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Journal of Antimicrobial Chemotherapy Paper Supports Additional Role for Cethromycin as Potential Treatment for Infections Caused by Community- Associated Methicillin Resistant Staphylococcus Aureus (CA-MRSA)
Date:6/25/2008

CHICAGO, June 25 /PRNewswire-FirstCall/ -- Advanced Life Sciences Holdings, Inc. (Nasdaq: ADLS), a biopharmaceutical company engaged in the discovery, development and commercialization of novel drugs in the therapeutic areas of infection, cancer and respiratory diseases, today announced that the Journal of Antimicrobial Chemotherapy has published a paper entitled 'Susceptibility of 170 Isolates of the USA300 clone of MRSA to macrolides, clindamycin and the novel ketolide cethromycin.' The published results demonstrate that cethromycin is highly active in vitro against community- associated methicillin resistant Staphylococcus aureus (CA-MRSA), which is resistant to macrolides and other antibiotics. The results suggest that cethromycin exhibits the ability to treat infections caused by CA-MRSA, further supporting the potential of the drug as a front-line treatment for respiratory tract infections.

(Logo: http://www.newscom.com/cgi-bin/prnh/20080218/ALSLOGO)

Methicillin-resistant Staphylococcus aureus, also called MRSA, is a pathogen that is not killed by many of the antibiotics doctors most commonly prescribe for the treatment of infections. An October, 2007 Centers for Disease Control and Prevention (CDC) report cited that about 94,000 Americans were infected by MRSA in 2005, and this superbug killed more patients than AIDS by contributing to nearly 19,000 deaths that year. Nearly 14% of these infections were due to exposures in the community. Until the late-1990s, MRSA mainly affected patients in hospitals and other healthcare settings. Since that time, a new strain of MRSA has emerged. This new strain is called community-associated MRSA (CA-MR
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SOURCE Advanced Life Sciences Holdings, Inc.
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