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Jentadueto® (linagliptin/metformin hydrochloride) tablets recommended for approval in the treatment of adults with type 2 diabetes in Europe
Date:5/29/2012

have a higher chance of getting lactic acidosis with JENTADUETO if you have kidney problems, liver problems, congestive heart failure that requires medicines, drink alcohol very often, or drink a lot of alcohol in short-term "binge" drinking, get dehydrated (lose a large amount of body fluids), have certain x-ray tests with dyes or contrast agents that are injected into your body, have surgery, have a heart attack, severe infection, or stroke, and are 80 years of age or older and have not had your kidneys tested.

 

Who should not take JENTADUETO?

Do not take JENTADUETO if you:

  • have kidney problems
  • have a condition called metabolic acidosis or diabetic ketoacidosis (increased ketones in the blood or urine)
  • are allergic to linagliptin, metformin or any of the ingredients in JENTADUETO.  Symptoms of any allergic reaction are rash, raised red patches on your skin (hives), and swelling of your face, lips, and throat that may cause difficulty breathing or swallowing.   If you have any symptoms of a serious allergic reaction, stop taking JENTADUETO and call your doctor right away.

What should I tell my doctor before using JENTADUETO?

Before you take JENTADUETO, tell your doctor if you:

  • have kidney problems
  • are going to get an injection of dye or contrast agents for an x-ray procedure.  JENTADUETO will need to be stopped for a short time.  Talk to your doctor about when you should stop JENTADUETO and when you should start JENTADUETO again.
  • have liver problems
  • have heart problems, including congestive heart failure
  • drink alcohol very often, or drink a lot of alcohol in short term "binge" drinking
  • have any other medical conditions
  • are pregnant or planning to become pregnant. It is not know
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SOURCE Eli Lilly and Company; Boehringer Ingelheim
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