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Jennerex Publishes Promising Results from Cancer Clinical Trial of JX-594 in Lancet Oncology
Date:5/21/2008

Tumor responses, safety and long-term survivors validate Jennerex

breakthrough product approach

SAN FRANCISCO and YONGIN-SI, South Korea, May 21 /PRNewswire/ -- Jennerex, Inc. (San Francisco, CA and Ottawa, Ontario), and its South Korean partner Green Cross Corp., announced today that Phase I clinical trial results from its first-in-class lead product JX-594 were published in the premier journal Lancet Oncology. The majority of these end- stage patients with solid tumors had objective tumor destruction and responses following treatment with the cancer biotherapeutic. Half of the JX-594-treated patients survived for more than eight months, well beyond their life expectancies of three to four months, and four patients with tumor responses survived for 11 to over 18 months. Results were especially promising for liver and lung cancer patients. Importantly, treatment with JX-594 was shown to be well-tolerated. A Phase II clinical trial is now underway for JX-594 in liver cancer. The world-wide liver cancer market is estimated at over one billion dollars per year.

"These clinical results with JX-594 are a major step forward for this novel therapeutic approach that Jennerex is pioneering. We are excited by the potential to help the more than ten thousand patients each year who develop liver cancer in the U.S. alone. These desperate patients represent a huge unmet medical need since few effective therapies are available for them. Our team here at UCSD is extremely excited to be a lead site for the current Phase II trial of JX-594 for liver cancer," said Dr. Tony Reid, M.D., Ph.D., Associate Professor and Director of Clinical Investigation at the University of California, San Diego Moores Cancer Center.

"After years of methodical design and development to optimize our products, these results in end-stage patients powerfully validate our commitment to this breakthrough approach. The clinical results were remarkably similar
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SOURCE Jennerex
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