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Keryx Biopharmaceuticals Announces Highlights from Zerenex™ (ferric citrate) Poster Presentations at American Society of Nephrology Kidney Week 2011 Annual Meeting
Date:11/14/2011

NEW YORK, Nov. 14, 2011 /PRNewswire/ -- Keryx Biopharmaceuticals, Inc. (Nasdaq: KERX) today announced that two posters highlighting potential cost savings based on observations from previous clinical trials of Zerenex™ (ferric citrate) were presented by DaVita Clinical Research this past weekend during the American Society of Nephrology (ASN) Kidney Week 2011 Annual Meeting and Exposition in Philadelphia.  Zerenex, an oral, ferric iron-based drug candidate, is currently in Phase 3 clinical development for the treatment of hyperphosphatemia in end-stage renal disease patients on dialysis pursuant to a Special Protocol Assessment (SPA) agreement with the FDA.  

Key highlights from the two poster presentations are as follows:

Poster #1566: TSAT and Serum Ferritin Increases Observed in Ferric Citrate Clinical Trials May Lead to Dialysis Cost Savings
DaVita Clinical Research developed a cost model quantifying potential savings associated with reduced erythropoietin stimulating agent (ESA) and intravenous (IV) iron dosing observed in a large database of hemodialysis patients experiencing similar increases in iron storage markers as observed in previous clinical trials of Zerenex.  

The results of the cost model, using publicly available industry cost data, indicate that Zerenex, a ferric iron containing phosphate binder, could produce monthly cost savings of $125/patient for moderate ESA users (4,500 to <9,000 units per session) and $320/patient for high ESA users (greater than or equal to 9,000 units per session).  

Poster #2647: Physician Reaction to Spontaneous Rises in Transferrin Saturation and Serum Ferritin Levels in End Stage Renal Disease Patients
DaVita Clinical Research examined, via a large database of hemodialysis patients receiving phosphate binder therapy over a two-year period, ESA and i
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SOURCE Keryx Biopharmaceuticals, Inc.
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