Navigation Links
Karmanos Cancer Institute Researchers Show Phase I Immunotherapy with Armed T Cells Improve Overall Survival of Metastatic Breast Cancer Patients
Date:6/1/2008

prove overall survival for metastatic breast cancer," Dr. Lum said. "Although high numbers of remissions were not induced, we may have improved the patients' longevity and quality of life without undue toxicities. The predominant side effects were chills, fever, headaches, and transient hypotension that were controlled with medications and fluid support."

"It appears that infusions of targeted T cells have boosted the immune system to create a more efficient tumor killing machine within the patient's body," he said. "Although the median survival rate for all patients remains undefined, survival rates for the HER2 (0-2+) cohort is 21.3 months." He said that the immunotherapy may be vaccinating the patient's immune system to their own tumors. This is encouraging given that the tumor burden was high in the majority of women who had failed other therapies and the prognosis is poor.

In addition to Dr. Lum, abstract authors include: Zaid Al-Kadhimi, M.D., Associate Director of Immunotherapy, Karmanos Cancer Institute; Cassara Skuba, B.S., Supervisor of Cell Processing Facility, Karmanos Cancer Institute; Rebecca Sandborg, Ph.D., Karmanos Cancer Institute; Ritesh Rathore, M.D., Chief of Hematology/Oncology, Assistant Professor of Medicine, Boston University, Roger Williams Hospital, Providence, RI; Qin Liu, Ph.D., Assistant Professor of Medicine, University of Massachusetts, Worcester, MA; and Co-Leaders of the Karmanos Cancer Center BMT Multidisciplinary team Voravit Ratanatharathorn, M.D. and Joseph Uberti, M.D., Ph.D.

The Phase I Clinical Trial was supported by a National Cancer Institute ROI CA92344 grant, a translational grant from the Leukemia & Lymphoma Society Michigan Life Science Grant, funds from Roger Williams Hospital, Providence RI and funds from the Karmanos Cancer Institute.

The Barbara Ann Karmanos Cancer Institute

The Barbara Ann Karmanos Cancer Institute in Detroit is one of 41 National Cancer Institute (NCI)-designated
'/>"/>

SOURCE The Barbara Ann Karmanos Cancer Institute
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Karmanos Researchers Find Non-Toxic Agents Added to Conventional Chemotherapy Decrease Survival of Colon Cancer Cells
2. Karmanos Researchers Study the Impact of Galectin-3 on Breast Cancer Disparity in Caucasian and Asian Women
3. Karmanos Cancer Institute Research Supports Role of Inflammation to Determine Lung Cancer Risk, Particularly in African-American Women
4. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
5. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
6. Indevus Receives Approvable Letter From FDA for VALSTAR(R) for Bladder Cancer Therapy
7. EpiCept Reports Expansion of Clinical Development For Licensed Cancer Compound
8. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
9. ADVENTRX Announces Fast Track Designation Granted By the FDA For CoFactor For the Treatment of Metastatic Colorectal Cancer
10. Novel Technology Breaks Through Cancer Pain
11. CEL-SCI Secures Manufacturing Facility for Multikine Cancer Drug
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/24/2015)... , und BARCELONA , ... Nr. 4410) iCAD, Inc. (Nasdaq: ICAD ... Bildanalyse, Lösungen für Behandlungsabläufe und Strahlentherapie für ... heute die sofortige Verfügbarkeit des ersten Xoft ... (eBx ® ) System ® in ...
(Date:4/24/2015)... -- Bayer Corporation hosted its annual "Take Your Child to Work ... headquarters.  This is Bayer,s second "Take Your Child To Work ... campus, and Thursday,s event welcomed 230 children ready to see ... Fortunately, for the kids, this was not just another ... "Science For A Better Life," Bayer made sure that "Take ...
(Date:4/24/2015)... , April 24, 2015   Vestagen Technical Textiles, ... VESTEX ® , has recently received two notable innovation ... global competition that recognizes innovations with potential to create ... last night in New York City ... Material Science "Protection & Safety" category. The awards honor ...
Breaking Medicine Technology:Erste Klinik in Spanien setzt das Xoft Electronic Brachytherapy System für die Behandlung von Brustkrebs im Frühstadium, nicht-melanozytärem Hautkrebs und gynäkologischen Krebserkrankungen ein 2Erste Klinik in Spanien setzt das Xoft Electronic Brachytherapy System für die Behandlung von Brustkrebs im Frühstadium, nicht-melanozytärem Hautkrebs und gynäkologischen Krebserkrankungen ein 3Erste Klinik in Spanien setzt das Xoft Electronic Brachytherapy System für die Behandlung von Brustkrebs im Frühstadium, nicht-melanozytärem Hautkrebs und gynäkologischen Krebserkrankungen ein 4Erste Klinik in Spanien setzt das Xoft Electronic Brachytherapy System für die Behandlung von Brustkrebs im Frühstadium, nicht-melanozytärem Hautkrebs und gynäkologischen Krebserkrankungen ein 5Erste Klinik in Spanien setzt das Xoft Electronic Brachytherapy System für die Behandlung von Brustkrebs im Frühstadium, nicht-melanozytärem Hautkrebs und gynäkologischen Krebserkrankungen ein 6Bayer Hosts "Take Your Child to Work Day" 2Bayer Hosts "Take Your Child to Work Day" 3Bayer Hosts "Take Your Child to Work Day" 4VESTEX Wins Innovation Honors from Edison Awards & Apparel Magazine 2VESTEX Wins Innovation Honors from Edison Awards & Apparel Magazine 3
(Date:4/26/2015)... FL (PRWEB) April 26, 2015 India ... pioneered in delivering valuable community services to the Asian ... developmental projects in India for more than two decades. ... hundreds and thousands of subscribers around the world with ... source at that time. The Immigration Law Forum Digest, ...
(Date:4/26/2015)... (PRWEB) April 26, 2015 In an article ... State University evaluated the head-neck biomechanics occurring during the use ... study were able to determine that use of a tablet ... 3 to 5 times - more than when the neck ... for such a study, but pointing out the potential hazards ...
(Date:4/26/2015)... April 26, 2015 The grand celebration got ... by Deb Dettor, CCAR’s Managing Director. Deb then introduced Sandy ... was not in attendance because of his Walk for ... Phil was able to express his gratitude to the volunteers ... for their dedication to carrying out CCAR’s mission. Volunteer ...
(Date:4/25/2015)... DC (PRWEB) April 26, 2015 The ... Seniors (ACE.S) , a national endeavor to prepare nurses ... adults, is a great success, according to a new ... the program's original funding partners. , The project ... of Philadelphia (CCP), under the direction of Elaine Tagliareni, ...
(Date:4/25/2015)... 26, 2015 Avid Collector Andrew Hawley ... Rolling Stones Greensboro Coliseum concert posters. The concert was ... the Stone's Second American Tour. , According to ... out of Baltimore, Maryland. This poster blank was used ... southern cites. Globe uses garish lettering and colors on ...
Breaking Medicine News(10 mins):Health News:North American Telugu Society Bestows Community Service Award to India Network Foundation for Its Generosity and Sponsor of Visitor Health Insurance to Indian Visitors 2Health News:North American Telugu Society Bestows Community Service Award to India Network Foundation for Its Generosity and Sponsor of Visitor Health Insurance to Indian Visitors 3Health News:Avoiding the Pain in the Neck Caused by Overuse of Technology 2Health News:Avoiding the Pain in the Neck Caused by Overuse of Technology 3Health News:Avoiding the Pain in the Neck Caused by Overuse of Technology 4Health News:The Connecticut Community for Addiction Recovery (CCAR) honors its volunteers during National Volunteer Recognition Week. 2Health News:Hartford Foundation Report Details Success of NLN's Advancing Care Excellence for Seniors (ACE.S) Program 2Health News:Hartford Foundation Report Details Success of NLN's Advancing Care Excellence for Seniors (ACE.S) Program 3
... during the past three decades in at least one ... up the habit, according to research presented at the ... Survey, a population-based, serial cross-sectional study of trends in ... in each of its six surveys. Examining the ...
... treat kidney disease; of that population nearly half of ... Dialysis patients are at elevated risk for sudden ... occur because little research has been done to examine ... population. Northwestern Medicine cardiologist Rod Passman, ...
... the months following the death of a spouse or a child, ... heart attack or sudden cardiac death due to an increased heart ... six months, the study authors said. "While the focus at ... the health and welfare of bereaved survivors should also be of ...
... , SATURDAY, Nov. 13 (HealthDay News) -- When implemented, ... (CPR) can dramatically boost survival rates among people being ... expert report. A case report on the effectiveness ... Saturday at the AHA,s annual meeting in Chicago by ...
... Jenifer Goodwin HealthDay Reporter , FRIDAY, Nov. ... to themselves as "stroke centers of excellence" or "chest ... care for stroke and heart attacks. But current ... of the best cardiovascular or stroke care are falling ...
... in 28 years. At 44, he,s one of the youngest ... of "goat" once they,ve completed 20 or more "Macs", the ... sailed the race every year since he was 16. But, ... was in intensive care awaiting heart transplant following a harrowing ...
Cached Medicine News:Health News:Smoking among some adults dropped dramatically in past three decades 2Health News:Smoking among some adults dropped dramatically in past three decades 3Health News:Smoking among some adults dropped dramatically in past three decades 4Health News:Smoking among some adults dropped dramatically in past three decades 5Health News:Smoking among some adults dropped dramatically in past three decades 6Health News:Patients receiving dialysis are at a heightened risk for sudden cardiac death 2Health News:Patients receiving dialysis are at a heightened risk for sudden cardiac death 3Health News:Death of Loved One May Trigger Elevated Heart Rate 2Health News:CPR Guidelines May Lower Out-of-Hospital Death Rate 2Health News:Setting National Hospital Standards Could Boost Cardiac Care 2Health News:Setting National Hospital Standards Could Boost Cardiac Care 3Health News:Myocarditis can attack hearts without warning 2
... is a national reference laboratory and a ... development. ARUP offers an extensive test menu ... in clinical and anatomic pathology. Owned by ... include more than half of the nation's ...
... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
Medicine Products: