Navigation Links
Juventas Therapeutics completes enrollment of Phase II STOP-HF study of JVS-100 in patients with symptomatic heart failure
Date:10/28/2013

CLEVELAND, Oct. 28, 2013 /PRNewswire-USNewswire/ -- Juventas Therapeutics, a privately-held clinical-stage company developing novel therapies for treatment of cardiovascular disease, announced today that the company has completed enrollment of the STOP-HF trial. STOP-HF is a double-blinded, placebo-controlled, multi-center trial of its non-viral DNA plasmid therapy JVS-100 for patients with symptomatic heart failure. A total of 93 patients have been enrolled in this trial at 16 academic and community hospitals throughout the United States.

(Logo: http://photos.prnewswire.com/prnh/20131028/DC04442LOGO)

Patients enrolled in STOP-HF had a prior history of a heart attack and years later developed symptomatic heart failure as defined by an ejection fraction less than 40 percent and poor quality of life and exercise tolerance as measured by the Minnesota Living with Heart Failure Questionnaire (MLWHQ) and six minute walk distance (6MWD), respectively. Patients were randomized to placebo or treatment with two different doses of JVS-100.  Therapy was directly delivered to the heart via endo-ventricular injection using the BioCardia Helical Infusion CatheterTM.  In addition to safety, data for several efficacy endpoints is being collected at four months and one-year post-treatment including heart failure related hospitalizations, major adverse cardiac events, and changes in 6MWD, MLWHQ scores, and ejection fraction.

"The patients studied in this trial, on average, have experienced their most recent heart attack nearly a decade prior to treatment and their heart failure symptoms have progressed to a point that their health and ability to perform the activities of daily living are significantly deteriorating despite receiving optimal medical management," states Marc Penn M.D.,
'/>"/>

SOURCE Juventas Therapeutics
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2 3

Related medicine technology :

1. Sorrento Therapeutics Announces Pricing of Public Offering of 4,150,000 Shares of Common Stock and Listing on NASDAQ
2. ISSYS Inc. will showcase its Titan Wireless Implantable Hemodynamic Monitor and its clinical study summary at the 25th Annual Transcatheter Cardiovascular Therapeutics (TCT) Conference (Booth 1638) in San Francisco (October 29 to 31, 2013)
3. Aratana Therapeutics Adds to Commercial Leadership Team
4. Mirati Therapeutics Prices Public Offering Of Common Stock
5. Shareholder Alert: Bronstein, Gewirtz & Grossman, LLC Announces Investigation of Repros Therapeutics, Inc.
6. Cell Therapeutics to Report Third Quarter Financial Results after Market on October 30, 2013
7. Bronstein, Gewirtz & Grossman, LLC Announces Investigation of Osiris Therapeutics, Inc.
8. 3-V Biosciences Presents Positive Data for Novel FASN Inhibitor at the AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics
9. Aratana Therapeutics names Wendy Yarno to its Board of Directors
10. PTC Therapeutics to Showcase Breadth of Pipeline at Upcoming R&D Day
11. Cornerstone Therapeutics Inc. Stockholders Seeking More Money Regarding the Proposed Buyout by Chiesi Farmaceutici S.P.A. Encouraged to Contact Lawyers at Deans & Lyons
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:10/1/2014)... 2014   Plexus Information Systems, Inc. ... Management Systems (AIMS), announced a partnership with ... owned subsidiary of Quality Systems, Inc. and a ... solutions.  Logo - http://photos.prnewswire.com/prnh/20140930/149406 ... This partnership extends the NextGen Healthcare product ...
(Date:10/1/2014)... -- NeuroCall, Inc., ("NeuroCall") announced today that it recently ... services. Dr. Ricardo Garcia-Rivera , Founder and Chief ... that our quality of service has been recognized by ... support and continuity of care to patients of our ... United States ." NeuroCall currently ...
(Date:10/1/2014)... 1, 2014 Quantum Materials Corp (OTCQB:QTMM) ... of photoactive quantum dots for use in ... numerous advantages for solar power generation, the high ... quantum dots with which to develop thin film ... commercial utilization and acceptance. The company is also ...
Breaking Medicine Technology:Plexus IS' Anesthesia Documentation Solution Strengthens NextGen Healthcare Product Offering 2Plexus IS' Anesthesia Documentation Solution Strengthens NextGen Healthcare Product Offering 3NeuroCall Awarded Joint Commission Accreditation 2Quantum Materials Scaling Up Photoactive Quantum Dot Production for Solar Power Generation 2Quantum Materials Scaling Up Photoactive Quantum Dot Production for Solar Power Generation 3
... HARRISBURG, Pa., Dec. 20, 2011  As part of a national ... care facilities with flu vaccination rates for staff of 90 ... www.flufreepa.com . "Increasing vaccination among health care ... and ensure the health of all Pennsylvanians," said Secretary of ...
... 20, 2011 /PRNewswire-Asia-FirstCall/ -- Mindray Medical International Limited (NYSE: ... marketer of medical devices worldwide, announced today an agreement ... Biotech Co., Ltd. ("TDR"). The terms of the agreement ... Mindray,s financial statements. Founded in 1997 and ...
Cached Medicine Technology:Pennsylvania Department of Health Lauds Health Care Facilities for Boosting Flu Vaccination Rates among Workforce 2Mindray Medical to Acquire a Controlling Stake in Hunan Changsha TDR Biotech 2Mindray Medical to Acquire a Controlling Stake in Hunan Changsha TDR Biotech 3
(Date:10/1/2014)... that more than 80 per cent of bowel cancers ... found that medicines called ,JAK inhibitors, halted tumour growth ... present in more than 80 per cent of bowel ... in clinical trials, for diseases including rheumatoid arthritis, psoriasis, ... the second-most common cancer in Australia with nearly 17,000 ...
(Date:10/1/2014)... eye, the brain of a rat and a robot ... a QUT leading robotics researcher. , Dr Michael ... new study uses new computer algorithms to enable robots ... , "This is a very Frankenstein type of project," ... a thing together because we,re taking the eyes of ...
(Date:10/1/2014)... 1, 2014 Patients with increased inflammation, including ... greatly increased risk of depression. For example, a ... hepatitis C virus infection causes depression in approximately ... more commonly known as fish oil, have a ... risk of heart disease and reducing triglyceride levels. ...
(Date:10/1/2014)... research suggests the adage that encourages people to keep ... when it comes to exercise. When walking, staying focused ... to it appear shorter and help people walk there ... this technique to walking while looking around the environment ... of exercise. , "People are less interested in exercise ...
(Date:10/1/2014)... (PRWEB) October 01, 2014 Marriagelifeinsurance.com ... find life insurance for retired couples. , Senior ... provide financial security for their loved ones. A joint ... both insured persons pass away. , Life insurance ... expense life insurance can even be purchased online, as ...
Breaking Medicine News(10 mins):Health News:Eighty percent of bowel cancers halted with existing medicines 2Health News:Robot researcher combines nature to nurture 'superhuman' navigation 2Health News:Omega-3 fatty acids may prevent some forms of depression 2Health News:Keeping your eyes on the prize can help with exercise, NYU study finds 2Health News:Keeping your eyes on the prize can help with exercise, NYU study finds 3Health News:Elderly Life Insurance - Find Life Insurance for Retired Couples! 2
... , Michigan Business and Professional Association Releases ... 29 Eighty-three percent of the owners of small businesses ... plan as a public option for insurance, according to a ... and Professional Association (MBPA) and the Michigan Food ...
... , , BOSTON, Dec. 29 A ... consensus that proper nutrition, regular physical and mental activity, ... improve cognitive skills in healthy adults. Further, the panel ... , The panel, composed of leading scientific experts in ...
... ... Alcohol Recovery (NIFAR®) is launching the next generation of the Regenerate® program in time ... ... its remarkable success in alcohol recovery, National Institute For Alcohol Recovery (NIFAR®) is launching ...
... gurus say recommit each Monday until the habit is gone for good. ... Americans will resolve to quit smoking -- again. Yet many will resume ... American Cancer Society say it doesn,t have to be that way. If ... the following Monday. And recommit to stay quit each Monday thereafter. ...
... TeamStaff, Inc. (Nasdaq: TSTF ), a ... today announced that it has reached a definitive agreement to ... subsidiary, TeamStaff Rx, Inc. to Advantage RN, LLC. TeamStaff Rx ... as an all cash purchase which is expected to close ...
... ... aired episode of “ The Real Housewives of Orange County ,” Dr. Milind Ambe ... discussed rhinoplasty and Orange County breast augmentation with the 19 year-old. ... (Vocus) December 29, ...
Cached Medicine News:Health News:83 Percent of Small Businesses Say 'No' to Health Care Public Option, 89 Percent Say Government Cannot Provide Adequate Health Care 2Health News:83 Percent of Small Businesses Say 'No' to Health Care Public Option, 89 Percent Say Government Cannot Provide Adequate Health Care 3Health News:Expert Panel Reaches Consensus on Our Ability to Improve Cognitive Health 2Health News:Now Millions Suffering With Alcohol Addiction Can Get Breakthrough Recovery in Ultimate Privacy 2Health News:Now Millions Suffering With Alcohol Addiction Can Get Breakthrough Recovery in Ultimate Privacy 3Health News:This New Years, Smokers Get 52 Chances to Stay Quit 2Health News:TeamStaff Announces Agreement to Sell Its Travel Healthcare Subsidiary 2Health News:TeamStaff Announces Agreement to Sell Its Travel Healthcare Subsidiary 3Health News:Newport Beach Plastic Surgeon Educates About the Pros and Cons of Plastic Surgery 2Health News:Newport Beach Plastic Surgeon Educates About the Pros and Cons of Plastic Surgery 3
... Sleep Printing Pulse Oximeter ... to address the growing ... that can easily be ... screening for qualifying or ...
Ergonomic design and intuitive operations. Unique DOX digital SpO2 technology improves performance, even under the most challenging clinical conditions....
... The 8600FO is designed ... of MRI users for patient ... Nonin;s Fiber Optic Sensors and ... burns is eliminated, as well ...
The Avant® 9700 combines flexible alarm options, unparalleled non-volatile memory, and Nonins time-honored technology to give you an easy-to-use and efficient monitor....
Medicine Products: