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Knowledge Based Reconstruction Demonstrates Accuracy in Obtaining Ventricular Volume and Function in Tetralogy of Fallot Patients, According to VentriPoint Diagnostics
Date:4/29/2008

Demonstration Signifies Completion of First Disease Database for the

VentriPoint Diagnostic System

SEATTLE, April 29 /PRNewswire/ -- VentriPoint Diagnostics today announced that Knowledge Based Reconstruction (KBR) enables accurate three dimensional reconstruction of right ventricular volume and function in patients with tetralogy of fallot (TOF) in significantly less time and for a lower cost than currently applied methods.

TOF is a disease that impacts the heart in multiple ways, such as creating a hole between the ventricles and developing levels of obstruction from the right ventricle to the lungs known as pulmonary stenosis. The three dimensional models also provided an understanding of changes to the shape of the right ventricle that doctors can use to analyze how the heart adapts to hemodynamic overload.

In a study of 20 patients with repaired TOF led by Florence H. Sheehan, M.D., of the University of Washington, the accuracy of the volume and ejection fraction of the right ventricle obtained with KBR was equal to or greater than the published accuracy of other methods of measurement. Using the VentriPoint Diagnostic System, KBR was applied as anatomical points identified on two dimensional images of the right ventricle of TOF diseased hearts were referenced with the KBR database comprised of 110 patients, including 54 with TOF. This is the first of four unique disease-specific KBR databases that VentriPoint is developing and plans to deploy when the VentriPoint Diagnostic System becomes commercially available.

"Applying Knowledge Based Reconstruction, our VentriPoint Diagnostic System completes critical ventricular measurements in significantly less time and lower cost than traditional methods to enable the cardiologists to better diagnose, monitor and track the efficacy of treatments," said Joseph Ashley, CEO of VentriPoint Diagnostics. "This validation of the tetralogy of fallot Knowledge Based Re
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SOURCE VentriPoint Diagnostics Ltd.
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