:00 ...
... , ... FDA is alerting the public about the following products: , ... Alli, 60 mg capsules (120-count refill kit) sold over the Internet ... Insulin Syringes may have needles that detach from the syringe and ...
... , MT. LAUREL, N.J. , Feb. ... transcription software and services, today announced that it has agreed ... provider of clinical documentation technology and services that recently filed ... place pursuant to Section 363 of the United States Bankruptcy ...
Cached Medicine News:Health News:Gladstone scientists identify target that may reduce complications of obesity 2Health News:TeamHealth Holdings, Inc. Announces Fourth Quarter and Full Fiscal 2009 Earnings Release Date and Conference Call 2Health News:TeamHealth Holdings, Inc. Announces Fourth Quarter and Full Fiscal 2009 Earnings Release Date and Conference Call 3Health News:Sharp HealthCare Rated Top Health Care Network in California and No. 6 in the Nation 2Health News:Providence Service Corporation to Present at the UBS Global Healthcare Services Conference on Wednesday, February 10th 2Health News:Providence Service Corporation to Present at the UBS Global Healthcare Services Conference on Wednesday, February 10th 3Health News:FDA Consumer Health Information - FDA's MedWatch Safety Alerts: January 2010 2Health News:MedQuist Agrees to Purchase Domestic Assets of Spheris 2Health News:MedQuist Agrees to Purchase Domestic Assets of Spheris 3
... latest 3-part differential analyzer based on the ... the CELL-DYN line. Offering 18 parameters and ... CELL-DYN 1800 meets the needs to today's ... than its predecessors and fits under standard ...
... produces high-quality blood films. Smearing parameters have ... time, eliminating the need to make adjustments ... hematocrit values. In the closed sampling mode, ... and aspirates only 200L. Only 30L of ...
... InstaCheck® Menopause Predictor Test is an in ... FSH in urine. Changes in FSH levels ... symptoms associated with stages of menopause. The ... obtain a visual, qualitative result and is ...
... diabetes continue to have a tremendous impact ... of patients, in addition to the significant ... be associated with elevated levels of blood ... haemoglobin A1c (HbA1c) in a diabetic patient's ...
Medicine Products: