Navigation Links
Janssen Research & Development Submits Application to U.S. FDA for XARELTO® (rivaroxaban) to Reduce Secondary Cardiovascular Events in Patients with Acute Coronary Syndrome
Date:12/29/2011

rin: NSAIDs/aspirin are known to increase bleeding; therefore, bleeding risk may be increased when these drugs are used concomitantly with XARELTO®. Promptly evaluate any signs or symptoms of blood loss if patients are treated concomitantly with aspirin, other platelet aggregation inhibitors, or NSAIDs.
  • Clopidogrel: Promptly evaluate any signs or symptoms of blood loss if patients are treated concomitantly with clopidogrel.
  • Drug-Disease Interactions With Drugs That Inhibit CYP3A4 Enzymes and Drug Transport Systems: Use in patients with CrCl 15 mL/min to 50 mL/min who are receiving concomitant combined  P-gp and weak or moderate CYP3A4 inhibitors only if the potential benefit justifies the potential risk (eg, amiodarone, diltiazem, verapamil, quinidine, ranolazine, dronedarone, felodipine, erythromycin, azithromycin, chloramphenicol, and cimetidine).
  • Prophylaxis of Deep Vein Thrombosis
    • Drugs That Inhibit CYP3A4 Enzymes and Drug Transport Systems: When clinical data suggest a change in exposure is unlikely to affect bleeding risk (eg, clarithromycin, erythromycin), no precautions are necessary during coadministration with drugs that are P-gp and CYP3A4 inhibitors.
    • Anticoagulants: Avoid concurrent use of XARELTO® with other anticoagulants due to the increased bleeding risk. Promptly evaluate any signs or symptoms of blood loss.
  • USE IN SPECIFIC POPULATIONS

    • Nursing Mothers: It is not known if rivaroxaban is excreted in human milk. Because of the potential for serious adverse reactions in nursing infants from rivaroxaban, a decision should be made whether to discontinue nursing or discontinue XARELTO®, taking into account the importance of the drug to the mother.
    • Geriatric Use: In clinical trials the
      '/>"/>

    SOURCE Janssen Research & Development, LLC
    Copyright©2010 PR Newswire.
    All rights reserved

    Page: 1 2 3 4 5 6 7 8 9 10 11

    Related medicine technology :

    1. Record Breaking $327 Million Verdict Upheld in Janssen Case and Request for New Trial Denied
    2. Dr. Paul Janssen Award for Biomedical Research Issues Call for Nominations
    3. Pharmacyclics Forms Pact to Develop and Commercialize PCI-32765 for Hematologic Cancers with Janssen Biotech, Inc.
    4. Janssen Pharmaceuticals, Inc. Launches Online Tools on PrescribeResponsibly.com
    5. Janssen Pharmaceuticals, Inc. Announces Definitive Agreement to Divest Ortho Dermatologics Division
    6. Dr. Napoleone Ferrara Wins 2011 Dr. Paul Janssen Award for Biomedical Research
    7. Janssen Products, LP Modifies Prescribing Information for PROCRIT® (Epoetin alfa) in Chronic Kidney Disease
    8. Ortho-McNeil-Janssen Pharmaceuticals, Inc. Voluntarily Recalls One Lot of RISPERDAL® Tablets and One Lot of Risperidone Tablets
    9. Record Breaking $327 Million Verdict Announced in Janssen Case
    10. MHPA Center for Best Practices Receives Sponsorship from Ortho-McNeil Janssen Pharmaceuticals, Inc. to Improve Medicaid Quality, Care Coordination for Serious Mental Illness
    11. Lilly Makes an Irrevocable Offer to Acquire Janssen Animal Health
    Post Your Comments:
    *Name:
    *Comment:
    *Email:
    (Date:7/29/2014)... TAMPA, Fla. , July, 29  2014 ... it has hired John Bournas as ... who announced plans to leave the Society last ... with extensive competencies in the healthcare association industry ... to the Society a clear vision for the ...
    (Date:7/29/2014)... LAUDERDALE, Fla. , July 29, 2014 /PRNewswire-iReach/ ... medical service provider, has launched its Medical ... Program.  These services are tailored to the ... excellent standards prompted industry operators to propose that ... MHG Medical,s new program is intended to ...
    (Date:7/29/2014)... 29, 2014 According to a ... Trauma Fixation Devices Market - Global Forecast, Market Share, ... global orthopedic trauma fixation devices market is estimated at ... grow at a CAGR of 7.2% from 2014 to ... billion in 2020. Browse the Orthopedic Trauma ...
    Breaking Medicine Technology:ISPE Hires Healthcare Association Exec as CEO 2ISPE Hires Healthcare Association Exec as CEO 3MHG Medical Management Services Aims to Change Cruise Industry Standard With New Equipment Maintenance Program 2Orthopedic Trauma Fixation Devices Market is Expected to Reach USD 9.3 Billion Globally in 2020: Transparency Market Research 2Orthopedic Trauma Fixation Devices Market is Expected to Reach USD 9.3 Billion Globally in 2020: Transparency Market Research 3Orthopedic Trauma Fixation Devices Market is Expected to Reach USD 9.3 Billion Globally in 2020: Transparency Market Research 4
    ... 2007 /PRNewswire-USNewswire/ -- The,following statement may be attributed ... Medical Research (CAMR): , "In the face of ... the stroke of his veto pen deliberately to ... well as endanger,the future health and well being ...
    ... - Elixir,Pharmaceuticals, Inc., announced today the publication ... (mitiglinide calcium,hydrate) monotherapy, or combination therapy with ... meals. The data were,published in the Abstract ... Scientific Sessions in Chicago, Illinois.,Glufast is an ...
    Cached Medicine Technology:President Bush Ignores America's Plea for Support of Stem Cell,Research 2Elixir Pharmaceuticals Announces Clinical Data at American Diabetes,Association Conference Highlighting Ability of Glufast to Maintain,Glycemic Control in Patients with Type 2 Diabetes 2Elixir Pharmaceuticals Announces Clinical Data at American Diabetes,Association Conference Highlighting Ability of Glufast to Maintain,Glycemic Control in Patients with Type 2 Diabetes 3Elixir Pharmaceuticals Announces Clinical Data at American Diabetes,Association Conference Highlighting Ability of Glufast to Maintain,Glycemic Control in Patients with Type 2 Diabetes 4Elixir Pharmaceuticals Announces Clinical Data at American Diabetes,Association Conference Highlighting Ability of Glufast to Maintain,Glycemic Control in Patients with Type 2 Diabetes 5
    (Date:7/29/2014)... the nation,s largest interdisciplinary organization devoted to ... Bowers, PhD, RN, FAAN, of the University of Wisconsin-Madison ... Minority Issues in Gerontology Outstanding Mentorship Award. , This ... has exemplified outstanding commitment and dedication to mentoring minority ... presentation will take place at GSA,s 67th Annual Scientific ...
    (Date:7/29/2014)... the nation,s largest interdisciplinary organization devoted to the ... PhD, of Cornell University as the 2014 recipient of ... in Behavioral and Social Gerontology. , This distinguished honor, ... and social gerontology. Individuals who have received their doctorate ... is given by GSA in conjunction with the Margret ...
    (Date:7/29/2014)... The report “Filling Equipment Market by Industry (Food, ... Weight), Process (Manual, Semi-Automatic, Automatic), Product (Solid, Semi-Solid, ... to 2019”, defines the filling equipment market and ... segments with analyses and projections of the market ... of value. It also identifies the driving and ...
    (Date:7/29/2014)... ENCINITAS, Calif. (PRWEB) July 29, 2014 ... prescription drug abuse directly at the source? That’s the ... , an innovative prescription drug abuse risk program developed ... from hundreds of applicants worldwide to be part of ... September 10-12 in San Francisco, CA. The Hive is ...
    (Date:7/29/2014)... INDIANAPOLIS -- With the increasing use of electronic ... a growing demand for a computerized version of ... United States. In a new study, researchers from ... Regenstrief Institute report that substantial work lies ahead ... Future,s guidelines into computerized prompts for physicians, but ...
    Breaking Medicine News(10 mins):Health News:Bowers to receive GSA's 2014 Minority Mentorship Award 2Health News:Löckenhoff earns GSA's 2014 Baltes Foundation Award 2Health News:Filling Equipment Market worth $8 Billion by 2019 - Report by MarketsandMarkets 2Health News:Filling Equipment Market worth $8 Billion by 2019 - Report by MarketsandMarkets 3Health News:Filling Equipment Market worth $8 Billion by 2019 - Report by MarketsandMarkets 4Health News:SafeUseNow Selected to Showcase at TEDMED Hive 2014 2Health News:SafeUseNow Selected to Showcase at TEDMED Hive 2014 3Health News:Study: Pediatric preventive care guidelines need retooling for computerized format 2Health News:Study: Pediatric preventive care guidelines need retooling for computerized format 3
    ... chronically exposed to family turmoil, violence, noise, poor housing ... strain// than other young people. ,However, when ... these negative physiological changes, reports a new study from ... that the cardiovascular systems of youths who are exposed ...
    ... cancer is so much more prevalent in men than women: ... in men than women plays a role in the development ... new types of treatment with the disease. ,In ... Chawnshang Chang, Ph.D., of the University of Rochester Medical Center ...
    ... stent therapy and bypass surgery for coronary artery disease ... event within 30 days after the procedures// , according ... similar outcomes three years after treatment. Patients with coronary ... bypass surgery to reroute the arteries' blood flow or ...
    ... the carotid artery by dental x-rays is not enough evidence ... a review published in the Journal of the American Dental ... leading causes of death and disability among adults in the ... and nutrients to the brain bursts or becomes clogged by ...
    ... head and neck cancer that targets multiple peptides (parts ... tumors. ,The researchers created the vaccine ... is mutated in most cancers and associated with poor ... also expresses unaltered, or "wild-type," p53 peptides in tumors. ...
    ... a dermatologist has a higher survival rate than by a ... to detect// the tumor in its early stages which can ... ,Individuals whose melanoma is diagnosed by a dermatologist may be ... years than those with melanoma diagnosed by a non-dermatologist, according ...
    Cached Medicine News:Health News:Adolescents Exposed to Family Turmoil and Violence Face Stress-related Problems 2Health News:Scientists Find Clue for the Prevalence of Bladder Cancer More in Men 2Health News:Scientists Find Clue for the Prevalence of Bladder Cancer More in Men 3Health News:Scientists Find Clue for the Prevalence of Bladder Cancer More in Men 4Health News:Bypass Surgery, Drug-eluting Stents Possess Similar Risk and Outcome 2Health News:Dental X-rays of Carotid Artery Cannot Estimate Stroke Risk 2Health News:Head and Neck Cancer Vaccine Targets Proteins to Create Immune Response 2Health News:Chances of Survival for Melanoma is High When Detected by Dermatologists 2
    ... reference laboratory and a worldwide leader in ... an extensive test menu of highly complex ... anatomic pathology. Owned by the University of ... half of the nation's university teaching hospitals ...
    ... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
    ... Laboratories is a national reference laboratory and ... and development. ARUP offers an extensive test ... tests in clinical and anatomic pathology. Owned ... clients include more than half of the ...
    ... ARUP Laboratories is a national reference ... laboratory research and development. ARUP offers an ... unique medical tests in clinical and anatomic ... ARUP Laboratories' clients include more than half ...
    Medicine Products: