Navigation Links
LX2931 Phase 2 Data to be Presented at the American College of Rheumatology Conference
Date:11/9/2011

THE WOODLANDS, Texas, Nov. 9, 2011 /PRNewswire/ -- Lexicon Pharmaceuticals, Inc. (Nasdaq: LXRX), a biopharmaceutical company focused on discovering breakthrough treatments for human disease, announced today that Dr. Roy Fleischmann from the University of Texas Southwestern Medical Center will be presenting data from Lexicon's LX2931 Phase 2 proof-of-concept clinical trial at the annual meeting of the American College of Rheumatology on Wednesday, November 9, 2011 in Chicago, Illinois.  LX2931 is an orally-administered small molecule designed to inhibit sphingosine-1-phosphate lyase (S1P), an enzyme in a pathway known to be important in regulating the immune response.  

Results from the Phase 2a study demonstrated a favorable safety profile at all doses tested and suggested that patients with rheumatoid arthritis treated with 150 mg of LX2931 once daily showed improvement in the primary efficacy endpoint of the study, the percentage of patients achieving an American College of Rheumatology 20 (ACR20) response at week 12.

For more information on this program or to download a copy of the presentation, please visit www.lexpharma.com.

About Lexicon

Lexicon is a biopharmaceutical company focused on discovering breakthrough treatments for human disease.  Lexicon currently has four drug programs in mid-stage development for diabetes, irritable bowel syndrome, carcinoid syndrome and rheumatoid arthritis, all of which were discovered by Lexicon's research team.  Lexicon has used its proprietary gene knockout technology to identify more than 100 promising drug targets.  Lexicon has focused drug discovery efforts on these biologically-validated targets to create its extensive pipeline
'/>"/>

SOURCE Lexicon Pharmaceuticals, Inc.
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Lexicon Announces Top-Line Phase 2a Data for LX2931 in Patients with Rheumatoid Arthritis
2. Lexicon Files Investigational New Drug Application for LX2931 as a Potential Treatment for Rheumatoid Arthritis
3. ChemoCentryx Reports Clinical Efficacy for CCX354, a Novel CCR1 Inhibitor in a Phase II Study in Patients with Rheumatoid Arthritis
4. Sustained Viral Response from Phase 2 Studies of BI 201335, Including Difficult-to-Treat HCV Patient Types
5. Positive Interim Results from Interferon-Free Phase 2b SOUND-C2 Study with Boehringer Ingelheims Two Investigational HCV Direct Acting Antivirals Presented at AASLD
6. Tibotec to Present Final Safety and Efficacy Results From Phase 2b PILLAR Study of Once-Daily TMC435 in Late-Breaker at AASLD
7. Qnexa® Phase 3 Data Published In Obesity Show 14.4% Average Weight Loss In Severely Obese Patients Completing One Year Of Treatment
8. Isis Initiates Phase 1 Studies with Isis-GCGRRx and Isis-GCCRRx to Treat Type 2 Diabetes
9. Pharmasset Announces the Initiation of an Interferon-Free Phase 3 Program with PSI-7977 for HCV
10. Inovio Pharmaceuticals Cervical Dysplasia And Cancer Treatment Highlighted as One of 10 Promising Therapeutic Vaccines; Phase II Clinical Study Currently Enrolling
11. Cytogel Pharma, LLC. Announces Presentation at the American Society of Anesthesiologists meeting in Chicago on October 18, 2011, Describing Results From its First Human Study, Part of the Phase I Program for Cyt-1010
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:1/15/2014)... Ill. , Jan. 15, 2014 The Cadence ... Medical Fitness Center by the Medical Fitness Association, a ... to achieve their full potential. The Cadence Fitness & ... the western suburbs and second in the Chicagoland area. ...
(Date:1/15/2014)... NEW YORK , Jan. 15, 2014 ... research report is available in its catalogue: ... & Forecast – Worldwide Analysis ... Pump Market Analysis ...
(Date:1/15/2014)... Quebec , Jan. 15, 2014  Valeant Pharmaceuticals International, ... announced that the applicable waiting period under the Hart-Scott-Rodino ... the previously announced tender offer by its indirect wholly-owned ... outstanding shares of common stock of Solta Medical, Inc. ...
Breaking Medicine Technology:Cadence Fitness & Health Center Certified as Medical Fitness Facility 2Cadence Fitness & Health Center Certified as Medical Fitness Facility 3Insulin Pump Market & Forecast - Worldwide Analysis 2Insulin Pump Market & Forecast - Worldwide Analysis 3Insulin Pump Market & Forecast - Worldwide Analysis 4Insulin Pump Market & Forecast - Worldwide Analysis 5Insulin Pump Market & Forecast - Worldwide Analysis 6Insulin Pump Market & Forecast - Worldwide Analysis 7Insulin Pump Market & Forecast - Worldwide Analysis 8Insulin Pump Market & Forecast - Worldwide Analysis 9Insulin Pump Market & Forecast - Worldwide Analysis 10Insulin Pump Market & Forecast - Worldwide Analysis 11Insulin Pump Market & Forecast - Worldwide Analysis 12Insulin Pump Market & Forecast - Worldwide Analysis 13Insulin Pump Market & Forecast - Worldwide Analysis 14Insulin Pump Market & Forecast - Worldwide Analysis 15Insulin Pump Market & Forecast - Worldwide Analysis 16Insulin Pump Market & Forecast - Worldwide Analysis 17Valeant Pharmaceuticals Announces Receipt Of Antitrust Clearance For Its Previously Announced Acquisition Of Solta Medical, Inc. 2Valeant Pharmaceuticals Announces Receipt Of Antitrust Clearance For Its Previously Announced Acquisition Of Solta Medical, Inc. 3
... (Nasdaq: ENDP ) today announced the successful completion ... West Acquisition Corp., for all of the outstanding shares of ... American Stock Transfer & Trust Company, the depositary for the ... New York City time, on Sept. 17, 2010, the expiration ...
... Products Ltd. announced today that walmart.com is ... is significant because sales velocities are being closely monitored ... retailers dedicate resources to educate and address dysphagia concerns ... crush or grind their meds/supplements and the Power Pill ...
Cached Medicine Technology:Endo Pharmaceuticals Successfully Completes Tender Offer for Shares of Penwest Pharmaceuticals 2Endo Pharmaceuticals Successfully Completes Tender Offer for Shares of Penwest Pharmaceuticals 3Endo Pharmaceuticals Successfully Completes Tender Offer for Shares of Penwest Pharmaceuticals 4VitaCarry(R) Handheld Power Pill Grinder Sales Capturing Retailer's Attention 2
(Date:7/9/2014)... 2014 For the first time, researchers have access ... in Canada uses health care. A new study, called ... demonstrate the unique challenges faced by urban Aboriginal people ... Hospital. , The findings, published today in ... Nations individuals and the general population. , Researchers interviewed ...
(Date:7/9/2014)... an innovative tool that captures heretofore hidden ways that ... a protein that makes breast cancer cells more likely ... trigger cancer,s spread in part by blocking two other ... that suggests these two disease processes could have unexpected ... July 10 issue of Nature , points to ...
(Date:7/9/2014)... drug users in Russia might contribute to HIV ... conducted by researchers from Boston University Schools of ... Petersburg Pavlov State University, sought to discover the ... of a cohort of HIV-positive people with lifetime ... arrested by police were more likely to share ...
(Date:7/9/2014)... (July 8, 2014) Researchers from Montefiore Medical ... Medicine of Yeshiva University will present new findings ... July 12 July 17 in Copenhagen, Denmark. Data ... could prompt transition from cognitive normality to mild cognitive ... Einstein Aging Study , established in 1980 to ...
(Date:7/9/2014)... one of the most important organs in the human ... our food properly this is its synthesis function ... organism this is its detoxification function. Lack of ... all damage the liver. The resulting diseased cells can ... life-threatening liver failure. According to the German Liver Foundation, ...
Breaking Medicine News(10 mins):Health News:Urban Aboriginal people face unique health challenges 2Health News:Protein pushes breast cancer cells to metastasize 2Health News:Protein pushes breast cancer cells to metastasize 3Health News:BU researchers relate arrests with HIV risk environment 2Health News:Investigators from Montefiore and Einstein to present data at 2014 Alzheimer's Association International Conference 2Health News:Investigators from Montefiore and Einstein to present data at 2014 Alzheimer's Association International Conference 3Health News:Telemedicine for patients with chronic liver diseases 2Health News:Telemedicine for patients with chronic liver diseases 3
... influenced by advertisements that show horrific consequences of drink-driving ... report . ,The UK Department of ... drink-driving can influence young men not to sit behind ... show that a minimum penalty of a one-year driving ...
... David Beckham has admitted that he is a big softie who ... recently moved to the US after joining LA Galaxy, said that ... while he is watching an upsetting scene in the film. ... we'll be watching a film that's not even upsetting and Victoria ...
... study has suggested that teens indulgence in non-suicidal ... suspected. ,Non-suicidal self-injury is the deliberate, ... intent. ,The findings are important because ... adolescents in the general population than previously thought, ...
... to gain approval from the Food and Drug Administration (FDA), ... Wilson Guthrie, a 61-year-old man from Kansas, suffering from ... home, with that experimental heart-assist device that keeps his heart ... the cardiothoracic ICU has had, and that a lot of ...
... last year in Sierra Leone's capital Freetown last year has ... ,A senior health worker attributed the fall in rabies cases ... Doctors at the main referral Connaught Hospital are worried about ... ,The hospital has had to rely heavily on ...
... who are not graduates of recognised foreign medical schools, ... to practise in Singapore starting next year, the ... from countries like the Philippines, India and Myanmar, have ... Medical Council has allowed institutions to hire them since ...
Cached Medicine News:Health News:Drink-drivers Not Influenced by Ads Unless It Affects Them Personally 2Health News:Self-harming Among Teens More Common Than Thought 2Health News:Self-harming Among Teens More Common Than Thought 3Health News:US Patient Implanted With HeartMate II, Leaves ICU 2
Peribulbar Needle, 25 g. Atkinson style bevel. Overall length 31 mm. 5/box....
Micro Blade tip 6900 style, straight. Dimensions: 15.2 mm x 2.5 mm x 6.2 mm....
Needle Knife, straight, full handle, non-reflective, 0.74 mm width....
Full Handle Laseredge Slit Blade Knife, 3.2 mm angled bevel up. Blade tip dimension: 14.4 mm x 3.2 mm x 3.7 mm....
Medicine Products: