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Landmark study of more than 27,000 women shows favorable results of Roche's CINtec PLUS cytology test
Date:11/4/2013

ec PLUS test with HPV DNA testing would make a lot of sense."

More than 500,000 new cases of cervical cancer are diagnosed each year worldwide.2 Disappointingly, the average five-year survival rate of patients is only around 50%.2 HPV infections are common and cause virtually all cervical cancer.2  However, only those women with persistent HPV infections and who have developed high-grade precancerous cervical disease should be treated. The CINtec PLUS cytology test was developed to help identify those HPV infections that may lead to cancer and distinguish them from those that will not.

The authors (Safaeian and Sherman) of an editorial published along with the PALMS study results write that dual biomarker screening could have a role in primary screening, especially in younger women. They also conclude that the dual assay could serve as a triage for positive HPV tests and could dramatically decrease patient referrals to colposcopy and other invasive and costly procedures unnecessarily.

"The results demonstrated in the PALMS trial reinforces the medical value Roche brings to cervical cancer screening.  We are committed to improving patient outcomes by providing differentiated diagnostic tools for doctors and laboratories," says Mara G. Aspinall, President, Ventana Medical Systems, Inc.  "We are pleased to announce that a fully automated version of the CINtec® PLUS cytology test will be launching later this year and will join the cobas® HPV test and the CINtec® Histology test to complete our portfolio of cervical cancer screening products."

*The CINtec® PLUS cytology test is not available in all geographies and/or may not be approved for all uses discussed in this press release.

1JNCI – The Journal of the National Cancer Institute (Ikenberg et al. Screening for Cervical Cancer Precursor
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SOURCE Ventana Medical Systems, Inc.
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