Navigation Links
Keryx Biopharmaceuticals, Inc. Announces Positive Preliminary Phase 2 Data on KRX-0401 in Patients with Chemo-Insensitive Rare Sarcoma
Date:11/5/2007

Data presented at the 13th Annual Meeting of Connective Tissue Oncology Society held in Seattle, Washington demonstrates clinical activity and

tolerability of perifosine as a single agent in patients with

chemo-insensitive sarcomas

NEW YORK, Nov. 5 /PRNewswire-FirstCall/ -- Keryx Biopharmaceuticals, Inc. (Nasdaq: KERX) today announced that preliminary data demonstrating the tolerability and clinical activity of KRX-0401 (perifosine) in patients with refractory, rare sarcomas was presented on Saturday, November 3, 2007 at the Annual Meeting of the Connective Tissue Oncology Society.

In an oral presentation entitled "A PHASE II TRIAL OF PERIFOSINE IN PATIENTS WITH CHEMO-INSENSITIVE SARCOMAS: PRELIMINARY RESULTS," Dr. Joseph Ludwig Assistant Professor, Dept of Sarcoma, MD Anderson Cancer Center reported on preliminary Phase 2 data in which single agent perifosine demonstrated a 40% overall clinical benefit (Stable Disease > 3 months) in these subsets of patients. Assessment of response was completed by both, RECIST and Choi criteria, and results by sarcoma subtype as follows:

Sarcoma Histology Evaluable PR (Choi) SD > 12 wks

Patients N (%) N (%)

Chondrosarcoma 25 1 (4%) 5 (20%)

Extra-Skeletal Myxoid 13 2 (15%) 5 (38%)

Alveolar Soft Part 10 3 (30%) 3 (30%)

TOTAL 48 6 (13%) 13 (27%)

Perifosine was also well tolerated with the most common grade 1 & 2 adverse events reported as nausea, vomiting, diarrhea and fatigue.

C
'/>"/>

SOURCE Keryx Biopharmaceuticals, Inc.
Copyright©2007 PR Newswire.
All rights reserved

Page: 1 2 3 4 5 6

Related medicine technology :

1. Keryx Biopharmaceuticals to Present at William Blair & Company Small-Cap Growth Stock Conference
2. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
3. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
4. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
5. ADVENTRX Announces Fast Track Designation Granted By the FDA For CoFactor For the Treatment of Metastatic Colorectal Cancer
6. DOV Pharmaceutical, Inc. Announces Successful Phase Ib Results for DOV 21,947
7. Phosphagenics Announces Positive Phase 1b Transdermal Insulin Clinical Trial Results
8. Xenomics Announces Implementation of its First Diagnostic Test for Acute Myeloid Leukemia Into Clinical Practice
9. Emisphere Technologies, Inc. Announces 2007 Second Quarter Financial Results
10. Amicus Therapeutics Announces Second Quarter 2007 Financial Results
11. Genta Incorporated Announces Second Quarter 2007 Financial Results and Corporate Highlights
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/20/2015)... April 20, 2015   Gateway Rehab ... Training Institute today expanded its Naloxone: Increasing Access, ... A $50,000 grant from the Staunton Farm ... possible.  The yearlong research project, ... and their family members upon completion of treatment ...
(Date:4/20/2015)... April 20, 2015 International Isotopes Inc. ... provide shareholders with the following update on its ... Historically, INIS has produced and ... several models of sealed sources for medical and ... radiation therapy, security examination, and radiography.  Due to ...
(Date:4/20/2015)...  Halozyme Therapeutics, Inc. (NASDAQ: HALO ), ... therapies, today shared highlights of new data it ... (AACR) annual meeting. Halozyme also announced plans to ... study in pancreatic cancer, Study 202, next month ... of Clinical Oncology (ASCO). In an ...
Breaking Medicine Technology:Gateway Rehab and the Kenneth S. Ramsey, PhD Research and Training Institute expand Naloxone: Increasing Access, Saving Lives research project to outpatient locations 2Gateway Rehab and the Kenneth S. Ramsey, PhD Research and Training Institute expand Naloxone: Increasing Access, Saving Lives research project to outpatient locations 3International Isotopes Inc. Provides Shareholders With An Update On New Opportunities And Positive Developments Within Its Existing Business Segments 2International Isotopes Inc. Provides Shareholders With An Update On New Opportunities And Positive Developments Within Its Existing Business Segments 3International Isotopes Inc. Provides Shareholders With An Update On New Opportunities And Positive Developments Within Its Existing Business Segments 4International Isotopes Inc. Provides Shareholders With An Update On New Opportunities And Positive Developments Within Its Existing Business Segments 5Halozyme Presents New Preclinical Data At The American Association for Cancer Research Annual Meeting, Announces Clinical Data Presentation At ASCO 2Halozyme Presents New Preclinical Data At The American Association for Cancer Research Annual Meeting, Announces Clinical Data Presentation At ASCO 3Halozyme Presents New Preclinical Data At The American Association for Cancer Research Annual Meeting, Announces Clinical Data Presentation At ASCO 4Halozyme Presents New Preclinical Data At The American Association for Cancer Research Annual Meeting, Announces Clinical Data Presentation At ASCO 5
... Watson Pharmaceuticals, Inc. (NYSE: WPI ) today ... a settlement with Endo Pharmaceuticals, Inc. on outstanding patent ...  Endo filed its lawsuit on March 4, 2010, following ... with the U.S. Food and Drug Administration (FDA) for ...
... Oct. 7 Akorn, Inc. (Nasdaq: AKRX ) ... discuss third quarter 2010 results followed by a Q&A session. ... market opens.Subject: , Akorn Third Quarter 2010 Conference CallDate/Time: ... TimeDomestic Callers: , (888) 215-6895International Callers: , (913) ...
Cached Medicine Technology:Watson Reaches Settlement with Endo Over Opana® ER 2
(Date:4/20/2015)... A recent cross-sectional survey involving fibromyalgia ... top 10 most beneficial therapies for fibromyalgia, no drugs were ... therapies, only approved drugs were named. , “The biggest ... effect is only felt as long as the patient is ... , “On the other hand, aerobic exercise and other non-drug ...
(Date:4/20/2015)... Utah (PRWEB) April 20, 2015 Goodreads ... Employer-Provided Health Insurance: Why It’s Good for You and ... , Paul Zane Pilzer and Rick Lindquist have ... Health Insurance: Why It’s Good for You and Your ... nation’s employer health insurance woes - employer-funded individual health ...
(Date:4/20/2015)... York, New York (PRWEB) April 20, 2015 ... trade association representing the U.S. health insurance industry, ... a result of the recent controversy involving surgical ... a letter to U.S. Senator Robert Casey (D-PA) ... safety concerns surrounding uterine morcellation point to “serious ...
