Navigation Links
Karmanos Cancer Institute Researchers Show Phase I Immunotherapy with Armed T Cells Improve Overall Survival of Metastatic Breast Cancer Patients
Date:6/1/2008

prove overall survival for metastatic breast cancer," Dr. Lum said. "Although high numbers of remissions were not induced, we may have improved the patients' longevity and quality of life without undue toxicities. The predominant side effects were chills, fever, headaches, and transient hypotension that were controlled with medications and fluid support."

"It appears that infusions of targeted T cells have boosted the immune system to create a more efficient tumor killing machine within the patient's body," he said. "Although the median survival rate for all patients remains undefined, survival rates for the HER2 (0-2+) cohort is 21.3 months." He said that the immunotherapy may be vaccinating the patient's immune system to their own tumors. This is encouraging given that the tumor burden was high in the majority of women who had failed other therapies and the prognosis is poor.

In addition to Dr. Lum, abstract authors include: Zaid Al-Kadhimi, M.D., Associate Director of Immunotherapy, Karmanos Cancer Institute; Cassara Skuba, B.S., Supervisor of Cell Processing Facility, Karmanos Cancer Institute; Rebecca Sandborg, Ph.D., Karmanos Cancer Institute; Ritesh Rathore, M.D., Chief of Hematology/Oncology, Assistant Professor of Medicine, Boston University, Roger Williams Hospital, Providence, RI; Qin Liu, Ph.D., Assistant Professor of Medicine, University of Massachusetts, Worcester, MA; and Co-Leaders of the Karmanos Cancer Center BMT Multidisciplinary team Voravit Ratanatharathorn, M.D. and Joseph Uberti, M.D., Ph.D.

The Phase I Clinical Trial was supported by a National Cancer Institute ROI CA92344 grant, a translational grant from the Leukemia & Lymphoma Society Michigan Life Science Grant, funds from Roger Williams Hospital, Providence RI and funds from the Karmanos Cancer Institute.

The Barbara Ann Karmanos Cancer Institute

The Barbara Ann Karmanos Cancer Institute in Detroit is one of 41 National Cancer Institute (NCI)-designated
'/>"/>

SOURCE The Barbara Ann Karmanos Cancer Institute
Copyright©2008 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Karmanos Researchers Find Non-Toxic Agents Added to Conventional Chemotherapy Decrease Survival of Colon Cancer Cells
2. Karmanos Researchers Study the Impact of Galectin-3 on Breast Cancer Disparity in Caucasian and Asian Women
3. Karmanos Cancer Institute Research Supports Role of Inflammation to Determine Lung Cancer Risk, Particularly in African-American Women
4. Dendreon Announces Publication of Phase 1 Study Highlighting Immunologic and Clinical Activity of Lapuleucel-T (Neuvenge(R)) in Advanced Breast Cancer Patients
5. EDAP Announces Launch of Clinical Study Combining HIFU and Chemotherapy for Localized Aggressive High Risk Prostate Cancer
6. Indevus Receives Approvable Letter From FDA for VALSTAR(R) for Bladder Cancer Therapy
7. EpiCept Reports Expansion of Clinical Development For Licensed Cancer Compound
8. Cephalon Announces Positive Results from a Pivotal Study of FENTORA in Opioid-tolerant Patients with Non-cancer Breakthrough Pain
9. ADVENTRX Announces Fast Track Designation Granted By the FDA For CoFactor For the Treatment of Metastatic Colorectal Cancer
10. Novel Technology Breaks Through Cancer Pain
11. CEL-SCI Secures Manufacturing Facility for Multikine Cancer Drug
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:8/29/2014)... , Aug. 29, 2014 Thoratec Corporation (NASDAQ: ... mechanical circulatory support therapies to save, support and restore ... the 2014 Morgan Stanley Global Healthcare Conference on Wednesday, ... President and Chief Executive Officer, will provide an update ... Time (9:55 a.m., Pacific Daylight Time).   ...
(Date:8/29/2014)... 29, 2014 Research and Markets  has announced ... Insight 2014" report to their offering. ... one of the largest segments of pharmaceuticals industry. The numbers ... the available therapies were unable to meet the market requirements. ... for CNS disorder, especially over the past two decades. The ...
(Date:8/29/2014)... Md. , Aug. 29, 2014  United Therapeutics ... the U.S. District Court for the District of ... favor in the company,s case against Sandoz, Inc. regarding ... Peter Sheridan ruled that U.S. Patent No. ... and enjoined Sandoz from marketing its generic product until ...
Breaking Medicine Technology:US CNS Disorders Drug Pipeline Insight 2014 2District Court Decision Received In Remodulin Patent Case 2
... July 27, 2011 Reportlinker.com announces that ... in its catalogue: India ... Till 2016 http://www.reportlinker.com/p0575381/India-Cardiac-Catheters-and-Guidewires---Market-Trends-Till-2016.html#utm_source=prnewswire&utm_medium=pr&utm_campaign=Surgical_Equipment ... This market report provides vital ...
... 26, 2011 Symmetry Medical Inc. (NYSE: SMA ... orthopaedic device industry and other medical markets, announced today that ... period ending July 2, 2011 before the market opens on ... conference call at 8:00 a.m. ET on Thursday, August 4, ...
Cached Medicine Technology:India Cardiac Catheters and Guidewires - Market Trends Till 2016 2India Cardiac Catheters and Guidewires - Market Trends Till 2016 3Symmetry Medical to Report Second Quarter 2011 Financial Results on August 4, 2011 2
(Date:8/31/2014)... 2014 NutriGold announces that its ... organic fruits and berries, has been approved ... tested, including purity and label claims. , ... Acid from genetically modified and chemically produced corn ... process involves the use of a genetically modified ...
(Date:8/31/2014)... 2014 Market Research Report on ... is a professional and in-depth market survey on ... report firstly reviews the basic information of Cell ... technology. , The report then explores global and ... their product specification, capacity, production value, and market ...
(Date:8/31/2014)... finds that invisible blood in urine may be an early ... for clinicians. , Scientists at the University of Exeter ... age of 60 who had invisible blood in their urine ... bladder cancer. The figure was around half those who had ... of bladder cancer. However, it was still higher than figures ...
(Date:8/31/2014)... August 31, 2014 Adults in the U.S. ... insurance coverage can now use the Quotes Pros website as ... this year can help consumers to find and compare costs ... use of the search tool this year is expected to ... different coverage plans at various price points. The strength of ...
(Date:8/31/2014)... 2014 According to an article posted in ... Times Stronger than Heroin , a new opiate has begun ... more potent than heroin. Known as acetyl fentanyl, this opiate ... many overdoses and emergency room visits among opiate addicts because ... individual might demonstrate the signs of a heroin overdose, they ...
Breaking Medicine News(10 mins):Health News:NutriGold’s Organic Wholefood-Sourced Vitamin C Gets ConsumerLab’s Seal of Approval 2Health News:NutriGold’s Organic Wholefood-Sourced Vitamin C Gets ConsumerLab’s Seal of Approval 3Health News:Cell Harvesting System Industry for Global and Chinese Market Forecasts to 2019 in New Research Report Available at ReportsnReports.com 2Health News:Cell Harvesting System Industry for Global and Chinese Market Forecasts to 2019 in New Research Report Available at ReportsnReports.com 3Health News:Cell Harvesting System Industry for Global and Chinese Market Forecasts to 2019 in New Research Report Available at ReportsnReports.com 4Health News:Invisible blood in urine may indicate bladder cancer 2Health News:Life Insurance Quotes Tool Installed for Public Use at New Insurer Portal Website 2Health News:New Street Drug Found to be Much More Powerful Than Heroin 2Health News:New Street Drug Found to be Much More Powerful Than Heroin 3
... The bastion of the diagnostic company, Medlab, seems to ... an Australian Company, which has been the recipient of ... by the district health boards in Auckland, scheduled to ... Australasia Royal College of Pathologists find themselves in a ...
... have known that a woman’s natural hormone levels can ... study from the University of Southern California// (USC)// has ... women varies by ethnicity and race, and may explain ... study appears in the October issue of Cancer Epidemiology, ...
... index (BMI) received lower scores on cognitive tests than middle-aged ... the// October 10, 2006, issue of Neurology, the scientific journal ... investigated the relationships between BMI and cognitive function in 2,223 ... four cognitive tests. The participants, who were between the ages ...
... to assist HIV infection, may aid the fight against malaria, ... already in use to combat HIV is need of the ... new genre of anti-malarial drugs. ,This is indeed ... and also befalling the HIV afflicted lot with uncanny regularity. ...
... holding a world of cures tucked in its many ... right// ingredients needed to nip breast cancer cells in ... discovered in the compound called indole-3-carbinol (I3C), found in ... cancer cells when combined with conventional chemotherapy drugs. By ...
... change in Egypt in spite of the extensive awareness campaigns, ... flu, since May.// ,A woman in the northern ... aggressive form of bird flu virus, H5N1. ,According ... was suffering from high fever and shortness of breath. She ...
Cached Medicine News:Health News:Ethnic Variations in Hormone Levels May Cause Differences in Breast Cancer Risk 2Health News:High BMI Tied to Poor Cognitive Function in Middle-Aged Adults 2
Supplied sterile in peel-open packages. Intended for one-time use....
Used for percutaneous nephrostomy. Supplied sterile in peel-open packages. Intended for one-time use....
Used for percutaneous nephrostomy. Supplied sterile in peel-open packages. Intended for one-time use....
... Olympuss extensive line of affordable, high-quality ... our high-performance light sources to provide optimal ... light weight and durable design give you ... effectively and efficiently. And each is fully-autoclavable ...
Medicine Products: