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K94 Discoveries, Inc. Announces Seed Financing To Advance Targeted Drug Conjugates To Treat Pancreatic And Other Cancers
Date:9/24/2013

BATON ROUGE, La., Sept. 24, 2013 /PRNewswire/ -- K94 Discoveries, Inc., (K94) a new biotechnology company applying hormone receptor-targeting technology to develop novel cancer therapies, today announced that it has closed a $300,000 seed financing. The financing was provided by BVM Capital, LLC, through its Themelios Ventures II, LP fund.  Ross P. Barrett, Managing Partner of BVM Capital, is interim President of the new company.

K94 Discoveries is developing cancer therapies based on proprietary hormone receptor-targeting discoveries by scientific founder William Hansel, Ph.D., a Professor at the William Hansel Cancer Prevention laboratory at the Pennington Biomedical Research Center of Louisiana State University (LSU). Dr. Hansel found that the luteinizing hormone-releasing hormone (LHRH) receptors present in large numbers on the surface of a wide variety of cancer cells can be harnessed to target cancer drugs.  A version of this technology is also embodied in the targeted cancer drugs being developed by Esperance Pharmaceuticals, a clinical-stage company partly based on Dr. Hansel's inventions

K94 researchers are using a similar approach to develop targeted drug conjugates by combining LHRH with the naturally-occurring plant extract curcumin, which has attracted interest as a potential anticancer agent for decades.  Preclinical studies indicate that curcumin exhibits multiple anticancer properties, and in laboratory tests it promotes cancer cell death and slows the growth of tumors.  However, curcumin's therapeutic potential has been limited by its poor solubility, which the company's novel drug conjugates are designed to overcome.  K94 is initially focusing on pancreatic cancer and is also conducting research in ovarian and breast cancer.

"We are fortunate in Louisiana to have access to extraordinary scientists such as Dr. Hanse
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SOURCE K94 Discoveries, Inc.
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