Navigation Links
Janssen Announces Initiation Of Phase 3 Development Program For Sirukumab In Rheumatoid Arthritis
Date:8/23/2012

CORK, Ireland and SPRING HOUSE, Pa., Aug. 23, 2012 /PRNewswire/ -- Janssen Biologics (Ireland) announced today it has initiated the Phase 3 development program for sirukumab (CNTO 136) as part of a collaboration with GlaxoSmithKline plc (GSK).  Sirukumab is a human anti-interleukin (IL)-6 monoclonal antibody being studied for the treatment of adults with moderately to severely active rheumatoid arthritis (RA). 

"We are focused on advancing treatment options for chronic, debilitating autoimmune diseases such as rheumatoid arthritis," said Jerome A. Boscia, M.D., Vice President, Head of Immunology Development, Janssen Research & Development, LLC.  "We are pleased to be collaborating with GlaxoSmithKline on the clinical development of sirukumab, a protein therapeutic that we believe may represent an important treatment option for immunological diseases in the future."

The two studies comprising the Phase 3 program are:

  • SIRROUND-T: A multicentre, randomised, double-blind, placebo-controlled, parallel group study of sirukumab administered subcutaneously in subjects with active RA despite anti-tumor necrosis factor (TNF)-alpha therapy. The primary objective is to assess the efficacy of sirukumab as measured by the reduction of the signs and symptoms of RA in subjects with active RA who are refractory or intolerant to anti-TNF-alpha agents.

 

  • SIRROUND-D: A multicentre, randomised, double-blind, placebo-controlled, parallel group study of sirukumab administered subcutaneously in subjects with active RA despite disease modifying anti-rheumatic drug (DMARD) therapy. The primary objective is to assess the efficacy of sirukumab as measured by the reduction of the signs and symptoms of RA and inhibition of radiographic progression in subjects with active RA who are refractory to DMARDs.

About Sirukumab (CNTO 136)
Sir
'/>"/>

SOURCE Janssen Research & Development, LLC
Copyright©2012 PR Newswire.
All rights reserved

Page: 1 2

Related medicine technology :

1. Janssen Research & Development Submits New Drug Application to U.S. FDA for Canagliflozin to Treat Patients with Type 2 Diabetes
2. Janssen Research & Development Submits XARELTO® (rivaroxaban) to U.S. FDA for the Treatment and Prevention of Recurrent Venous Thromboembolism
3. WorkSmart MD Announces Expansion of its Synergy Billing Division to Help Community Health Centers
4. BiOptix Announces Fall 2012 Tradeshow and Symposia Schedule
5. Interventional Spine Announces its 75th Patient Treated with the PerX360 Percutaneous Spinal Fusion Technology
6. Precision Automation Expert DWFritz Automation Announces Website Launch www.DWFritz.com
7. CPhI South America Expands Offering for 2013, Announces Co-Location with Food Ingredients South America
8. EFJohnson Announces Impact Partner Dealer Program
9. Aethlon Medical Announces Renewal of DARPA Dialysis-Like Therapeutics Contract
10. Kallo Announces Purchase Order For Its Specialist EMR - EMCURx
11. CryoLife Announces Initiation of Quarterly Cash Dividend
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:11/26/2014)... FRANCISCO , Nov. 25, 2014  goBalto, Inc., ... has been recognized as a winner of Red Herring,s ... a Global Top 100 North America award in 2013, ... international technology landscape. Red Herring,s Top 100 ... identifying promising new companies and entrepreneurs. Red Herring editors ...
(Date:11/26/2014)... , Nov. 25, 2014  Medtronic,s roughly ... has been widely discussed in the media for ... creating a stronger leading player in one of ... Information.  The healthcare market research firm said  the ... feature a diverse set of solutions spanning inpatient ...
(Date:11/26/2014)... Colo. , Nov. 25, 2014   Heska Corporation ... "Heska" or the "Company"), a provider of advanced veterinary ... Robert Grieve , Executive Chair, will attend The Benchmark ... 2014. The one-on-one conference will be held at The Palmer ... from 8 a.m. to 2:30 p.m. Please email ...
Breaking Medicine Technology:goBalto Selected as a 2014 Red Herring Top 100 Global Company 2goBalto Selected as a 2014 Red Herring Top 100 Global Company 3Medtronic - Covidien: Beyond Taxes, Deal Will Create Patient Monitoring Power, according to Kalorama Information 2Medtronic - Covidien: Beyond Taxes, Deal Will Create Patient Monitoring Power, according to Kalorama Information 3Heska to Attend Benchmark Micro Cap Discovery Conference 2
... COCONUT GROVE, Fla., April 9, 2012 Med-Tek a developer ... for patients, physicians, employers and their constituents today announces ... According to the United ... through 2004 individuals suffering from ...
... 2012 C8 MediSensors, Inc. ( www.c8medisensors.com ), the ... with diabetes, announced today that it has filed for ... Glucose Monitor™ in Europe. The monitor is currently an ... "The European Union has over 30 ...
Cached Medicine Technology:Med-Tek Launches the First Evidenced Based Opioid Management Program (OMP) 2C8 MediSensors Files for CE Mark Approval, Advancing Plans for 2012 Product Introduction In Europe 2
(Date:11/27/2014)... CA, (PRWEB) November 26, 2014 ... browser-based presentation platform, focused on increasing audience engagement ... Britannic Technologies. Lintelus’ software platform includes a multitude ... and presenter in a collaborative, interactive multi-screen environment. ... and the presentation in real time on their ...
(Date:11/27/2014)... 2014 Serious Buyer, Andrew Hawley from ... Hendrix Tuscaloosa Memorial Coliseum concert posters. Between 1969 and ... the University of Alabama. Jimi Hendrix started the concert ... started with Gary Weinberger who was a freshman at ... Council. The council was responsible for bringing music acts ...
(Date:11/26/2014)... La Mirada, CA (PRWEB) November 26, 2014 ... to the community of Perris , and it ... Martin Del Campo specializes in the field of Occupational ... injured employees. Healthpointe’s Occupational Medicine specialist delivers quality care ... on workplace safety and health. , As an ...
(Date:11/26/2014)... 27, 2014 Recently, DressVe , ... occasion dresses, has unveiled its 2014 Cyber Monday Sales. ... new dresses, up to 90 percent off. The special ... 3. Free delivery is provided for orders above $69. ... dresses, shoes, handbags and other fashion accessories. The mission ...
(Date:11/26/2014)... (PRWEB) November 27, 2014 Sweetdressy.com, the ... introduced its newest selection of cheap prom dresses for ... discounted prices. The prom dresses from Sweetdressy.com are very ... dresses at the website of Sweetdressy.com now. , ... the way that offering the best items and best ...
Breaking Medicine News(10 mins):Health News:Lintelus Showcases its Feature-Rich Presentation Technology Solution at Convergence Summit’s Annual Event in London 2Health News:Serious Buyer Announces His Search For Vintage 1969 Jimi Hendrix Tuscaloosa Memorial Coliseum Concert Posters 2Health News:Healthpointe now offering Occupational Medicine in their Perris Medical Clinic 2Health News:Healthpointe now offering Occupational Medicine in their Perris Medical Clinic 3Health News:DressVe.com: Best 2014 Special Monday Sales Online 2Health News:Cheap Prom Dresses For Ladies Introduced At SweetDressy.com 2
... to the Centre asking it to explain the basis ... cent reservation was taken//. ,With the deadlock on ... to examine the government's controversial move to provide 27 ... in higher educational institutions. ,Questioning the basis ...
... 1 diabetes to alopecia, from which the imbalance of killer ... ,By age 5, out of three problems – ... membrane and adrenal gland insufficiency, two will result in a ... about 16 autoimmune diseases in a lifetime. ,The ...
... administration in WHO, to an agreement that will permit the revamp ... in this field, which will enable affordable drugs as per the ... of drug research and development, which will in turn pave the ... ,This resolution is being considered as a breakthrough by ...
... shown some alarming world statistics regarding the use of tobacco ... 13-15 year olds consume tobacco and its products. , ... the World Health Organization's World No Tobacco Day; on May ... deadly in any form or disguise,' conveying cigarette smoking in ...
... is launching a smart and innovative health card for sex ... 500 sex workers are set to benefit from this which ... this scheme is to start with as many as 500 ... the brainchild of Karnataka Health Promotion Trust (KHPT), AMSS and ...
... Scottish Executive and cash-strapped NHS health boards are in San ... to try to hire 20 physicians' assistants. They are trying ... the shortage of physicians. ,With hundreds of junior ... facing deportation because of changes in immigration rules, this news ...
Cached Medicine News:Health News:Supreme Court Verdict Gives Hope to Striking Medicos 2Health News:Autoimmune Diseases – Newer Preventive Measure 2Health News:Autoimmune Diseases – Newer Preventive Measure 3Health News:Sex Workers To Have Smart Health Card 2Health News:Plans Of Recruiting Pas From America Causes Displeasure In Scotland 2Health News:Plans Of Recruiting Pas From America Causes Displeasure In Scotland 3
... simplified focusing guidance system has made ... use of its type. Technicians can ... with a minimum of instruction. The ... lines to focus first. A flashing ...
... of electronic refractors. The TRS replaces your standard ... a keypad that is small enough to sit in ... Chart Projector. The TRS is programmable so that at ... moved for you, taking you to your next refraction ...
The Electric H-Base Table is for heavier instruments, or for those who prefer electric elevation. The electric table easily accepts a slit lamp, a single tabletop, or a double tabletop, just as the M...
The Manual Table Base is elevated with an easy to reach elevating wheel for smooth operation. The table base will accept a slit lamp, a single table top, or a double tabletop for more than one instru...
Medicine Products: