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Lakewood-Amedex Announces Results Demonstrating The More Rapid Direct Bactericidal Activity Of Novel Bisphosphocin Class Of Antimicrobials
Date:5/16/2013

tance and increasing their potency when bacteria become dormant or form a biofilm. 

Lakewood-Amedex's Vice President, Product Development, Paul DiTullio , commented "The recent studies using Nu-3 provide further confirmation of the major advantages offered by the bisphosphocin class for the treatment of bacterial and fungal infections and their potential to address several major healthcare problems."

The Company is fast tracking the development of a topical bisphosphocin formulation specifically because its rapid bactericidal activity makes it an excellent therapeutic candidate to address several unmet medical needs for clinical indications such as acute bacterial skin infection, infected diabetic foot ulcer, ophthalmic infections, and fungal infections such as onychomycosis.  In addition, bisphosphocins exhibit an extremely broad spectrum of activity that is critical when addressing clinical indications where the infection may be polymicrobial, or with eye infections where there is no time to identify the infecting organism.  The compounds possess an excellent safety profile and are well tolerated in vivo due to their highly specific mechanism of action that exploits a critical difference between the prokaryotic membranes of bacteria/fungi and the eukaryotic membranes of mammals, including humans. 

Lakewood-Amedex expects to make additional major announcements regarding the utility of the bisphosphocin family of broad-spectrum antimicrobials in the coming weeks and is actively seeking partnering opportunities for major indications using these products.

About Lakewood-Amedex, Inc.

Lakewood-Amedex is a privately held biopharmaceutical company developing a broad portfolio of anti-infective products, including first-in-class anti-bacterial compounds, orally available nanoRNA therapeutics for acute and chronic diseases such as arthritis, inflammation, cancer, influenza, and he
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SOURCE Lakewood-Amedex Inc.
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