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Lamotrigine is One of the Most Commonly Prescribed Drugs Among Newly Diagnosed Bipolar Disorder Patients in the United States
Date:10/23/2013

BURLINGTON, Mass., Oct. 23, 2013 /PRNewswire/ -- Decision Resources, one of the world's leading research and advisory firms for pharmaceutical and healthcare issues, finds that, through analysis of U.S. longitudinal patient-level claims data, antiepileptic drugs (AEDs), atypical antipsychotics and selective serotonin reuptake inhibitors capture the largest patient shares among all therapies assessed in newly diagnosed bipolar disorder patients across all three lines of therapy. Although no single agent from any of these drug classes was shown to dominate first-line treatment of newly diagnosed bipolar disorder patients, the AED lamotrigine (GlaxoSmithKline's Lamictal, generics) led other individual agents with nearly 20 percent of first-line patient share. According to thought leaders interviewed by Decision Resources, lamotrigine is considered to be beneficial for preventing and treating bipolar depression, one of the more challenging aspects of treating bipolar disorder.

The report Treatment Algorithms in Bipolar Disorder finds that among newly diagnosed patients, Abilify (Bristol-Myers Squibb/Otsuka) captured the highest first-line patient share within the atypical antipsychotic drug class, despite the availability of multiple generically available agents. Abilify's high patient share among agents in this class is likely due to relatively favorable reimbursement status, a more favorable tolerability profile than other atypical antipsychotics and approval to treat multiple psychiatric indications, which can contribute to physician awareness and preference.

The report also finds that, together, quetiapine products (AstraZeneca's Seroquel, generics and AstraZeneca's Seroquel XR) claimed the highest percentage of patient share within the atypical antipsychotic class among recently treated bipolar disorder patients. Combined,
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SOURCE Decision Resources
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