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Kuros Announces Allowance of US Patent for the Local Application of Parathyroid Hormone (PTH) for Bone Healing

ZURICH, July 19, 2011 /PRNewswire/ --


Kuros Biosurgery AG, a biotechnology company focused on the development of novel biomaterials and bioactive-biomaterial combination products for trauma, wound and spinal indications, announced today that it has received Notice of Allowance for U.S. 11/679,807 from the U.S. Patent Office. The now allowed application acknowledges that Kuros has been first in showing that parathyroid hormone (PTH) when applied locally in a matrix to a bone defect has the ability to improve bone healing. Kuros has already demonstrated the clinical utility of this proprietary approach to bone healing in two large phase II studies in trauma patients which have reported previously.

Kuros is developing a portfolio of biomaterial, and bioactive-biomaterial combination, products. The Company's product candidates are based on two different matrix technology platforms.  Kuros' most advanced products are based on a fibrin matrix and include KUR-111 and KUR-113 which have achieved positive results in large Phase II trials for tibial plateau fractures and tibial shaft fractures respectively.

 Didier Cowling, Chief Executive Officer at Kuros says: "This patent will give Kuros broad protection on the concept of locally applied PTH to improve bone healing. Obtaining the notice of allowance for this US patent application further builds on Kuros' proprietary position in local treatments for bone generation and healing".

The Notice of Allowance for US 11/679,807 with its broad scope of protection follows US 7,247,609, US 6,331,422, US 6,607,740, EP 1 465 989, EP 1 124 590, EP 1 280 566 and patents in many other countries which protect Kuros` approach with PTH and its incorporation into matrices for local therapeutic applications.

About Kuros

Kuros is a biotechnology company that is focused on the development of novel biomaterials and bioactive-biomaterial combination products for trauma, wound and spinal indications.

Kuros has two biomaterial technology platforms, one based on fibrin sealants and the other based on its own proprietary synthetic technology that can mimic fibrin in many of its attributes.  These materials can be used alone or in combination with biologically active molecules.

Kuros' combination products are designed to mimic the body's natural healing process. The products consist of fusion proteins of naturally occurring bioactive factors, covalently incorporated into fibrin or synthetic matrices. The incorporation of the biologically active molecules into the injectable matrices aims to maximize their activity by retention at the site of action. Kuros products are designed to combine ease of application with localized delivery.  Kuros has a number of methodologies to achieve the desired retention and release profiles of the biologically active molecules.

Kuros' has a diverse pipeline of product candidates with its most advanced product candidates being in trauma and wound care.

Since its creation, Kuros has raised over $150 million. The company is located in Zurich, Switzerland.

Press Enquiries

Didier Cowling, CEO +41(0)44-200-56-62
Alistair Irvine, Director of Business Development +41(0)44-200-56-62

For Swiss Media Enquires:
IRF Communications
Martin Meier-Pfister +41(0)43-244-81-40
Jan Gregor +41(0)43-244-81-54

For International Media Enquires:
Citigate Dewe Rogerson
David Dible, Nina Enegren +44(0)207-638-9571

SOURCE Kuros Biosurgery AG
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