Navigation Links
Knee Pain? An Exclusive Study Engineers Cartilage to Match Patient's Own Tissue
Date:1/8/2008

MINNEAPOLIS, Jan. 8 /PRNewswire/ -- Patients with knee cartilage injuries now have the opportunity to re-grow their cartilage as part of an innovative study at TRIA Orthopaedic Center, in Bloomington, MN. Cartilage is the tough but flexible tissue that covers the ends of your bones at a joint such as the knee; symptoms of knee cartilage defects include pain, swelling and catching. In the United States alone, knee pain ranks the second highest source of musculoskeletal-related physician visits in 2005, according to the National Ambulatory Medical Care Survey. This new implant technology, NeoCart(R), regenerates this injury-prone tissue within a bio-engineered material, grown from the patient's own cartilage cells. The matrix matches his or her unique cartilage characteristics, and is being studied as an alternative to a standard therapy called microfracture. Dr. Brad Nelson, Orthopaedic Surgeon and Principal Investigator for TRIA, will be implanting this engineered tissue matrix for a select number of patients.

Histogenics Corporation, makers of NeoCart(R), successfully completed Phase I of the NeoCart(R) clinical trial, demonstrating the safety of the technique in a small number of patients, and is now in Phase II, where NeoCart(R) will be compared with a standard therapy called microfracture. TRIA Orthopaedic Center is one of a limited number of sites in the country, and the only site in Minnesota, chosen to participate in the study. "We are thrilled to be one of five centers nationally participating in this clinical trial," said Ryan Graver, Director of Research and education for TRIA. "This kind of cutting-edge research improves Orthopaedic treatments and outcomes that our patients can expect. Our commitment is to improve care for all Orthopaedic patients and it is through such projects TRIA is beginning to translate science into advancements in clinical care."

Since the body does not naturally re-grow cartilage without medical intervention the knee joints are prone to degeneration and osteoarthritis. The NeoCart(R) implant, to replace the damaged cartilage, is cultured from an initial biopsy where a pea size amount of a patient's healthy cartilage is extracted. The biopsy sample is processed to pinpoint the cartilage producing cells, then injected into a 3-D bioengineered matrix and placed under high pressure to grow the cartilage. This matrix, with the same characteristics of the patient's own cartilage, is then implanted to replace the damaged cartilage. Patients participating in this study will receive either NeoCart(R) or standard microfracture therapy.

TRIA has the potential to offer this research opportunity to 10 -15 patients. Patients between the ages of 18-55 with knee pain symptoms indicative of an articular cartilage injury may be eligible to enroll in the study. Patients in the study will have a MRI study and must be able to undergo arthroscopic microfracture or biopsy and subsequent surgery for NeoCart implantation.

There is no charge to the patient for the NeoCart implant used in this study. The treatment cost of the patient's knee cartilage injury will remain the same regardless of participation in the study, and is normally covered under your medical/hospital insurance plan. Individuals interested in participating in this study, or physicians wanting more information, should contact Dan Schwartz, TRIA Orthopaedic Center, at 952-831-8742.

TRIA Orthopaedic Center is a state-of-the-science partnership of Park Nicollet Health Services, University of Minnesota Physicians and The Orthopaedic Center. This revolutionary facility delivers orthopaedic treatment, surgery, rehabilitation, therapy, pharmacy, research and physician education -- all under one roof. TRIA specialists train over 600 national and international surgeons on the latest techniques in orthopaedic surgery in our Bio-Skills Laboratory. TRIA is conveniently located at France Avenue and I- 494. To contact TRIA Orthopaedic Center, call 952-831-8742 or visit our website at http://www.tria.com.


'/>"/>
SOURCE TRIA Orthopaedic Center
Copyright©2008 PR Newswire.
All rights reserved

Related medicine technology :

1. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
2. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
3. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
4. Allos Therapeutics Initiates Study of PDX in Patients with Cutaneous T-Cell Lymphoma
5. Multiple Myeloma Research Consortium (MMRC) Partners with Novartis to Advance Phase II Study of Deacetylase Inhibitor
6. Potential Safety Issue Identified in Ongoing Phase 2 Clinical Study of HCV-796
7. Study Suggests High-Dose Fish Oil May Significantly Improve Behavior in Children with ADHD
8. MicroDose Announces Positive Results From the QDose Inhaled Insulin Glucose Clamp Study
9. Video: Landmark Study in The Lancet: Patients Treated With Betaseron(R) After First MS Attack Experienced Significant Delay in MS Progression
10. MacroGenics Begins Global Phase 2/3 Protege Study in Recent-onset Type 1 Diabetes Mellitus
11. Sarasotas Roskamp Institute Releases Study Defining a Mechanism for Development of Obesity and the Metabolic Syndrome, Forerunners of Type 2 Diabetes
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/20/2017)... , April 20, 2017  Zimmer Biomet Holdings, Inc. ... healthcare, today announced that it will be participating in ... at the InterContinental Hotel in Boston, Massachusetts ... will present at 11:20 a.m. Eastern Time. ... via Zimmer Biomet,s Investor Relations website at http://investor.zimmerbiomet.com ...
(Date:4/20/2017)... WOONSOCKET, R.I. , April 20, 2017 /PRNewswire/ ... (NYSE: CVS), today unveiled a new store design ... new assortment of healthier food, health-focused products and ... the store to help customers discover new offerings. ... represent the next evolution of the customer experience ...
(Date:4/20/2017)... Eyevensys, a private biotechnology company developing its ... that enables the safe, local, sustained production of therapeutic ... of ophthalmic diseases, announces it has received approval from ... to advance its technology into clinical development. ... The EyeCET platform uses ...
Breaking Medicine Technology:
(Date:4/25/2017)... ... 2017 , ... ProRehab Physical Therapy (PRPT) is ... therapy provider for Derby City CrossFit, effective immediately. , In addition to treating ... effectively as possible, ProRehab’s sports physical therapists will work with athletes to maximize ...
(Date:4/25/2017)... BC (PRWEB) , ... April 25, 2017 , ... The ... from Richmond, BC, who live with dental fear and require sedation to receive dental ... at ease during various procedures, from hygienic cleanings to oral surgery, at their ...
(Date:4/25/2017)... ... April 25, 2017 , ... Back Pain Centers ... back pain with a reputable physician in their area, announces the launch of a ... information for patients who are looking for reputable physicians to help them with back ...
(Date:4/25/2017)... ... 25, 2017 , ... There is no better place in South Florida to ... in the May issue of Consumer Reports focused on heart health. , The ... during and after coronary bypass and aortic valve replacement procedures. , Consumer Reports ...
(Date:4/24/2017)... ... 24, 2017 , ... Michael Vick announced his retirement earlier this year from ... overall number one pick in the 2001 NFL Draft, to the Atlanta Falcons, made ... the most career rushing yards by a quarterback (6,109) and the most rushing yards ...
Breaking Medicine News(10 mins):