Navigation Links
Key patent awarded to Adjuvance co-founders for pioneering method of producing rare vaccine component.

NEW YORK, Nov. 14, 2012 /PRNewswire-iReach/ -- Adjuvance Technologies, Inc. announced that the United States Patent and Trademark Office has granted Adjuvance co-founders a patent for a pioneering invention which provides a novel synthetic method to produce saponin adjuvants including QS-21, a leading vaccine adjuvant currently used in advanced clinical trials for infectious disease, neurodegenerative disorders and oncology. Despite adjuvants' critical ability to improve the immune response to vaccine antigens, there are very few adjuvants approved for human use in the U.S.

"Before this innovative approach to producing saponin adjuvants, tedious isolation and purification protocols were necessary to obtain these materials. This work will greatly facilitate access to these promising molecules for investigators and vaccine developers" said Jeffrey Gardner, Adjuvance Technologies' CEO and co-founder. As exclusive licensee of the technology, Adjuvance will continue to focus on the commercial development of saponin adjuvants for use in innovative therapeutic and prophylactic human vaccines as well as pandemic preparedness and biodefense efforts.

"At Adjuvance, we believe this technology, which was developed at the Sloan-Kettering Institute of Memorial Sloan-Kettering Cancer Center, represents a fundamental breakthrough in vaccine adjuvant design and manufacturing. This patented technology will be able to expand and accelerate global vaccine programs that require a more secure, consistent source of these promising vaccine adjuvants," noted Mr. Gardner. U.S. Patent No. 8,283,456 was awarded to Drs. David Gin, Philip Livingston, Govind Ragupathi and others for "Triterpene saponins, methods of synthesis, and uses thereof."

About QS-21

QS-21 is a lead investigational adjuvant that has exhibited superior efficacy for a range of vaccine antigens. QS-21 has been widely used in over 100 clinical trials involving approximately 16,000 people. QS-21's ability to augment clinically significant responses to vaccine antigens has convinced GlaxoSmithKline, Johnson & Johnson, CSL and Merck to incorporate QS-21 into their drug development pipelines. In its naturally derived form, QS-21 is a semi-purified plant extract isolated by the harvesting of a rare South American tree, which translates to unique production challenges for vaccine makers. Adjuvance's new patented technology overcomes these production challenges by providing an ecologically sustainable synthetic product that is extremely pure, dependable and scalable.

About Adjuvance Technologies, Inc.

Adjuvance Technologies is a privately owned biopharmaceutical company based in New York. Adjuvance holds an exclusive license to the technology that enables the synthesis of QS-21 as well as an exclusive license to novel analogs with improved tolerability, efficacy and stability. Adjuvance has overcome natural QS-21's production challenges. Adjuvance's patented technology makes it possible to manufacture with consistently high purity and dependability synthetic QS-21 (SAPONEX) as well as an array of novel proprietary TITERQUIL saponin adjuvants on a large scale. More information is available at

Media Contact: Jeffrey Gardner Adjuvance Technologies, 3475594258,

News distributed by PR Newswire iReach:


SOURCE Adjuvance Technologies, Inc.
Copyright©2012 PR Newswire.
All rights reserved

Related medicine technology :

1. Essential Medical Dismisses Patent Case against Masimo and Cercacor
2. Ampio Awarded US and Canadian Patents that will Bolster the Commercialization of Optina™ for the treatment of Diabetic Macular Edema (DME)
3. Inovio Pharmaceuticals Granted U.S. Patent Protection for Synthetic Vaccine for Cervical Dysplasia and Cancer
4. U.S. Patent Office Issues Sixth Patent Covering Zero-Footprint Medical Image Viewers to Heart Imaging Technologies, LLC
5. Biodels Intellectual Property Position Strengthened for Ultra-Rapid-Acting Insulin Programs by Notice of Intent to Grant from European Patent Office
6. DURECT Announces Issuance of U.S. Patents Covering ORADUR® Technology
7. Broad Patent Protection Granted for iBio Immunomodulator
8. Bio-AMD, Inc.; Patent Application for Cartridge Test Cap
9. Coloplast Wins Patent Infringement Verdict Against Generic Medical Devices, Inc.
10. ICU Medical, Inc. Plans to "Vigorously Seek to Collect Damages" in wake of Patent Infringement Victory Over RyMed Technologies
11. NeuroSigma Subsidiary Acquires Thin-Film Nitinol Fabrication Patent Portfolio
Post Your Comments:
(Date:11/26/2015)... , Nov. 26, 2015 Research and ... the "Advanced Wound Care Market by Type (Dressings, ... End User (In-Patient Facility, Out-Patient Facility), and Geography - ... --> --> ... description, definition and forecast of the global advanced wound ...
(Date:11/26/2015)... ) has announced ... High Viscosity Drugs" report to their offering. ... addition of the "Self Administration of High ... --> Research and Markets ( ) ... Administration of High Viscosity Drugs" report to ...
(Date:11/26/2015)... , November 26, 2015 /PRNewswire/ ... announced the addition of the  "2016 ... the European Cell Surface Marker Testing ... Opportunities"  report to their offering.  ... the addition of the  "2016 Future ...
Breaking Medicine Technology:
(Date:11/27/2015)... VVA (PRWEB) , ... November 27, 2015 , ... ... motto of progress through sharing, the 2016 Building Better Radiology Marketing ... The conference will begin on Sunday, March 6, 2016, at Caesars Palace in ...
(Date:11/27/2015)... ... November 27, 2015 , ... CBD College is proud to ... Programs (CAAHEP) awarded accreditation to its Diagnostic Medical Sonography program. CBD College is honored ... one of twelve colleges and universities in the state of California make the cut. ...
(Date:11/26/2015)... ... November 26, 2015 , ... Patients at Serenity Point ... come together on Thanksgiving Day to share the things that they are most ... Serenity Point YouTube channel, patients displayed what they wrote on index cards, describing ...
(Date:11/26/2015)... ... , ... Jobs in hospital medical laboratories and in the imaging field lead ... Aureus Medical Group . These fields, as well as travel nursing, ... healthcare jobs through the company’s website, , The leading healthcare staffing ...
(Date:11/26/2015)... ... November 26, 2015 , ... Indosoft Inc., developer and distributor of the ... to improve system efficiency and reliability. , The new Q-Suite 6 platform is based ... system avoids locking itself into a specific piece of software for many key components ...
Breaking Medicine News(10 mins):