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Las nuevas guías recomiendan fidaxomicina para todos los pacientes aptos para el tratamiento con antibióticos orales contra la infección por clostridium difficile
Date:10/30/2013

esiva está asociada a un aumento del tiempo de resolución de la diarrea, tasas de curación inferiores y mayor incidencia de recurrencia en pacientes tratados contra la ICD. Los pacientes que residen en centros de cuidados crónicos están especialmente en riesgo y los índices de recurrencia de la ICD pueden ser de hasta el 50 % en un periodo de seis meses si la adquieren en uno de estos centros[17]. Los índices de mortalidad de los pacientes mayores de 65 años ingresados en unidades de cuidados intensivos son de hasta un 45 %[18]. De acuerdo con la guía de tratamiento revisada de la ESCMID, en estas subpoblaciones de pacientes vulnerables se recomienda DIFICLIR para los pacientes aptos para el tratamiento con antibióticos orales.

«La ICD es potencialmente mortal y tiene un gran impacto sobre la salud y la calidad de vida de los pacientes. Esperamos que el cumplimiento de estas recomendaciones nos permita luchar mejor contra la ICD y mejore el tratamiento de la recurrencia», declaró Ken Jones, presidente y consejero delegado de Astellas Pharma Europe Ltd.  

La anterior guía de la ESCMID se publicó en 2009[19] y ha sido ampliamente aplicada en el entorno clínico. Sin embargo, con el desarrollo de nuevos tratamientos contra la ICD, era necesario actualizar este documento para mejorar la uniformidad de las políticas nacionales de tratamiento contra la ICD en los hospitales de toda Europa. Para elaborar guías actualizadas, la ESCMID y un equipo de expertos de 11 países europeos realizaron una búsqueda en la literatura informatizada con el fin de revisar ensayos aleatorizados y no aleatorizados que investigaran el efecto de una intervención sobre el resultado clínico de la ICD. Las guías revisadas de 2013 ofrecen un panorama general de actuales opciones de trata
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SOURCE Astellas Pharma Europe Ltd
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