Navigation Links
Landmark ONTARGET(TM) Trial Demonstrates Micardis(R) is Equally Effective as Ramipril, with Fewer Discontinuations, in a Broad High-Risk Cardiovascular Population
Date:3/31/2008

Results of ONTARGET (ONgoing Telmisartan Alone and in combination with Ramipril Global Endpoint Trial) involving 25,620 patients presented today at the 57th Annual Scientific Session of the American College of Cardiology

and published online in the New England Journal of Medicine

CHICAGO, March 31 /PRNewswire/ -- The results of the landmark ONTARGET(TM) trial have demonstrated that MICARDIS(R) (telmisartan), a second-generation angiotensin II receptor blocker (ARB), is equally effective as the current standard, ramipril, in reducing the risk of cardiovascular death, myocardial infarction, stroke and hospitalization for congestive heart failure in a broad cross-section of high-risk cardiovascular patients with normal blood pressure or controlled high blood pressure, and resulted in fewer discontinuations.(1) These cardiovascular events occurred in 1,423 patients (16.7 percent) receiving telmisartan versus 1,412 patients (16.5 percent) receiving ramipril.(1) The relative risk (ratio of the probability of the event occurring in the telmisartan group versus the ramipril group) was 1.01, with a 95 percent CI of 0.94 - 1.09.

Telmisartan is now the only ARB to have demonstrated cardio and vascular risk reduction benefits beyond lowering blood pressure in this high-risk population;(1) these benefits may be attributed to the specific pharmacological properties and mode of action of the drug. Previously, in 2000, the HOPE trial showed that the cardiovascular risk for patients treated with the angiotensin-converting enzyme (ACE) inhibitor ramipril was reduced by approximately 20 percent compared with placebo.(2) This meant that every fifth serious cardiovascular event in a high risk group of patients was prevented.(2)

"The ONTARGET trial shows that telmisartan is a well-tolerated treatment in high-risk cardiovascular patients that is as effective as ramipril in preventing heart attacks, stroke and hospitalizations for heart failure and dea
'/>"/>

SOURCE Boehringer Ingelheim Pharmaceuticals, Inc.
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6 7

Related medicine technology :

1. Video: Landmark Study in The Lancet: Patients Treated With Betaseron(R) After First MS Attack Experienced Significant Delay in MS Progression
2. Viatronix V3D-Colon Utilized in Another Landmark Study
3. Long-Term Data from a Landmark Phase III Trial Show Survival Benefit at Three- and Four-Years in Patients with Glioblastoma multiforme
4. Hospital Launches Landmark Emergency Medicine Project
5. JACC Identifies DEFER with 5-year Outcomes as Landmark Trial
6. Progen Engages Leading CRO to Assist with Phase 3 Trial of PI-88
7. Auxilium Pharmaceuticals, Inc. Receives Clearance to Resume Clinical Trials for XIAFLEX(TM)
8. Romark Initiates Clinical Trial of Alinia(R) for Chronic Hepatitis C in the United States
9. The Multiple Myeloma Research Consortium (MMRC) and Proteolix Initiate Phase 2 Clinical Trial Investigating Carfilzomib for the Treatment of Multiple Myeloma
10. Millennium Initiates Clinical Trial to EVOLVE the Treatment of Patients with Newly Diagnosed Multiple Myeloma
11. Vion Pharmaceuticals Completes Accrual of 85 Patients to its Pivotal Phase II Trial of Cloretazine(R) (VNP40101M) in Elderly AML
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/30/2015)... , July 30, 2015  Amgen (NASDAQ: AMGN ... partner and managing director of Warburg Pincus LLC, to the ... to welcome Fred Hassan and the deep, global ... Board," said Robert A. Bradway , chairman and chief ... to innovation will serve Amgen well." Mr. Hassan ...
(Date:7/30/2015)... LAKE, N.J. , July 30, 2015 ... simultaneously in the United States , ... the FDA, EMA and MHLW, respectively) for eribulin, for ... (STS) who have received prior chemotherapy for advanced or ... based on data from a pivotal global Phase 3 ...
(Date:7/30/2015)... YORK , July 30, 2015 /PRNewswire/ ... a new research report with market overview, ... share, forecast, porter analysis, recent developments, competitive ... Global Industry Insight: Biosensors Market Development ...      (Logo: http://photos.prnewswire.com/prnh/20150727/756778 ) ...
Breaking Medicine Technology:Amgen Announces Appointment Of Fred Hassan To Board Of Directors 2Amgen Announces Appointment Of Fred Hassan To Board Of Directors 3Eisai Submits Simultaneous Regulatory Applications for Eribulin in Soft Tissue Sarcoma in the United States, European Union and Japan 2Eisai Submits Simultaneous Regulatory Applications for Eribulin in Soft Tissue Sarcoma in the United States, European Union and Japan 3Eisai Submits Simultaneous Regulatory Applications for Eribulin in Soft Tissue Sarcoma in the United States, European Union and Japan 4Eisai Submits Simultaneous Regulatory Applications for Eribulin in Soft Tissue Sarcoma in the United States, European Union and Japan 5Global Biosensors Market (Size of $12,964 Million in 2014) to Witness 10% CAGR During 2015 - 2020 2Global Biosensors Market (Size of $12,964 Million in 2014) to Witness 10% CAGR During 2015 - 2020 3Global Biosensors Market (Size of $12,964 Million in 2014) to Witness 10% CAGR During 2015 - 2020 4Global Biosensors Market (Size of $12,964 Million in 2014) to Witness 10% CAGR During 2015 - 2020 5
(Date:7/31/2015)... ... July 31, 2015 , ... Coco Libre announced today that their flagship ... at the 2015 Vans US Open of Surfing, July 25 through August 2 in ... added sugar” on the market, is a natural choice given the Open’s commitment to ...
(Date:7/31/2015)... ... 2015 , ... According to an article published July 2 on ... reach a consensus on the steps that need to be taken to successfully complete ... percent consensus on a series of steps that each surgeon must complete for each ...
(Date:7/31/2015)... ... July 31, 2015 , ... As part of their company mission, ... of animal welfare organizations is essential to the longevity of their business. It ... National Association of Professional Pet Sitters (NAPPS) annual Presents 4 Pets supply drive. ...
(Date:7/31/2015)... MA (PRWEB) , ... July 31, 2015 , ... ... this year’s “HARMONY 2015”, one of the industry’s premier thought leadership symposiums, ... November 5 and 6. The event attracts over 250 “C”-level executives, administrators, ...
(Date:7/31/2015)... ... July 31, 2015 , ... The 2015 ALS Ice Bucket Challenge will ... the Boston Red Sox honor Ice Bucket co-founders Pat Quinn and Pete Frates, the ... to further collaborative efforts among the ALS organizations to find treatments and cures for ...
Breaking Medicine News(10 mins):Health News:Coco Libre Brings Eco-conscious Hydration to Vans US Open of Surfing 2Health News:Article on Plastic Surgery Consensus Highlights the Duties of Veteran Plastic Surgeons, says Beverly Hills Physicians 2Health News:Article on Plastic Surgery Consensus Highlights the Duties of Veteran Plastic Surgeons, says Beverly Hills Physicians 3Health News:Dallas-based Park Cities Pet Sitter Selects Non-Profit Animal Welfare Organization “Angie’s Friends” as this Year’s Recipient of their Presents 4 Pets Supply Drive. 2Health News:Dallas-based Park Cities Pet Sitter Selects Non-Profit Animal Welfare Organization “Angie’s Friends” as this Year’s Recipient of their Presents 4 Pets Supply Drive. 3Health News:Dallas-based Park Cities Pet Sitter Selects Non-Profit Animal Welfare Organization “Angie’s Friends” as this Year’s Recipient of their Presents 4 Pets Supply Drive. 4Health News:Harmony Healthcare International Announces Speaker Line-up for “HARMONY 2015” 2Health News:Harmony Healthcare International Announces Speaker Line-up for “HARMONY 2015” 3Health News:Major League Baseball Joins MDA and Fourteen Other ALS Organizations to Launch ALS Ice Bucket Challenge 2015 2Health News:Major League Baseball Joins MDA and Fourteen Other ALS Organizations to Launch ALS Ice Bucket Challenge 2015 3Health News:Major League Baseball Joins MDA and Fourteen Other ALS Organizations to Launch ALS Ice Bucket Challenge 2015 4
... Efforts Stumble, Millions Remain Without AIDS Treatment ... ... in,two weeks, clinical researchers working to develop an AIDS vaccine have,announced that ... -- after Merck,s AIDS vaccine trial was halted last week,when its vaccine ...
... Among Top 50 Pharma To Offer, Competitively ... SAN DIEGO, Nov. 15 Image Solutions, ... to streamline the drug,development and regulatory approval process, ... solutions and services to emerging,and mid-market life sciences ...
... for Radiologists, COEUR D,ALENE, Idaho, Nov. 15 ... the leading provider of services,to radiology groups across ... offering its full range of services, an industry ... Annual Meeting (North Building,- Hall B: 8551) in ...
... More than 1.4 million Americans live in nursing homes ... long-term care, whether in a nursing home, assisted living ... service provider. , At this time of skyrocketing demand ... awarded Brown University a major grant to create the ...
... Nov. 15 BioHorizons Implant Systems,Inc. has introduced ... feature a,unique thread design and proven surface engineering ... to address the tapered,market segment which account for ... The Tapered Internal Implants incorporate the Laser-Lok(R) precision,laser ...
... Digital,s Medical Director for ... Ophthalmology, WAKE FOREST, ... retinal risk assessment for diabetics,announced today that Suber S. Huang, MD, MBA ... expert,advice and counsel regarding product development and development. Dr. Huang is ...
Cached Medicine News:Health News:AIDS Vaccine Failures Highlight Need to Focus on Lifesaving Treatment, Says AHF 2Health News:ISI Announces Expansion of Mid-Market Life Science Compliance Solutions at DIA eCTD Conference 2Health News:ISI Announces Expansion of Mid-Market Life Science Compliance Solutions at DIA eCTD Conference 3Health News:ISI Announces Expansion of Mid-Market Life Science Compliance Solutions at DIA eCTD Conference 4Health News:NightHawk Radiology: One Source, One Solution 2Health News:NightHawk Radiology: One Source, One Solution 3Health News:NightHawk Radiology: One Source, One Solution 4Health News:Brown to create most comprehensive long-term care database 2Health News:Brown to create most comprehensive long-term care database 3Health News:BioHorizons Introduces Its New Tapered Internal Implants Featuring Laser-Lok(R) Microgrooves 2Health News:Digital Healthcare Announces Appointment of Dr. Suber Huang as Medical Director 2Health News:Digital Healthcare Announces Appointment of Dr. Suber Huang as Medical Director 3
... Biosense Webster offers a complete line ... Fixed Catheter is designed for simple ... coronary sinus. The pair of electrodes ... permit pacing in the coronary sinus ...
... the source for a complete line of ... left-sided mapping - all with the quality, ... expect from the leader in catheter technology. ... catheters are specifically designed and constructed to ...
... Torqr Quadripolar Braided ... The Medtronic CardioRhythm ... for use in diagnostic ... is designed for recording ...
... Soft HIS diagnostic catheters provide ... designed curve that allows for ... HIS bundle. In addition, the ... reduce the risk of perforation ...
Medicine Products: