Navigation Links
King Pharmaceuticals Showcases Data From Pain Pipeline of Medicines Designed to Deter Common Methods of Non-Therapeutic Use
Date:6/25/2009

erse event profile was similar to that seen with short-acting oxycodone, and ACUROX(R) was generally well tolerated.

Evaluation of Plasma Naltrexone Concentrations Resulting From Use of ALO-01 (morphine sulfate extended-release with sequestered naltrexone hydrochloride) Capsules for Chronic Pain

EMBEDA(TM) Capsules (ALO-01), a novel opioid formulation, contain pellets of an extended-release formulation of morphine sulfate surrounding an inner core of naltrexone hydrochloride. EMBEDA(TM) is intended to treat moderate to severe chronic pain. This 12 month open-label safety study evaluated the plasma concentrations of naltrexone following use of ALO-01 (morphine sulfate and naltrexone hydrochloride). Samples were drawn to measure plasma concentrations (concs) of morphine (M) naltrexone (N) and its metabolite, 6-beta-naltrexol (6-beta-N) when taken as directed. Results showed that, when ALO-01 was taken as directed, steady state plasma morphine levels remain stable. Naltrexone and 6-beta-N do not accumulate; small amounts, when detected, were not dose related and not associated with clinically observable effects of opioid withdrawal or reduction of pain relief.

Phase II Study to Evaluate the Dose Response for Flushing, Safety and Tolerability of Escalating Doses of Niacin in Fasted and Fed Healthy Adult Volunteers

ACUROX(R) Tablets, with Aversion(R) Technology, are a composition of oxycodone HCl, niacin, and other inactive ingredients. The niacin ingredient can generate a temporary, but increasingly unpleasant effect, including flushing. A Phase II study was conducted to evaluate the dose response for niacin-induced flushing, the effect of food on niacin-induced flushing, and the safety and tolerability of varying doses of niacin. Volunteers were broken into two groups (fed and fasted) and were provided varying doses of niacin to consume over a period of
'/>"/>

SOURCE King Pharmaceuticals, Inc.
Copyright©2009 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Auxilium Pharmaceuticals, Inc. Receives Clearance to Resume Clinical Trials for XIAFLEX(TM)
2. Vion Pharmaceuticals Completes Accrual of 85 Patients to its Pivotal Phase II Trial of Cloretazine(R) (VNP40101M) in Elderly AML
3. Solvay Pharmaceuticals, Inc. and Wyeth Pharmaceuticals Announce Receipt of an FDA Action Letter for Bifeprunox, an Investigational Treatment for Schizophrenia
4. Callisto Pharmaceuticals Opens Additional Sites for Phase II Clinical Trial of Atiprimod in Advanced Carcinoid Cancer Patients
5. WallSt.net (www.wallst.net) Updates the Investment Community Through an All-New Interview With RegeneRx Biopharmaceuticals CEO
6. Quark Pharmaceuticals, Inc. Presented Positive Preclinical Results of Systemic RNAi Compound for Acute Renal Failure (ARF)
7. Peregrine Pharmaceuticals Doses First Patient in Cotara(R) Phase II Brain Cancer Trial In India
8. Nabi Biopharmaceuticals Announces Second Quarter 2007 Financial Results
9. Access Pharmaceuticals Provides Update on Clinical Development Plan of ProLindac
10. Quark Pharmaceuticals Extends Research Agreement with State University of New York for Proprietary siRNA Compounds for Acute Hearing Loss
11. Acura Pharmaceuticals, Inc. Secures Financing to Fund Pivotal Phase III Clinical Trial for Lead Aversion(R) Technology Product Candidate
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:9/19/2014)... WHITEHOUSE STATION, N.J. , Sept. 19, 2014 Merck ... the United States and Canada , ... on Desafiando La Diabetes: Logra Tus Metas , an educational ... of their blood sugar -- a key treatment goal to help ... the United States are at a higher risk for ...
(Date:9/19/2014)... Sept. 19, 2014 Larry J. Merlo , ... ), will speak before the National Press Club in ... company,s recent move to stop selling tobacco products and its ... of health. "Dramatic changes in our health care ... and government," Merlo has said. "CVS Health has a truly ...
(Date:9/19/2014)... , Sept. 19, 2014  BioSpecifics Technologies Corp. (NASDAQ: ... class collagenase-based products marketed as XIAFLEX ® in the ... that BioSpecifics, President, Tom Wegman , will present a ... in the Biotech Industry Conference. The presentation ... p.m. EDT at the Millennium Broadway Hotel in ...
Breaking Medicine Technology:Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 2Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 3Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 4Celebrity Chef Leticia Moreinos Schwartz Partners with Merck on Desafiando La Diabetes: Logra Tus Metas to Urge Hispanics With Type 2 Diabetes to Get to Their A1C Goal 5CVS Health CEO to Address National Press Club on Landmark Decision to Quit Tobacco, Leadership in Health Care Innovation 2CVS Health CEO to Address National Press Club on Landmark Decision to Quit Tobacco, Leadership in Health Care Innovation 3BioSpecifics Technologies Corp. to Present at the 21st Annual BioCentury NewsMakers in the Biotech Industry Conference 2
(Date:9/20/2014)... PA (PRWEB) September 20, 2014 "As a ... in their tanks," said an inventor from Tamaqua, Pa. "The ... mounted on the backs of their chairs. My invention enables ... developed the Kam Oxygen Sensor to make it easier to ... that the user knows when the tank is low. It ...
(Date:9/20/2014)... Earlier this week, Home Depot revealed that up ... credit card information pilfered by hackers, surpassing the 40 million ... articles like this one published by Bloomberg on ... , “Most people tend to focus on how many ... to score a game,” says Joe Caruso, founder and CEO/CTO ...
(Date:9/20/2014)... September 20, 2014 Final Cut Pro ... the release of the Information theme for FCPX filmmakers. , ... to describe the Information theme,” says Christina Austin, CEO of ... look so professional.” , Information features easy to use controls ... of the environment. Change the background color, color of each ...
(Date:9/20/2014)... “Motherhood is a wonderful gift and a huge responsibility,” ... article , “We know that you want to care for ... want to do as well.” , The article explains to ... their Family Physicians who practice obstetrics while pregnant, during delivery, ... To learn more about Community Health Center of Snohomish County ...
(Date:9/19/2014)... 20, 2014 Nearly 780 Risperdal lawsuits ... Pleas where a meeting took place to discuss the ... in the court’s mass tort program. Attorneys for ... past week at the Complex Litigation Center in Philadelphia’s ... pretrial proceedings. The Risperdal lawsuits filed against Johnson & ...
Breaking Medicine News(10 mins):Health News:Don’t Let Data Breach Fatigue Cause Dangerous Cyber Security Complacency 2Health News:Don’t Let Data Breach Fatigue Cause Dangerous Cyber Security Complacency 3Health News:Don’t Let Data Breach Fatigue Cause Dangerous Cyber Security Complacency 4Health News:Don’t Let Data Breach Fatigue Cause Dangerous Cyber Security Complacency 5Health News:Today Pixel Film Studios Announced the Release of the Information Theme for Final Cut Pro X 2Health News:Newest Article from Community Health Center of Snohomish County Highlights The Importance of Proper Health Care for Expectant Mothers 2Health News:Risperdal Lawsuits Move Forward As Attorneys Meet To Discuss Litigation, Reports Wright & Schulte LLC 2Health News:Risperdal Lawsuits Move Forward As Attorneys Meet To Discuss Litigation, Reports Wright & Schulte LLC 3Health News:Risperdal Lawsuits Move Forward As Attorneys Meet To Discuss Litigation, Reports Wright & Schulte LLC 4
... claim up to 3 million lives a year. WHO released ... of March. The report says most of those who die ... in the developing world are particularly at risk for water-borne ... drinking contaminated water and 90% of those deaths are among ...
... always raises many uncomfortable questions and more troubling answers is ... ethical issue and has kindled a lot of heated arguments ... victims suffer the most when it comes to drug testing ... on unsuspecting victims in the name of conducting a study.,A ...
... toddler, aged 13 months from Edmonton, Alberta, wandered into a ... in sub zero temperatures. She was frozen stiff and her ... the hospital, doctors declared her clinically dead, but lo and ... miraculous recovery. Read on to know more. , The temperature ...
... conducted by Dr. Michael Brent, an associate professor of ... gives us an insight into the way children understand ... were presented at the annual meeting of the American ... years the ability of children to pick up language ...
... ad with a macabre sense of humour. It stirred up ... over the United States. Levis Strauss officially announced that the ... complaints from many who felt that they did not enjoy ... shows an unconscious man falling from a carousel horse. A ...
... doctors are being stretched to their limits working on cases ... in candlelight when the power fails, but the work goes ... open verandahs. On Jan 27th nearly 1500 patients were operated ... rays. ,The worst quake in Indian history has ...
Cached Medicine News:
... is synthesized in the parafollicular C-cells of ... secretory granules. The major action of calcitonin ... inhibiting osteoclast activity, resulting in decreased mobilization ... is most evident in conditions associated with ...
... test provides a method for the lay user ... is comprised of a plastic probe with pH ... a package insert. The plastic probe is in ... is indicated for measuring vaginal pH for the ...
... The Rapidlab 1200's speed and accuracy ... decisions in a timely manner - ... value, especially patients. In fact, the ... parameters in just one minute. Its ...
Dornier Holmium Laser for Urological Procedures...
Medicine Products: