Navigation Links
KineMed Presents Preclinical Data for Investigational Agent Demonstrating Neurogenesis and Confirming Improvements in Behavioral Model
Date:10/11/2007

EMERYVILLE, Calif., Oct. 11 /PRNewswire/ -- KineMed Inc., a pathway-based drug discovery and development company, announced today presentation of data demonstrating the ability of an investigational agent to regenerate nerve cells in the hippocampus, a part of the brain involved with cognition and mood. The agent, part of a partnered relationship in indications discovery, also improved performance in a behavioral test in a preclinical model. The findings were disclosed in a presentation titled, "Indications Discovery Using In Vivo Pathways as Targets," at the second annual Drug Repositioning Summit hosted by Cambridge Healthtech Institute in Philadelphia.

According to presenter Scott Turner, Ph.D., Vice President, Research at KineMed, "The KineMed team set out to demonstrate regenerative capacity in the hippocampus because all known anti-depressants stimulate hippocampal neurogenesis, and an increase in hippocampal neurogenesis correlates with improved learning and memory. Based on the reported findings, we believe we have identified a compound that could indeed have application in treating cognitive impairment, an area of substantial unmet clinical need."

David Fineman, President and CEO of KineMed, stated, "The current findings demonstrate the power of KineMed's technology, which measures the flow of molecules through intact metabolic pathways. Using this technology, KineMed is able to take a shelved compound, or an entire drug class, and put it back into the clinic, thereby derisking the class of compounds. This is unique from other efforts because our testing takes place in the intact human and animal. As described in the research presentation, we are able to demonstrate a compound's ability to increase hippocampal neurogenesis, providing a rationale for the compound's behavioral outcome."

Mr. Fineman added, "We are proud of the achievements of our team and look forward to further progress in these and other efforts."

Dr. Turner al
'/>"/>

SOURCE KineMed Inc.
Copyright©2007 PR Newswire.
All rights reserved

0

GOOD

Page: 1 2 3

Related medicine technology :

1. KineMed Presents Data Measuring Changes in Reverse Cholesterol Transport for the First Time
2. Inspiration Biopharmaceuticals Presents Data From Hemophilia Program at International Society On Thrombosis and Haemostasis (ISTH) Annual Meeting
3. European Society for Medical Oncology (ESMO) Presents Data from the Clinical Trial of MediGenes Cancer-Killing Virus in Press Conference
4. Cytogen Presents Phase 1 Data Showing Promising Antitumor Activity and Safety Profile of Quadramet at International Myeloma Workshop
5. SemBioSys Presents Positive Insulin Data at the American Diabetes Association Conference
6. Tranzyme Pharma Presents Initial Phase IIa Data for its Novel Ghrelin Agonist, TZP-101, in Patients with Diabetic Gastroparesis
7. Novagali Pharma Presents at AACO the Results of its Pivotal Phase III Clinical Trial of Vekacia in Children Suffering From Vernal Keratoconjunctivitis
8. BioLife Solutions Presents Data on CryoStor at International Society for Cellular Therapy Annual Meeting
9. Genaera Presents Preclinical Data on Trodusquemine (MSI-1436) for the Treatment of Obesity at the American Diabetes Association 67th Scientific Session
10. Elixir Pharmaceuticals Presents Preclinical Data Highlighting Its Ghrelin Antagonist Program at the American Diabetes Associations Annual Meeting
11. DiObex Presents Phase 2a Data of DIO-902 Demonstrating Trends of Improved Glycemic Control and Significant Reductions of LDL-Cholesterol and C-Reactive Protein
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/4/2009)BILLERICA, Mass., Dec. 4 Axsun Technologies, Inc., a wholly-owned subsidiary of Volcano Corporation (Nasdaq: VOLC ), today announced the initial development and successful testing of a novel integra
(Date:12/4/2009)TARRYTOWN, N.Y., Dec. 4 Bayer Diabetes Care today announced the three grand prize winners of Bayer,s "Express Your Simple Win Creativity Contest." Nick Jonas, of the Jonas Brothers, selected the winn
(Date:12/4/2009)WILMINGTON, Del., Dec. 4 AstraZeneca (NYSE: AZN ) today announced that the US Food and Drug Administration (FDA) has approved once-daily SEROQUEL XR® (quetiapine fumarate) Extended Release Tab
Breaking Medicine Technology:Axsun Technologies, A Wholly-Owned Subsidiary of Volcano Corporation, Announces Breakthrough Integrated Light Source Architecture for Optical Coherence Tomography (OCT) Imaging 2Axsun Technologies, A Wholly-Owned Subsidiary of Volcano Corporation, Announces Breakthrough Integrated Light Source Architecture for Optical Coherence Tomography (OCT) Imaging 3Axsun Technologies, A Wholly-Owned Subsidiary of Volcano Corporation, Announces Breakthrough Integrated Light Source Architecture for Optical Coherence Tomography (OCT) Imaging 4Axsun Technologies, A Wholly-Owned Subsidiary of Volcano Corporation, Announces Breakthrough Integrated Light Source Architecture for Optical Coherence Tomography (OCT) Imaging 5Bayer 'Express Your Simple Win Creativity Contest' Grand Prize Winners Announced 2Bayer 'Express Your Simple Win Creativity Contest' Grand Prize Winners Announced 3US FDA Approves SEROQUEL XR(R) For Add-On Treatment of Major Depressive Disorder 2US FDA Approves SEROQUEL XR(R) For Add-On Treatment of Major Depressive Disorder 3US FDA Approves SEROQUEL XR(R) For Add-On Treatment of Major Depressive Disorder 4US FDA Approves SEROQUEL XR(R) For Add-On Treatment of Major Depressive Disorder 5US FDA Approves SEROQUEL XR(R) For Add-On Treatment of Major Depressive Disorder 6US FDA Approves SEROQUEL XR(R) For Add-On Treatment of Major Depressive Disorder 7US FDA Approves SEROQUEL XR(R) For Add-On Treatment of Major Depressive Disorder 8US FDA Approves SEROQUEL XR(R) For Add-On Treatment of Major Depressive Disorder 9New Fertility Financing Program for Donated Eggs Fills Void Left by Capital One 59486 1New Fertility Financing Program for Donated Eggs Fills Void Left by Capital One 59486 2PEAK Surgical Announces Results of First PRECISE Studies at American College of Surgeons Clinical Congress 5492 1PEAK Surgical Announces Results of First PRECISE Studies at American College of Surgeons Clinical Congress 5492 2PEAK Surgical Announces Results of First PRECISE Studies at American College of Surgeons Clinical Congress 5492 3At Waters Forum Rep DeLauro Administration Urge Congress to Improve the Safety of Imported Food 59483 1At Waters Forum Rep DeLauro Administration Urge Congress to Improve the Safety of Imported Food 59483 2At Waters Forum Rep DeLauro Administration Urge Congress to Improve the Safety of Imported Food 59483 3
(Date:12/5/2009)Wind Turbines are popping up in the most unusual places, and to do everything from growing mushrooms, making wine to keeping prisoners in jail! , (PRWEB) December 5, 2009 -- W
(Date:12/4/2009)NEW YORK, Dec. 4 Care Investment Trust Inc. (NYSE: CRE ) ("Care" or the "Company") today announced that its Board of Directors has declared a dividend of $0.17 per share of common stock. The div
(Date:12/4/2009)SAN FRANCISCO, Dec. 4 Medithrive, Inc. has won the Patient,s Choice Award as the favorite dispensary in the SF Bay Area by popular vote conducted by the online website, www.weedmaps.com. Despite on
(Date:12/4/2009)WASHINGTON, Dec. 4 The American Association of Homes and Services for the Aging (AAHSA) applauds the Senate for ensuring that the Community Living and Supportive Services (CLASS) provisions remain i
(Date:12/4/2009)KANSAS CITY, Mo., Dec. 4 The large, two-day free health clinic sponsored by the National Association of Free Clinics (NAFC) in Kansas City on Wednesday and Thursday is not just for the sick but also
Breaking Medicine News(10 mins):Health News:Distributor Announces New Applications for Wind Turbines 2Health News:Distributor Announces New Applications for Wind Turbines 3Health News:Care Investment Trust Inc. Declares Quarterly Dividend of $0.17 Per Share 2Health News:Free Health Clinic Event Is Not Just for the Sick 2
...reveals a new immune defense mechanism in normal a...ic fibrosis (CF) are particularly susceptible to b...int the way to new approaches for treating the dis...d that this process is defective in airway tissue ...
...ight training program produce more biologically ac...ogists //to understand why weight training improve... A study published in the December issue of the...eight training regimens. The research found that t...
...cal health agencies with the most effective ways o...r personal communication and proper condom use, fo...excluded from consideration needle-exchange and su... Disease Control and Prevention examined 100 HIV p...
...young women who grow up in cities or move there fr...mia.// Princess Diana was known to suffer from...grew up in the country, and moved to London as a t...erved a startling correlation between cases of thi...
...cted three men one of them has developed a flesh e...soning and renal failure.// Necrotising fasc... ultimately leads to death. The person with ...attooist has to improve the standards of infection...
...vered a protein interaction that may explain how t.../ The findings, published in and featured on the c...ics, show how the mutated Huntington’s protein int...network among brain cells and in maintaining their...
Other Medicine News:Health News:Newly Discovered Immune Defense May Be Impaired In CF Airways 2Health News:Varying Weight Training Intensity Ups Growth Hormone in Women 2Health News:Best HIV-Prevention Programs Help People Build Skills 2Health News:Best HIV-Prevention Programs Help People Build Skills 3Health News:Link Between Huntington’s and Abnormal Cholesterol Levels in Brain Establishe 2
... Laboratories is a national reference laboratory a...earch and development. ARUP offers an extensive te... in clinical and anatomic pathology. Owned by the ...lude more than half of the nation's university tea...
... Laboratories is a national reference laboratory a...earch and development. ARUP offers an extensive te... in clinical and anatomic pathology. Owned by the ...lude more than half of the nation's university tea...
... Laboratories is a national reference laboratory a...earch and development. ARUP offers an extensive te... in clinical and anatomic pathology. Owned by the ...lude more than half of the nation's university tea...
... Laboratories is a national reference laboratory a...earch and development. ARUP offers an extensive te... in clinical and anatomic pathology. Owned by the ...lude more than half of the nation's university tea...
Medicine Products: