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Largest Prospective Study Shows IVUS-Guided Stent Placement Improves Patient Outcomes with Current Generation of Stents
Date:11/14/2012

ce changed the therapy in more than two-thirds of the cases, indicating that it helped the interventionalist choose a better and more personalized treatment path for the patient. These results add a robust new plank to the already considerable evidence base supporting IVUS guidance as the standard of care for stent procedures."

One-year results from the ADAPT-DES study—which is designed to determine the frequency, timing and correlates (clinical, angiographic and IVUS) of DES thrombosis and the relationship of aspirin and/or clopidogrel hyporesponsiveness, and general platelet reactivity to early and late DES thrombosis—was reported in a Plenary Session on Thursday, Oct. 25 by Gregg W. Stone, MD, at TCT.

Key Study Results
When compared to procedures without IVUS, IVUS-guided procedures demonstrated a 50% reduction in the incidence of stent thrombosis (a blood clot on the surface of a stent) and 33% reduction in MI that began as soon as 30 days post procedure, and continued for 12 months.

No safety issues were identified in the IVUS-guided procedures in the trial, as there was no increase in peri-procedural MI. IVUS cases were not associated with a significant increase in the usage of stents. The majority of stents used in this study were of the latest generation and marketed globally.

"The ADAPT-DES IVUS results at 30 days and 12 months meaningfully advance the field of interventional cardiology, and also have important implications for the healthcare delivery system as institutions seek strategies to improve the quality of care and avoid penalties imposed by the new CMS 30-day readmission policy," said Scott Huennekens, President and Chief Executive Officer, Volcano Corporation. "With the insight our technologies such as IVUS provide, Volcano can help physicians and healthcare institutions answer the growing demand for truly personalized medicine that is appropriate, evidence-based and accountable."

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SOURCE Volcano Corporation
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