Navigation Links
Largest Multi-Centre Evaluation of Radioembolization Using Sir-Spheres for Patients With Inoperable Primary Liver Cancer Published in Hepatology
Date:7/7/2011

y on the state of their liver at the time of their diagnosis and the extent of tumour invasion.

Findings of the ENRY Evaluation

The majority of the patients (82.5%) evaluated by the ENRY group had liver disease that was reasonably-well compensated (Child-Pugh class A), with underlying cirrhosis (78.5%) and good ECOG Performance status (ECOG 0-1: 87.7%).  However, many of them had multiple tumour nodes (75.9%), with disease present in both lobes of the liver (53.1%) and/or occlusion of the portal vein (the vessel that transports blood from the gastrointestinal tract to the liver) in either a branch of the vein (13.5%) or the main vessel (9.8%).

Over 40 per cent of the patients (41.5%) had progressed following one or more other treatments prior to receiving radioembolization with SIR-Spheres (yttrium-90 resin microspheres; Sirtex Medical Limited, Sydney, Australia), including surgery or liver transplantation, percutaneous procedures such as ethanol injection or radiofrequency ablation of individual liver tumours, or vascular procedures such as transarterial embolisation (TAE) or chemoembolisation (TACE) that block the liver arteries that feed tumours.

Using Barcelona Clinic Liver Cancer (BCLC) staging criteria, the vast majority of patients evaluated by the ENRY group had either advanced (BCLC C: 56.3%) or intermediate (BCLC B: 26.8%) disease.

The patients who received radioembolization (also called selective internal radiation therapy or SIRT) were administered a median dose of 1.6 GBq of beta-radiating yttrium-90 resin microspheres, predominately as a single procedure delivered transarterially to the liver via a catheter through the femoral and hepatic arteries.  The median overall survival of the SIRT-treated patients evaluated by the ENRY group was 12.8 months.  Survival varied significantly by disease stage: 24.4 months for patients in BCLC A; 16.9 months in BCLC B; and 10.0 months in BCLC C.  

"As ENR
'/>"/>

SOURCE ENRY Trialists
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Georgia Reproductive Specialists Participates in Largest-Ever In Vitro Fertilization Clinical Trial in the World
2. Largest Study to Date Shows Significant Reductions in Risks of Blood Clots and Reintervention With CYPHER(R) Sirolimus-eluting Coronary Stent Compared to Taxus Stent
3. International Expert Group Initiates Largest Multi-center Phase III Trial to Evaluate NeuroAid(TM) in Stroke Recovery
4. Video: The Arizona Heart Institute Announces the Largest Worldwide Experience with Endoluminal Grafting to Treat Thoracic Aortic Aneurysms and Related Pathologies
5. Raydiance Collaborates With Rutgers University and Nations Largest Tissue Bank to Develop Innovative Tissue Processing Approaches
6. Video: New Results From One of the Worlds Largest Breast Cancer Trials Herald Hope for Thousands of Women
7. Universite de Montreal Researchers Simulate Worlds Largest Heart Model Using SGI Technology
8. Boehringer Ingelheim Announces Enrollment is Complete for the Largest Atrial Fibrillation Outcomes Trial - The RE-LY(TM) Study
9. Safety and Efficacy Results Presented From Largest Prospective Controlled Clinical Study of Ulcerative Colitis
10. The Largest Ever Study of Diabetes Shows Intensive Glucose Control Reduces Serious Complications
11. Study Published in Journal of Clinical Psychiatry Showed Once-Daily VYVANSE(R) (lisdexamfetamine dimesylate) Significantly Improved ADHD Symptoms in One of the Largest Controlled Stimulant Trials in Adults with ADHD
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/30/2014)... September 30, 2014 In a ... (Cerebrospinal Fluid) backflow of the Eldor spinal needle 25G, ... single hole pencil point spinal needles of the same ... Spinal anesthesia is an excellent type of regional ... General Anesthesia, etc. It is estimated that ...
(Date:9/30/2014)... MUNSTER, Ind. , Sept. 30, 2014  The orthopedic ... ranked the nation,s No. 6 orthopedic group by US ... for Active Adults," a series of free, public seminars ... from all over the world come to see the ... replacement procedures are now available at Munster Specialty Surgery ...
(Date:9/30/2014)... Sept. 30, 2014  Arena Solutions, the pioneer ... announced its Fall 2014 release, which includes two ... Arena DataExtract – and significant enhancements ... products are focused specifically on speeding time to ... of a complete history of tribal knowledge throughout ...
Breaking Medicine Technology:"Knee Pain Solutions for Active Adults" Complimentary Seminars Open to the Public 2Arena Unveils Unique PLM Collaboration Platform And New Data Extraction Tool 2Arena Unveils Unique PLM Collaboration Platform And New Data Extraction Tool 3Arena Unveils Unique PLM Collaboration Platform And New Data Extraction Tool 4
... governmental markets still depressed, Allied Healthcare Products (Nasdaq: AHPI ... year 2011 and improvement in its year-over-year performance. ... 1 cent per basic and diluted share, compared to $22,000, or ... first two quarters of the fiscal year, net income was about ...
... Feb. 8, 2011 Actavis Group, an international generic ... from the US Food & Drug Administration to market ... will commence shortly.   Pantoprazole Sodium Delayed-Release ... 20mg and 40mg by Pfizer, had US sales of ...
Cached Medicine Technology:Allied Healthcare Products Reports Modest Profit for Quarter 2Allied Healthcare Products Reports Modest Profit for Quarter 3Allied Healthcare Products Reports Modest Profit for Quarter 4Actavis Receives Approval of Pantoprazole Sodium Delayed-Release Tablets, USP in the U.S. 2
(Date:9/30/2014)... -- There,s no genetic evidence that high levels of ... study says. Some previous research had suggested that ... type 2 diabetes, raising the possibility of a link ... In this study, British researchers investigated the association ... genes that control blood levels of vitamin D. They ...
(Date:9/30/2014)... HealthDay Reporter TUESDAY, Sept. 30, ... to put the brakes on motherhood. And for many young ... choice, new research suggests. Women in their early 20s ... during tough economic times. But, according to the new study, ... their 40s and beyond. The findings suggest that higher ...
(Date:9/30/2014)... Health Day Reporter TUESDAY, Sept. ... are overweight or obese when diagnosed appear to face ... cancer, new research suggests. , , The finding didn,t ... the potential for developing other cancers associated with obesity. ... reported being overweight or obese prior to diagnosis had ...
(Date:9/30/2014)... PROVIDENCE, R.I. [Brown University] Autism is no stranger ... the East African nation is access to clinical services, ... autism diagnostic measure, for example, validated for use in ... small new study, however, researchers at Brown University and ... diagnostic approach that they implemented at two sites in ...
(Date:9/30/2014)... (PRWEB) September 30, 2014 A new ... State University studied the impact of stress on metabolism after ... and french fries from a fast food restaurant, about 930 ... resting metabolism for 20 minutes every hour for 7 hours, ... showed that women who had experienced a stressful event in ...
Breaking Medicine News(10 mins):Health News:Gene Study Finds No Proof Vitamin D Guards Against Type 2 Diabetes 2Health News:Recessions May Thwart a Woman's Motherhood Plans Forever: Study 2Health News:Recessions May Thwart a Woman's Motherhood Plans Forever: Study 3Health News:Obesity Tied to Higher Cancer Risk for Colon Cancer Survivors 2Health News:Obesity Tied to Higher Cancer Risk for Colon Cancer Survivors 3Health News:New diagnostic approach for autism in Tanzania 2Health News:New diagnostic approach for autism in Tanzania 3Health News:New diagnostic approach for autism in Tanzania 4Health News:NutriGold Urges Every Woman To Read a Recent Study About Diet and Stress 2Health News:NutriGold Urges Every Woman To Read a Recent Study About Diet and Stress 3
... Medicine researchers have found that intensively controlling glucose (glycemic) levels ... kidney failure. The study, which is a review of data ... issue of Archives of Internal Medicine . ... renal disease in patients with type 2 diabetes mellitus, first ...
... should enable them to detect signs of a disease in ... Nature Materials . The scientists, from Imperial ... test to detect particular molecules that indicate the presence of ... are already tests available for some diseases that look for ...
... Americans with individual market health insurance coverage in 2010 were ... the lowest "bronze"-level plans in the Affordable Care Act, and ... health insurance exchanges that are being created under the law, ... Web First in the journal Health Affairs . The ...
... Reporter , FRIDAY, May 25 (HealthDay News) -- Doctors have ... relief in physical pain -- cutting or burning or sticking ... But researchers now are questioning whether enough is being done ... before they do themselves irreparable damage. One study this ...
... its epidermal growth factor receptor cousins mobilize a specialized protein ... metabolism, scientists report in the May 25 issue of ... promotes Herceptin resistance in breast cancer and activation of glucose ... their growth and survive. Their research focused on Skp2 ...
... 25 (HealthDay News) -- Exposure to loud music at a ... researchers say. A small study by the House ... hearing after attending a three-hour show. This type of hearing ... repeatedly, permanent hearing loss can develop, the study authors noted. ...
Cached Medicine News:Health News:Super-sensitive tests could detect diseases earlier 2Health News:Half of Americans with individual health plans could gain better coverage under the ACA 2Health News:Half of Americans with individual health plans could gain better coverage under the ACA 3Health News:Half of Americans with individual health plans could gain better coverage under the ACA 4Health News:More Mental Health Care Urged for Kids Who Self-Harm 2Health News:More Mental Health Care Urged for Kids Who Self-Harm 3Health News:Skp2 activates cancer-promoting, glucose-processing Akt 2Health News:Skp2 activates cancer-promoting, glucose-processing Akt 3Health News:Can You Hear Me Now? 2
... spectrophotometer designed specifically to run 24 hours ... rugged hardware, proven optical performance and a ... traditional spectrophotometry to obtain results quickly, accurately ... up to eight, 1 cm Biocell cuvettes ...
The PerkinElmer LS 45 Luminescence spectrometer offers versatility, reliability and ease-of-use for routine analyses in an affordable package....
... a new generation Spectrophotometer for near ... nm to 1020 nm with built-in ... and printer. It features four digit ... transmittance, absorption and concentration with excellent ...
... UV/visible spectrophotometers provide ease-of-use and proven technology ... DU Series 800 high-performance spectrophotometers with microfocused ... as small as 5 l. The DU ... intended for use in quantitative and qualitative ...
Medicine Products: