Large Controlled Trial of Widely Used Mood Stabilizers Demonstrates Efficacy in Pediatric Bipola...(hts distractibility that varies with moo...),Health

Date:10/26/2007

hts, distractibility that varies with mood, increased goal-directed activity, hypersexuality and, in some cases, hallucinations. Children with the illness are at increased risk of attempting suicide. Bipolar disorder, like epilepsy, tends to be a lifelong mecial condition that can be managed with medication, psychotherapy and lifestyle changes such as stress reduction, regular sleep, accommodations at school and avoidance of caffeine, alcohol and drugs of abuse.

Dr. Kowatch is an internationally known expert for his research in child and adolescent bipolar disorders. In 2005, he organized and published the now current national treatment guidelines for bipolar I disorder on behalf of the Child & Adolescent Bipolar Foundation. The guidelines appeared in the March 2005 Journal of the American Academy of Child and Adolescent Psychiatry. The recommendations are based on evidence from research studies done in children and adults, case reports published in medical journals, and consensus by a group of experts as to current clinical practices. Further information about pediatric bipolar disorder can be found at http://www.cincinnatichildrens.org/health/info/mental/diagnose/manic.htm.

At a Glance:

-- Largest pediatric study of its kind with mood stabilizers demonstrates

efficacy for significantly improving symptoms of bipolar I disorder

-- First controlled trial to test and compare lithium and divalproex

versus placebo for six months, largest trial of lithium and divalproex

to date and first to demonstrate efficacy for divalproex in children

aged 7 to 17 years, diagnosed with bipolar I disorder, mixed or manic.

Cincinnati Children's Hospital Medical Center, one of the leading pediatric research institutions in the nation, is dedicated to changing the outcome for children throughout the world. Cincinnati Childre
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SOURCE Cincinnati Children's Hospital Medical Center Copyright©2007 PR Newswire. All rights reserved

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