Navigation Links
Karolinska Institute to Test Vical's Vaxfectin(R) Adjuvant with Preventive Vaccine against HIV Under Sponsorship of Swedish Institute for Infectious Disease Control
Date:8/19/2008

etic versions of genes encoding internal and surface proteins from different HIV subtypes. The combination is designed to provide protection against the most prevalent HIV strains circulating in Europe, Africa and The Americas. The prime-boost approach uses two vaccine components given at different times. The two vaccine components differ in how the genes are packaged. The DNA prime vaccine component contains only the specific gene sequences in a plasmid DNA ring, and cannot reconstitute into an infectious virus. The HIV DNA vaccine was developed by the SMI and the Karolinska Institute in Sweden. The viral vector boost vaccine component uses a Modified Vaccinia Ankara (MVA) virus (the virus that causes cowpox) to shuttle the same non-infectious gene sequences into the body. The boost vaccine component was developed by the NIH and Walter Reed Army Institute of Research, and does not use an adjuvant.

In the first Phase 1 trial, the DNA priming vaccines were delivered with the Biojector(R) 2000 needle-free injection system into either the muscle or the skin. In the next trial, the Vaxfectin(R)-formulated DNA vaccines would be delivered with the Biojector(R) 2000 needle-free injection system into the skin. The MVA boost vaccine is delivered by needle and syringe.

Recently reported preliminary results from Vical's Phase 1 trial of the company's H5N1 pandemic influenza DNA vaccines marked the first time the Vaxfectin(R) adjuvant was tested in humans. Some cohorts were vaccinated by needle and syringe into the muscle and some with the Biojector(R) 2000 needle- free injection system into the muscle. The proposed Karolinska/SMI study would mark the first human test of a Vaxfectin(R)-formulated vaccine delivered by needle-free injection into the skin. Intradermal delivery by needle-free injection and use of the Vaxfectin(R) adjuvant may increase the immune responses to the vaccine.

About Vaxfectin(R)

Vaxfectin(R) was designed by Vical to increase t
'/>"/>

SOURCE Vical Incorporated
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. MabVax Therapeutics Closes Two Licensing Agreements With Sloan-Kettering Institute for Cancer Research
2. New Implant Device Remotely Monitors Heart Failure Patients at Northwestern Memorials Bluhm Cardiovascular Institute
3. Seattles Swedish Cancer Institute First in U.S. to Treat Cancer Patient with Elekta VMAT
4. GlaxoSmithKline Collaborates with National Cancer Institute to Make Large Body of Cancer Cell Genomic Data Available to All Cancer Researchers
5. Banner Alzheimers Institute and Sun Health Research Institute Enrolling Local Patients in Study of Investigational Therapy to Treat Alzheimers Disease
6. Karmanos Cancer Institute Researchers Show Phase I Immunotherapy with Armed T Cells Improve Overall Survival of Metastatic Breast Cancer Patients
7. Tigris Pharmaceuticals Signs CRADA with the National Cancer Institute
8. Poniard Pharmaceuticals Licenses Kinase Inhibitors From The Scripps Research Institute
9. Transgenomic Establishes Collaboration With the National Cancer Institute to Investigate Mitochondrial Genome and Associated Nuclear Genes in Cancer Cell Lines
10. Karmanos Cancer Institute Research Supports Role of Inflammation to Determine Lung Cancer Risk, Particularly in African-American Women
11. Texas Heart(R) Institute at St. Lukes Episcopal Hospital Initiates First Clinical Trial in the World to Treat a Heart Attack Patient with a Special Stem Cell Type
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:7/11/2014)...  Kindred Hospital Houston Northwest, with Wound Care ... its new outpatient wound healing center.  The wound ... chronic, hard to heal wounds. Chronic wounds include ... lower leg wounds related to blood flow issues, ... injury wounds which are complex and demonstrate delayed ...
(Date:7/11/2014)... 2014  Veran Medical Technologies, a U.S. ... positive, cost-effective final results for the initial ... SPiNPerc endobronchial percutaneous biopsy study results support ... biopsy when a traditional bronchoscopic method is ... positive financial outcomes when more can be ...
(Date:7/10/2014)... July 10, 2014  The U.S. Department of Health ... to University Hospitals (UH) Case Medical Center Seidman Cancer ... model aimed at improving care for patients with complex ... project will test a unique model developed at UH ... disease, significant comorbidities, or demonstrated need for high health ...
Breaking Medicine Technology:Kindred Hospital Houston Northwest, With Wound Care Specialists, Opens Outpatient Wound Healing And Hyperbaric Center 2Veran Medical Publishes Lung Cancer Patient Management Study 2University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 2University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 3University Hospitals Case Medical Center Awarded $4.7 Million Grant from U.S. Department of Health and Human Services 4
... 11, 2011 Reportlinker.com announces that ... available in its catalogue: ... New pricing rules set to negatively ... internationally http://www.reportlinker.com/p0360217/Germany-Pharmaceutical-Market-Overview-–-New-pricing-rules-set-to-negatively-impact-drug-sales-both-domestically-and-internationally.html ...
... 11, 2011 Reportlinker.com announces that a new ... The Endoscopy Device Market Outlook ... Introduction This endoscopy device market ... global market, covering endoscopic accessories, instruments, endoscopes, and ...
Cached Medicine Technology:Reportlinker Adds Germany Pharmaceutical Market Overview - New pricing rules set to negatively impact drug sales both domestically and internationally 2Reportlinker Adds The Endoscopy Device Market Outlook to 2015 2
(Date:7/12/2014)... (PRWEB) July 12, 2014 Wright & Schulte ... clients in Just For Men Lawsuits (case #59776/2014), announces ... consumers of reports that allege the popular hair dye, Just ... burns to their face, neck and other areas. In addition ... For Men chemical burns , the advertisements being run by ...
(Date:7/12/2014)... 12, 2014 Maxim Peptide, a website ... are used solely in scientific experiments, is currently celebrating ... in business, Maxim Peptide, which was created by the ... new and updated website that now features a special ... been updated with fascinating articles about peptide research, including ...
(Date:7/11/2014)... Recently, MagicQuinceaneraDresses.com, the popular online supplier of special occasion ... Quinceanera dresses . The company’s new items are specially ... paying a large amount of money. They are all ... The company’s online shop has become a one stop ... In addition to exquisite Quinceanera dresses, it also offers ...
(Date:7/11/2014)... According to new report "C4ISR Market (2014 ... register a CAGR of 2.28% to reach $93.04 ... tables and 76 figures spread through 185 pages ... , Early buyers will receive 10% customization ... report provides market analysis of the global C4ISR ...
(Date:7/11/2014)... PA (PRWEB) July 11, 2014 Butler Mobility ... of Inclined Platform Lifts . Previously the two ... offering five new beautiful earth tone colors as standard colors ... blend well in the home but will enhance the beauty ... choice for any home color scheme or individual décor. , ...
Breaking Medicine News(10 mins):Health News:Just for Men Lawsuit News: TV Campaign Launched by Wright & Schulte LLC to Inform Consumers of the Alleged Association between the Popular Hair Dye and Chemical Burns 2Health News:Just for Men Lawsuit News: TV Campaign Launched by Wright & Schulte LLC to Inform Consumers of the Alleged Association between the Popular Hair Dye and Chemical Burns 3Health News:Just for Men Lawsuit News: TV Campaign Launched by Wright & Schulte LLC to Inform Consumers of the Alleged Association between the Popular Hair Dye and Chemical Burns 4Health News:Maxim Peptide Celebrates Second Anniversary Online with an Updated Website and Special Deals Section 2Health News:Cheap Quinceanera Dresses Now Available At MagicQuinceaneraDresses.com 2Health News:C4ISR Market Estimated to Reach $93.04 Billion by 2019 - New Report by MarketsandMarkets 2Health News:C4ISR Market Estimated to Reach $93.04 Billion by 2019 - New Report by MarketsandMarkets 3Health News:C4ISR Market Estimated to Reach $93.04 Billion by 2019 - New Report by MarketsandMarkets 4Health News:Butler Mobility Products Announces Five New Standard Colors for Their Inclined Platform Lifts 2
... -- The risk of fractures after weight-loss surgery may be ... Prior research has shown that people who undergo surgery to ... for bone fractures. One study, for example, showed a 1.8-fold ... But further analysis showed the risk was actually closer to ...
... thought to accelerate tumor growth in thyroid cancer patients ... for novel cancer therapies, a Mayo Clinic study has ... Clinic researcher Honey Reddi, Ph.D., at the Endocrine Society ... widespread implications in cancer research and endocrinology . ...
... womb can program the potential for adverse health effects in ... on whether the mother or father transmits them, a new ... The Endocrine Society,s 93rd Annual Meeting in Boston. "This ... the womb to excessive levels of stress hormones, known as ...
... 2011 - Additional radiation treatment improves disease free survival ... early breast cancer who have had breast conserving surgery ... results will be presented Monday, June 6 at the ... "These results are potentially practice-changing," said Dr. ...
... -- Medical students who are physically fit are more likely ... new study. Researchers found that medical students who ... physical activity guidelines often felt strongly that being active themselves ... treating. In analyzing certain markers of physical health -- ...
... News) -- College athletes who suffer a concussion may ... concussion is a head injury that can cause headache, ... hearing, as well as difficulty following instructions. "This ... in student-athletes," study author Robert Gardner, a student ...
Cached Medicine News:Health News:Weight-Loss Surgery Linked to Rise in Fracture Risk 2Health News:Fighting cancer with cancer: Mayo Clinic finds promising use for thyroid cancer gene 2Health News:Fetal programming of disease risk to next generation depends on parental gender 2Health News:Breast cancer surgery patients benefit from adding radiation therapy 2Health News:Fit Doctors More Likely to Prescribe Exercise: Study 2Health News:Concussions Tied to Verbal Memory Loss in Young Athletes 2
Bayonet Kerrison Rongeur, ceramic ejector, 9.5 length 40 Fwd, 6.5 working length 165 mm....
Hardy Micro Dissector, bayonet. Working distance 4 1/4" (120 mm). Angled up, tip width: 2 mm....
Papavero-caspar specula for trans-sphenoidal hypophysectomy....
Fahlbusch hypophysectomie instrument, spoon, bayonet-shaped, malleable....
Medicine Products: