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Karolinska Study Published in Cancer Epidemiology, Biomarkers & Prevention Validates Strong Agreement for VolparaDensity across Mammography Systems from Multiple Manufacturers
Date:7/28/2014

WELLINGTON, New Zealand, July 28, 2014 /PRNewswire/ -- A prospective study conducted by the Karolinska Institute in Sweden has validated the performance of VolparaDensity breast imaging software across multiple vendor platforms and has associated volumetrically assessed breast density measurements to breast cancer risk. Published in Cancer Epidemiology, Biomarkers & Prevention (DOI: 10.1158/1055-9965.EPI-13-1219), the article, "Automated measurement of volumetric mammographic density: a tool for widespread breast cancer risk assessment," was authored by Judith Brand, Kamila Czene, John Shepherd, Karin Leifland, Boel Heddson, Ann Sundbom, Jingmei Li, Keith Humphreys, and Per Hall."Mammographic density is a strong risk factor for breast cancer and an important determinant of screening sensitivity," said Professor Per Hall from the Karolinska's Department of Medical Epidemiology and Biostatistics. "Since the widespread application of mammographic density is highly dependent on the accuracy and reliability of its measurement, we studied the performance of VolparaDensity in a large prospective cohort study," he explains. Professor Hall also noted that, "This is the first large-scale study associating VolparaDensity's assessment results with breast cancer risk."

KARMA (KARolinska MAmmography project for risk prediction of breast cancer) is a prospective cohort study initiated in January 2011 and comprises 70,876 women attending mammography screening or clinical mammography at four hospitals in Sweden. Digital mammography was performed using five different models from three manufacturers (GE Medical Systems, Philips Healthcare and Sectra Imte
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