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Keck Medicine of USC performs world's 1st implant after FDA approval for groundbreaking epilepsy treatment
Date:12/19/2013

ted 10 patients.

FDA approval of the RNS device came after a randomized clinical trial of 191 patients with drug-resistant epilepsy across 32 clinical sites. The study showed that, by three months after the device was turned on, patients experienced a nearly 38 percent reduction in monthly seizures, compared to a roughly 17 percent reduction in monthly seizures among patients who had the implant turned off. Two years post implant, 55 percent of patients experienced a 50 percent or greater reduction in seizures.

Patients with the RNS device cannot undergo magnetic resonance imaging procedures, diathermy procedures, electroconvulsive therapy or transcranial magnetic stimulation. The energy created from these procedures can be sent through the device and cause permanent brain damage. The most frequent adverse events reported were implant site infection and premature battery depletion.

The USC Center for Neurorestoration

The work that Liu and Heck committed to building USC's Level 4 epilepsy program over the last three years has laid the foundation to establish the Center for Neurorestoration.

"Thanks to Dr. Heck and Dr. Liu's innovation and perseverance, Keck Medicine of USC has a Level 4 epilepsy center, the highest level of medical and surgical evaluation and treatment available for patients with complex epilepsy," said Scott Evans, Pharm.D., M.H.A., CEO of Keck Hospital of USC and USC Norris Cancer Hospital. "The addition of this groundbreaking therapy to our arsenal is testament to our team's dedication to improving the quality of patients' lives."

The center proposes to physically test innovative neural engineering and basic neuroscience to restore neurological circuitry and function in the human brain. The nascent center has already engaged in clinical research partnerships with the USC Viterbi School of Engineering, California Institute of Technology and Rancho Los Amigos National Rehabilita
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SOURCE Keck School of Medicine of the University of Southern California
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