Navigation Links
JDRF and Amylin Partner to Investigate Co-Formulating Two Hormones for Treatment of Type 1 Diabetes
Date:5/10/2011

omes a daily balancing act," said Matthew Riddle, M.D., Professor of Medicine, Division of Endocrinology, Diabetes, & Clinical Nutrition, Oregon Health & Science University. "Pramlintide may provide additional benefit for these patients by stabilizing their blood sugar levels, so they spend more time in the normal glucose range."

Currently, patients who use pramlintide must separately administer their daily insulin therapy, either through injections or an insulin pump. A co-formulated therapy that harnesses the benefit of both hormones might better mimic the natural physiology of the pancreas and simplify dosing decisions.

"Ultimately, it might reduce the complexity of daily treatment for patients who are working hard to manage this disease, and improve their ability to achieve treatment goals," continued Dr. Riddle.

About the Research Collaboration

This is the second research collaboration between JDRF and Amylin to advance innovative treatments for people with type 1 diabetes. This collaboration, consisting of formulation and clinical work, will investigate whether a fixed ratio of pramlintide and insulin can effectively help treat type 1 diabetes. The formulation research will assess the feasibility of co-formulating pramlintide and insulin (both currently administered using separate injections) as a single injection. An optimal ratio of pramlintide and insulin will be identified through modeling work.  In a series of up to three clinical proof-of-concept studies, the program will also investigate the optimal pramlintide:insulin dose ratios, and determine whether delivering pramlintide and insulin in this fixed ratio, can improve glucose control and optimize treatment of type 1 diabetes compared with insulin alone.

The collaboration between JDRF and Amylin is part of JDRF's Industry Discovery and Development Partnership (IDDP) program to accelerate research that will lead to better treatments and a cure for
'/>"/>

