Landscape for Lung Cancer Therapies is Focus of New Post-ASCO MedPred... ( SCOTTSDALE Ariz. June 26 /- MedPr...)

Landscape for Lung Cancer Therapies is Focus of New Post-ASCO MedPredict Report

Date:6/26/2008

SCOTTSDALE, Ariz., June 26 /PRNewswire/ -- MedPredict has published a new report in its oncology series entitled "Thought Leader Insight & Analysis: Lung Cancer," designed to provide critical strategic insight for pharma and biotech companies with a stake in the market for diagnostics and treatments in non-small cell and small cell lung cancer.

The big news at the recent American Society of Clinical Oncology (ASCO) meeting was the presentation of the Erbitux FLEX clinical trial data showing increased overall survival in EGFR-positive first-line non-small cell lung cancer. In light of these positive results, MedPredict's panel addresses the following questions: Is Erbitux useful in those 40% of patients who are Avastin-ineligible? Is Erbitux useful in the 24% patients who aren't getting Avastin but in theory could? Is Erbitux going to legitimately threaten Avastin in an Avastin-eligible patient?

MedPredict's panel also reviews recent advances in other mechanistic approaches to treatment, including angiogenesis/VEGF, vascular disrupting agents, anthracyclines, TRAIL / DR4 / DR5, Bcl-2/Bcl-xL, survivin, cyclin dependent kinase, cMET, EGFR (T790M), antifolate, HDAC / epigenetics, Hedgehog, HSP90, IGF-1, MAGE-A3, MEK, microtubule, apoptosis, kinesin/EG5, aurora kinase, Polo-like kinase 1, mTOR, PI3/AKT, KRAS, and topoisomerase.

"This report will provide essential strategic insight for those involved in development of lung cancer therapies," according to MedPredict President Dr. Jeffrey Berk. "Our panelists discuss ongoing clinical programs, and offer their opinions on which of the myriad new drugs in development are likely to be significant improvements over current options."

Some of the companies/partnerships discussed in this report include: Abbott, Abraxis, Amgen, Angiogene, Antisoma, Ardea, Array, Ascenta, AstraZeneca, Bayer-Schering, Bristol-Myers Squibb, Boehringer Ingelheim, Concordia, Critical Outcome Technologies, Cytokinetics,
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