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Keryx Biopharmaceuticals Announces Highlights from Zerenex™ (ferric citrate) Poster Presentations at American Society of Nephrology Kidney Week 2011 Annual Meeting
Date:11/14/2011

ron prescribing behavior in response to spontaneous, non-treatment related increases in transferrin saturation (TSAT) and serum ferritin similar to those measured in previous clinical trials of Zerenex.  Data were analyzed from patients experiencing rises in TSAT (greater than or equal to 10%) and serum ferritin (greater than or equal to 15% and less than or equal to 25%).

The researchers concluded that physicians may respond to rises in TSAT and serum ferritin by reducing ESA and iron doses, particularly in patients with high baseline use, and, if approved, Zerenex may reduce ESA and iron usage by hemodialysis patients and have incremental economic value within the Medicare bundle reimbursement plan.

Ron Bentsur, Chief Executive Officer of Keryx Biopharmaceuticals, commented, "It's encouraging to see from a large database of dialysis patients that increases in TSAT and ferritin parameters, similar to those observed in clinical trials of Zerenex, could result in lower ESA and IV iron use, potentially generating significant cost savings for dialysis clinics." Mr. Bentsur, continued, "We'd like to thank DaVita Clinical Research for conducting these important analyses."  

The Zerenex Phase 3 registration program, which is being conducted pursuant to a SPA agreement with the FDA, is comprised of an already successfully completed Phase 3 short-term study, and an ongoing Phase 3 long-term study.

Keryx holds a worldwide license (except for certain Asian Pacific countries) to Zerenex (ferric citrate) from Panion & BF Biotech, Inc. The Japanese rights are sublicensed by Keryx to Japan Tobacco Inc. and Torii Pharmaceutical Co., Ltd.

ABOUT KERYX BIOPHARMACEUTICALS, INC.
Keryx Biopharmaceuticals is focused on the acquisition, development and commercialization of medically important pharmaceutical products for the treatment of cancer and renal disease. Keryx is developing KRX-0401 (perifosine), a novel, potentially
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SOURCE Keryx Biopharmaceuticals, Inc.
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