SOURCE Amylin Pharmaceuticals, Inc.; Juvenile Diabetes Research Foundation
Copyright©2010 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Amylin Pharmaceuticals to Present at the Bank of America 2011 Healthcare Conference
2. Amylin Pharmaceuticals to Present at the Deutsche Bank 36th Annual Healthcare Conference
3. Amylin Pharmaceuticals Reports First Quarter Financial Results
4. Amylin to Present Data Showing Investigational Metreleptin Treatment Led to Long-Term Improvements in Diabetes and Lipid Control in Patients with Lipodystrophy
5. Amylin and Takeda Voluntarily Suspend Clinical Activities in Obesity Trial
6. Amylin Pharmaceuticals to Present at the Barclays Capital 2011 Global Healthcare Conference
7. Amylin Pharmaceuticals to Present at the 2011 ISI Annual Conference
8. Amylin Pharmaceuticals Reports 2010 Financial Results
9. Amylin Pharmaceuticals to Webcast Year-End Financial Results
10. Amylin Pharmaceuticals to Present at the 29th Annual J.P. Morgan Healthcare Conference
11. Amylin Submits Clinical and Nonclinical Sections of Rolling Biologics License Application for Metreleptin to Treat Rare Forms of Lipodystrophy
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:12/17/2014)... 2014  Beamz Interactive, Inc. (OTCQB: BZIC), a ... announced that it has signed an agreement with ... of innovative prosthetic, orthotic and assistive technology products ... agreement, RSL Steeper will promote and supply the ... use within UK residential care facilities through its ...
(Date:12/17/2014)... , Dec. 17, 2014  IGI Laboratories, Inc. (NYSE ... closing of its offering of $125 million aggregate principal ... "Notes").  The Notes were offered and sold only to ... Securities Act of 1933, as amended (the "Securities Act"). ... rate of 3.75% per year, payable semiannually in arrears ...
(Date:12/17/2014)... 17, 2014 PCCA received the Autism ... http://bit.ly/1382OkS ) program seal for best practices in ... highlights medical practices, materials and goods that meet ... Children affected by autism often have unique ... by ingredients found in food and medicine – ...
Breaking Medicine Technology:Beamz Interactive, Inc. Signs UK Distribution Agreement with RSL Steeper Limited 2Beamz Interactive, Inc. Signs UK Distribution Agreement with RSL Steeper Limited 3IGI Laboratories Announces Closing of $125 Million of 3.75% Convertible Senior Notes Due 2019 2IGI Laboratories Announces Closing of $125 Million of 3.75% Convertible Senior Notes Due 2019 3IGI Laboratories Announces Closing of $125 Million of 3.75% Convertible Senior Notes Due 2019 4Parents Of Children With Autism Spectrum Disorder Have New Options When Administering Medications 2Parents Of Children With Autism Spectrum Disorder Have New Options When Administering Medications 3
... 19, 2012 Uroplasty, Inc. (NASDAQ: UPI ) ... third quarter of fiscal 2012 ended December 31, 2011, at ... will host a conference call to discuss these results on ... p.m. Central Time). David Kaysen, President and Chief Executive Officer, ...
... MINNEAPOLIS, Jan. 19, 2012 /PRNewswire-iReach/ -- Today, ... the 4th Annual TripleTree iAwards for Wireless Health ... impactful mobile and wireless solutions in the healthcare industry. ... be accepted through March 30, 2012.  Each application will ...
Cached Medicine Technology:Uroplasty to Issue Third Quarter 2012 Financial Results on January 26, 2012 2Call for Submissions: 2012 TripleTree iAwards for Wireless Health 2Call for Submissions: 2012 TripleTree iAwards for Wireless Health 3
(Date:12/19/2014)... TX (PRWEB) December 19, 2014 ... a shifting, capital equipment market that is saturated ... impressive safety and efficacy as well as non-invasive ... they were first introduced to the healthcare market. ... the development of MRI safe technologies have greatly ...
(Date:12/19/2014)... 2014 From November 24, 2014, Siddhi ... the year 2014 in its Goa retreat . This ... the Indian winters, from November to March, Siddhi Yoga will ... of Arambol, Goa. The Goa training sessions will conclude in ... yoga teacher training, the 10th intake is also a ...
(Date:12/19/2014)... (PRWEB) December 19, 2014 The ... ski club in Southern Vermont’s Deerfield Valley, announced today ... inspired by classic rock songs. , Three time ... with a private concert followed by a trail naming ... new trail names include: “I’m Alright” the theme song ...
(Date:12/19/2014)... Dotinga HealthDay Reporter ... including ibuprofen, might slightly reduce your risk of developing ... of ibuprofen (Advil, Motrin) and naproxen (Aleve) appear to ... 15 percent, the researchers concluded after reviewing nine prior ... sun exposure. These painkillers "have potential ...
(Date:12/17/2014)... (PRWEB) December 17, 2014 Dr. Myo Nwe ... Weight Loss Diet of the Future” and co-founder of the ... her book, Dr. Nwe takes a broad look at the ... hold up under scientific scrutiny. On film and in television ... emphasized mostly toward the social aspects and played for basic ...
Breaking Medicine News(10 mins):Health News:Magnetic Resonance Imaging Systems Market Analysis and Forecast to 2020 Report at RnRMarketReserach.com 2Health News:Magnetic Resonance Imaging Systems Market Analysis and Forecast to 2020 Report at RnRMarketReserach.com 3Health News:Magnetic Resonance Imaging Systems Market Analysis and Forecast to 2020 Report at RnRMarketReserach.com 4Health News:Siddhi Yoga’s 10th intake of YTT started in Goa on November 24, 2014 2Health News:Siddhi Yoga’s 10th intake of YTT started in Goa on November 24, 2014 3Health News:The Hermitage Club Officially Names Four Ski Trails after Iconic Rock Songs by Grammy Award Winner Kenny Loggins 2Health News:Common Painkillers May Help Prevent Certain Skin Cancers, Study Finds 2Health News:Common Painkillers May Help Prevent Certain Skin Cancers, Study Finds 3Health News:Obesity Should Not Be a Hollywood Punchline, Weight Loss Doc Says 2
... OAK BROOK, Ill. April 25, 2011 A ... acid suppression is a safe and effective method to ... adenocarcinoma (cancer) or high-grade dysplasia of the esophagus developed ... largest published series and longest follow-up of patients with ...
... , MONDAY, April 25 (HealthDay News) -- Some college students ... reruns during the TV writers, strike of 2007-2008, a new ... use television for companionship -- as opposed to simply for ... characters on the tube, the study authors noted. "We ...
... R.I. [Brown University] A new study of sexual ... that HIV-positive people take almost as much risk in ... HIV-negative or don,t know their status, as when they ... time, HIV-positive partners who are on antiretroviral therapy and ...
... Ga. Decreasing blood levels of a protein that ... could help children avoid type 1 diabetes, researchers say. ... levels of interleukin-1 receptor antagonist, or IL-1ra, in children ... risk for type 1 diabetes. They also are looking ...
... Pasteur, the vaccines division of the sanofi-aventis Group (EURONEXT: ... Food and Drug Administration (FDA) has granted licensure to ... (Meningococcal [Groups A, C, Y and W-135] Polysaccharide Diphtheria ... infants and children 9 months through 23 months of ...
... MONDAY, April 25 (HealthDay News) -- Acupuncture might help ... patients while they,re on hormone therapy, a small study ... ancient Chinese discipline relieves hot flashes, and only 14 ... researchers at New York Methodist Hospital and Weill Cornell ...
Cached Medicine News:Health News:Long-term follow-up shows multipolar electrocoagulation ablation effective for Barrett's esophagus 2Health News:Long-term follow-up shows multipolar electrocoagulation ablation effective for Barrett's esophagus 3Health News:Long-term follow-up shows multipolar electrocoagulation ablation effective for Barrett's esophagus 4Health News:Some TV Fans 'Distressed' Without Favorite Shows: Study 2Health News:Fighting HIV in South Africa should focus on couples, study finds 2Health News:Fighting HIV in South Africa should focus on couples, study finds 3Health News:Protein levels could signal that a child will develop diabetes 2Health News:Sanofi Pasteur announces FDA approval of menactra meningococcal conjugate vaccine indication for infants 2Health News:Acupuncture May Help Ease Hot Flashes Tied to Prostate Cancer Treatment 2
Lacrimal Cannula, Curved - Closed End, CurvedSize: 25g x 1-1/2"....
PremierEdge™ Slit Knives....
Interchangeable design allows you to select a single handpiece and change tips during the procedure. Universal connector. Disassembles for easy cleaning. Tips can rotate 360 degrees to re-orient port...
Interchangeable design allows you to select a single handpiece and change tips during the procedure. Universal connector. Disassembles for easy cleaning. Tips can rotate 360 degrees to re-orient port...
Medicine Products: