Navigation Links
Laser Burn Injuries in One Eye Can Disrupt Protective Immune Privilege in Both Eyes, Study Finds
Date:2/26/2009

Findings have implications for treating returning vets and others exposed to laser burns

BOSTON, Feb. 26 /PRNewswire-USNewswire/ -- Scientists at Schepens Eye Research Institute have shown for the first time that a laser burn to one retina can cause both eyes to lose a special protective ability known as immune privilege. Immune privilege protects the eye without the inflammation of the body's normal immune response, which can further damage delicate eye tissue. This finding, published in the February 2009 American Journal of Pathology, has implications for treating patients with laser burns sustained on the battlefield and in other modern settings.

The discovery is also significant because it suggests a previously unknown communication between the two eyes. "This deepens our understanding of the way immune privilege works," says Dr. Joan Stein Streilein, principal investigator of the study and senior scientist at Schepens Eye Research Institute.

Immune privilege is a modification of the body's normal immune response. It protects the eye, the brain and the reproductive system without the full-blown immune response that uses inflammation to violently reject foreign tissue or invaders.

While inflammation in other parts of the body is a useful battle between immune and foreign cells, it is too aggressive for fragile eye, brain and reproductive tissues, and, in the case of the eye, can even lead to blindness. Immune privilege, which intervenes in the battle, is also what prevents the eye from rejecting corneal transplants, making them the most common and successful of transplanted tissues.

In her laboratory, Stein-Streilein and her team made tiny laser burns in one of the retinas of 15 mice. They then injected either the burned or the unburned eyes of each mouse with the antigen, Ovalbumin. Antigens are substances that the body perceives as foreign and against which it mounts a
'/>"/>

SOURCE Schepens Eye Research Institute
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Imaging Diagnostic Systems Updates PMA Filing Status for the New CT Laser Breast Imaging System
2. American Laser Center Offers VelaShape Body Shaping and Cellulite Reduction Treatment
3. UltraShape(R) Non-Invasive Fat Reduction and Body Contouring Clinical Study Results Featured at American Society for Laser Medicine and Surgery Meeting
4. Ekkyo Describes the First Benefits of Controlled Hyperthermia in Humans in "Lasers in Surgery and Medicine"
5. DOT Therapy: Newest Breakthrough Technology in Laser Skin Resurfacing
6. Blue Light Destroys Antibiotic-Resistant Staph Infection - Results Reported in Photomedicine and Laser Surgery Journal
7. Cytopia Concludes Phase I Oral Trial for Vascular-Disrupting Agent, CYT997
8. PharmAthenes Recombinant Butyrylcholinesterase (rBChE) May Play A Neuroprotective Role in Alzheimers Disease
9. Michael J. Fox Foundation Announces $5.6-Million Award for Phase 2 Clinical Trial Studying Neuroprotective Potential of Inosine
10. Preclinical Study Presented at AACR Annual Meeting Shows Peregrines Anti-PS Immunocytokines Can Generate Protective Immune Responses in a Highly Aggressive Breast Cancer Model
11. Anavex presents neuroprotective effects of Anavex 1-41 at the International Conference on Alzheimers Disease 2008
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)... July 11, 2014  Kindred Hospital Houston Northwest, ... the opening of its new outpatient wound healing ... to people with chronic, hard to heal wounds. ... lead to amputation, lower leg wounds related to ... closure, and traumatic injury wounds which are complex ...
(Date:7/11/2014)... On Thursday, July 10, ... Dow Jones Industrial Average finished the day 0.42% lower at ... The losses were broad based as eight out of ten ... Care Sector Index ended the day at 711.88, down 0.02%, ... month. Investor-Edge has initiated coverage on the following equities: Covidien ...
(Date:7/11/2014)... , July 11, 2014 Research ... addition of the "Immunoprotein Diagnostic Testing Market ... the highest CAGR of 6% and is expected ... report to their offering. ... immunoprotein diagnostic testing has been segmented according to ...
Breaking Medicine Technology:Kindred Hospital Houston Northwest, With Wound Care Specialists, Opens Outpatient Wound Healing And Hyperbaric Center 2Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 2Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 3Health Care Equipment Equities Movers and Shakers -- Research on Covidien, Baxter, DexCom, and Boston Scientific 4Immunoprotein Diagnostic Testing Market - Forecasts to 2019: Expected to grow at the highest CAGR of 6% and is expected to be valued at USD 4,943.0 million 2
... 2011 In conjunction with its first quarter 2011 earnings ... 4, 2011), Covance Inc. (NYSE: CVD ) is ... conference call that will be broadcast live over the Internet ... Covance First Quarter 2011 Earnings Webcast and Slide PresentationWhen: , ...
... Aribex®, Inc., the worldwide leader in handheld x-ray technologies, has ... premier Practice Management System for dental clinics, to contribute up ... the earthquake and tsunami in Japan. The first two kits ... of the most damaged areas. Each kit will ...
Cached Medicine Technology:Aribex and IDENS Donate 15 Victim I.D. Kits for Japan 2
(Date:7/13/2014)... identifies a novel genetic and molecular pathway ... opening up potential new therapeutic strategies for an ... is a chronic inflammatory disorder of the esophagus. ... certain foods and an over-accumulation in the esophagus ... the body,s immune system). EoE can cause a ...
(Date:7/13/2014)... North American water storage systems market is estimated to grow ... at a CAGR of 21.0%, from 2013 to 2018. The ... in North America. The U.S. is experiencing high growth on ... and collection, and the increased spending on modernization and upgradation ... rate in Canada, and is rising at a rapid pace ...
(Date:7/13/2014)... 2014 According to a new ... Market by Component (processor, GPU, DSP, connectivity), Technology ... and Geography - Forecast and Analysis to 2014-2020", ... & Computing Market is expected to reach $61.70 ... 20.75% from 2014 to 2020. , Browse 71 ...
(Date:7/13/2014)... Seattle, WA (PRWEB) July 13, 2014 ... a longer recovery period from concussions, according to research ... Medicine’s ( AOSSM ) Annual Meeting. The research marks ... to concussion based on the known physical events that ... that patients with a long allele in the (GT)n ...
(Date:7/13/2014)... (PRWEB) July 13, 2014 Fadhits.com is ... sexy prom dresses are extremely beautiful. Recently, the company ... dresses for 2014. What’s more, all these outfits ... percent off). , Additionally, the supplier is now ... with elegant Quinceanera dresses, it has many other designs ...
Breaking Medicine News(10 mins):Health News:Study finds cause of mysterious food allergy, suggests new treatment strategy 2Health News:Study finds cause of mysterious food allergy, suggests new treatment strategy 3Health News:North American Water Storage Systems Market is Expected to Reach $5,450 million by 2018 - New Report by MicroMarket Monitor 2Health News:North American Water Storage Systems Market is Expected to Reach $5,450 million by 2018 - New Report by MicroMarket Monitor 3Health News:Heterogeneous Mobile Processing & Computing Market Worth $61.70 Billion by 2020 – New Report by MarketsandMarkets 2Health News:Heterogeneous Mobile Processing & Computing Market Worth $61.70 Billion by 2020 – New Report by MarketsandMarkets 3Health News:Heterogeneous Mobile Processing & Computing Market Worth $61.70 Billion by 2020 – New Report by MarketsandMarkets 4Health News:Genetic Factors May Be Responsible for Slowing Concussion Recovery in Athletes 2Health News:Fadhits.com Announces a Special Offer on Elegant Quinceanera Dresses 2
... University of Texas Medical Branch at Galveston (UTMB) have found ... cause the “mad cow disease” in people. According to their ... that are there in the blood causing the disease.// ... of Nature Medicine. The findings from the study are expected ...
... syndrome is an endocrine disorder characterized by nervous ... headache and pelvic congestion. ,For the first ... progestin and dosing regimen has been found effective ... the most severe form of premenstrual syndrome. ...
... Ministry of Health is in search of a new cheaper ... Government has reported 200 deaths and 700 patients with infection. ... due to the endemic infection of Encephalitis in Uttar Pradesh. ... 67 patients were admitted in the Government College Hospital in ...
... Dame University have developed unusual antibiotics that have the ... research findings were presented at the 230th national meeting ... society. // ,The new antibiotics are synthetic ... penicillin. They appear to kill bacteria by masquerading as ...
... form of cancer and nearly one out of every three cancers ... the more alarming is that 73% of people with fair skin ... they still get sunburnt despite almost two thirds worrying it could ... is the cause of nearly all types of skin cancer occurring ...
... Chitosan, a dietary supplement used in treating obesity and ... against weight loss. The researcher that had systematically reviewed ... findings in the latest issue of The Cochrane Library.// ... randomized controlled trials that included 1,131 overweight or obese ...
Cached Medicine News:Health News:They Call It PMS Because Mad Cow Disease Was Already Taken 2Health News:Atypical Antibiotics For Super Bugs 2
... therapeutic benefits of controlled compression to minimize ... pain. The cuff is anatomically designed to ... The Ankle Cryo/Cuff is one-size for adults ... size.,All Cryo/Cuffs can be ordered as a ...
SCD Sequential Compression System Intermittent Pneumatic Compression...
Comfor™ Cast Boot - Rocker Sole - Closed Toe...
... cast boot specially lasted for fiberglass ... rocker sole for easy ambulation! ,The ... narrow last so it fits better ... and with our stretchable upper, a ...
Medicine Products: