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Janssen Diagnostics Expands Research Portfolio to Include Next-Generation Sequencing
Date:8/25/2014

RARITAN, N.J., Aug. 25, 2014 /PRNewswire/ -- Janssen Diagnostics, LLC today announced the addition of next-generation sequencing (NGS) to the portfolio of services it provides pharmaceutical and academic researchers. With this announcement, Janssen Diagnostics continues to drive innovative solutions for its lab services customers by expanding its lab services offering in rare cell detection beyond its core competencies: the gold-standard CELLSEARCH® System, proteomics, and fluorescent in situ hybridization.

Janssen Diagnostics has entered into an agreement with Asuragen Inc. enabling them to offer NGS to their customers on Asuragen's proprietary SuraSeq™ panels. This NGS platform allows the rapid analysis of DNA and has proven applicability in oncology research. When used in tandem with the CELLSEARCH® System, this technology can provide researchers with a more comprehensive understanding of tumor biology, drug response, and drug resistance through the capture and interrogation of rare cells (circulating tumor cells, circulating multiple myeloma cells, and others captured via the CELLSEARCH® System).

"We are very pleased to offer NGS services to our research customers," commented Kristen Hollingsworth, Global Business Leader, Janssen Diagnostics, LLC. "Our lab services team is focused on giving researchers tools to identify biomarkers that may be clinically relevant, and track their subjects' status over the course of their clinical trials – we call it 'dynamic monitoring'."

Performing NGS on rare cells can help detect hidden biological processes. As an example, NGS on circulating tumor cells (CTCs) provides additional insights for cancer researchers as studies have demonstrated heterogeneity in information obtained from a primary tumor versus that which is measured in detectable CTCs.

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SOURCE Janssen Diagnostics, LLC
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