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Lantus®/Apidra® SoloSTAR® Help to Improve Patient Satisfaction
Date:6/26/2011

PARIS, June 27, 2011 /PRNewswire/ --


 

Sanofi (EURONEXT: SAN and NYSE: SNY) announced today, at the 71st Scientific American Diabetes Association Sessions 2011, the results of three studies showing that people with diabetes using Sanofi insulins Lantus® and/or Apidra® with the insulin delivery device SoloSTAR® experienced greater treatment satisfaction, better quality of life and lower fear of hypoglycemia vs those using a premixed insulin product.

The goal of the first study[1], involving 586 patients with uncontrolled type 2 diabetes on oral agents, was to evaluate any changes in physical and psychological well-being, diabetes-related symptoms, and patient satisfaction with diabetes-related care and treatment over the study period and from baseline to endpoint.

It showed that, compared with those on twice-daily premixed 70/30 insulin aspart (premix), patients on the combination of Lantus®- and Apidra®-based regimens experienced better quality of life as measured by the Diabetes Quality of Life (DQoL) questionnaire, which evaluates personal perception of improvements as a result of treatment:

  • DQoL improved significantly for all groups at all wks; average improvement was greater for basal Lantus® (insulin glargine) + 1 prandial Apidra® (insulin glulisine) dose (GLARG+1) and stepwise addition of prandial glulisine (GLARG+0-3) vs premix (P≤0.0002)
  • Compared to the glargine group, patients on premix also showed significantly greater hypoglycemic fear from week 12 to study end (P<0.05).

The goal of the second study[2], conducted with 220 type 1 and type 2 patients from 32 sites in Canada, was to evaluate the change in diabetes t
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