(Date:4/20/2015)... 2015 “ Verus ” was featured ... which features the latest and coolest technology products available ... reporter for NewsWatch, conducted the review and shared with ... of purposes. , According to CNET, at least a ... 2013. It’s unfortunate that smartphones break so easily, but ...
(Date:4/20/2015)... (PRWEB) April 20, 2015 Northern ... Medicare & Medicaid Services introduced their new 5-star “Patient ... Consumer Assessment of Healthcare Providers and Systems) survey of ... patients about their experiences during a recent hospital stay. ... July 1, 2013 through June 30, 2014 can be ...
Breaking Medicine News(10 mins):Health News:Medical Doctor in Huntsville Reveals That Aerobic Exercise Offers Best Results in Fibromyalgia Treatment 2Health News:Zane Benefits Announces Complimentary Book Giveaway On GoodReads: The End of Employer-Provided Health Insurance: Why It's Good for You and Your Company 2Health News:Zane Benefits Announces Complimentary Book Giveaway On GoodReads: The End of Employer-Provided Health Insurance: Why It's Good for You and Your Company 3Health News:Power Morcellator Lawyers at Bernstein Liebhard LLP Comment on Insurance Trade Group’s Call for Greater Regulation of Medical Devices 2Health News:Power Morcellator Lawyers at Bernstein Liebhard LLP Comment on Insurance Trade Group’s Call for Greater Regulation of Medical Devices 3Health News:Power Morcellator Lawyers at Bernstein Liebhard LLP Comment on Insurance Trade Group’s Call for Greater Regulation of Medical Devices 4Health News:Attractive and Durable Phone Cases were Featured on NewsWatch Television 2Health News:Northern Westchester Hospital Named a 5-Star Hospital In Medicare's Patient Satisfaction Rating 2Health News:Northern Westchester Hospital Named a 5-Star Hospital In Medicare's Patient Satisfaction Rating 3
... In times of economic,uncertainty, engaging employees becomes ... becomes much more challenging. Engaged employees feel a,strong ... and that, in,turn, translates into a more productive ... Programs and Activities that Work" delivers,insights into activities ...
... access comprehensive wireless provider ... ... Cross and Blue,Shield in Connecticut today announced the launch of the ... allow,Connecticut members to search for local, in-network doctors and hospitals,through any ...
... dedicated to influencing ... eating habits through education, PARKER, Colo., May 1 ... Council today unveiled Food for Thought from,Parents to Children, ... of three, Chef Gale Gand, and parents across,America. The ...
... inhale as deeply or exhale as fully as normal ... A study of women with a wide range of ... impact of asthma and also mask its severity in ... the changes in respiratory function that occur with asthmatic ...
... Sharing Progress and Promoting Future Strategies, HARRISBURG, Pa., ... Latino Affairs, today opened the PA Latino,Health Care Forum, ... held at the State Museum, is a follow up ... to address health disparities in,Pennsylvania. That summit was the ...
... WASHINGTON, May 1 The following media,advisory was ... Peter I. Buerhaus, PhD, RN, FAAN, Professor of ... Vanderbilt,University Medical Center, Nashville, TN; Karen Donelan, EdM, ... Health Policy,Boston, MA; Beth Ulrich, EdD, RN, FACHE, ...
Cached Medicine News:Health News:Complimentary Excerpt of Employee Engagement: Programs and Activities that Work Available from Best Practices 2Health News:Anthem Blue Cross and Blue Shield in Connecticut Introduces Industry's First Electronic Tool to Help Members Search In-Network Doctors and Hospitals; Transparency Tool to Enable Searches Via Web-Enabled Cell Phones or Hand-Held Devices 2Health News:Parents Can Educate Kids in the Kitchen With Cookbook from Chef Gale Gand and Wheat Foods Council 2Health News:Obesity May Worsen Impact of Asthma 2Health News:GACLA, Department of Health Hosts PA Latino Health Care Forum 2Health News:Will Nursing Shortage Cripple Future Health Care Plans? 2
... Superior Alternative to Bottled Water, The ... alternative for laboratories that currently use bottled ... to purchase, ship and store bottled water, ... - as contamination can be absorbed from ...
... Produces up to 12 L/min of Type ... On Demand, The Super-Q Plus System is ... water which has been pretreated by reverse ... consistently produce ultrapure water quality which exceeds ...
... Laboratory Needs, Synergy systems produce ultrapure water from ... to 1.2 L/min to meet the basic needs ... a dual-wavelength UV lamp (185 nm and 254 ... organic contaminants (< 5 ppb TOC when fed ...
... mechanism for speed, stability and durability. ... display modes, multiple units of measure, ... auto print, and GLP/GMP/ISO output including ... clock. Built-in, motor-driven internal calibration ...
Medicine Products: