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Jeffrey Epstein, New York Philanthropist, Funds Pioneering Cancer Metastasis Research at Mount Sinai
Date:4/13/2013

NEW YORK, April 13, 2013 /PRNewswire/ -- It is well known that once a tumor metastasizes into the blood stream, the odds of combatting the cancer decline sharply. Early removal of tumors therefore, is an essential way to improve survival. In pivotal research conducted at Mount Sinai Hospital in New York City, surgeon Dr. Jess Ting, breast oncologist, Dr. Kerin Adelson and molecular biologist, Dr. Doris Germain , are looking at how metastasis is not necessarily intrinsic to the tumor but to its micro-environment. The shift in focus is critical Dr. Ting explains because it will be an effective way to identify and stratify those at high risk of metastasis after surgery.

Dr. Ting's research also received an essential financial boost from Jeffrey Epstein, the science philanthropist and financier, who established the Program for Evolutionary Dynamics at Harvard University in 2003.

To obtain a breast tumor's micro-environment, Dr. Ting and his team are using the unique approach of studying fluid emitted from a post-surgery wound site. To date, clinical analysis of a cancer's environment has been the blood, a rich source of disease-related biomarkers. However, blood's complex composition, amongst other factors, is a major challenge for biomarker assays. Other body fluids, including urine, cerebrospina, bronchoalveolar lavage, synovial, amniotic, seminal plasma and interstitial fluids are also rich in disease biomarkers. However, these fluids are only informative in advanced metastatic cancer patients and so their prognostic value in term of disease progression is limited.

Dr. Ting's team saw that wound fluid (emitted from a draining tube), contains all the proteins, growth factors and cytokines that
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SOURCE Jeffrey Epstein VI Foundation
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