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Knee Pain? An Exclusive Study Engineers Cartilage to Match Patient's Own Tissue
Date:1/8/2008

MINNEAPOLIS, Jan. 8 /PRNewswire/ -- Patients with knee cartilage injuries now have the opportunity to re-grow their cartilage as part of an innovative study at TRIA Orthopaedic Center, in Bloomington, MN. Cartilage is the tough but flexible tissue that covers the ends of your bones at a joint such as the knee; symptoms of knee cartilage defects include pain, swelling and catching. In the United States alone, knee pain ranks the second highest source of musculoskeletal-related physician visits in 2005, according to the National Ambulatory Medical Care Survey. This new implant technology, NeoCart(R), regenerates this injury-prone tissue within a bio-engineered material, grown from the patient's own cartilage cells. The matrix matches his or her unique cartilage characteristics, and is being studied as an alternative to a standard therapy called microfracture. Dr. Brad Nelson, Orthopaedic Surgeon and Principal Investigator for TRIA, will be implanting this engineered tissue matrix for a select number of patients.

Histogenics Corporation, makers of NeoCart(R), successfully completed Phase I of the NeoCart(R) clinical trial, demonstrating the safety of the technique in a small number of patients, and is now in Phase II, where NeoCart(R) will be compared with a standard therapy called microfracture. TRIA Orthopaedic Center is one of a limited number of sites in the country, and the only site in Minnesota, chosen to participate in the study. "We are thrilled to be one of five centers nationally participating in this clinical trial," said Ryan Graver, Director of Research and education for TRIA. "This kind of cutting-edge research improves Orthopaedic treatments and outcomes that our patients can expect. Our commitment is to improve care for all Orthopaedic patients and it is through such projects TRIA is beginning to translate science into advancements in clinical care."

Since the body does not naturally re-grow cartilage without medical intervention t
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SOURCE TRIA Orthopaedic Center
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