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Isis Reports Financial Results and Highlights for Third Quarter 2011
Date:11/7/2011

all measured atherogenic lipids with a safety profile consistent with the Phase 3 studies.
  • Genzyme reached an agreement with the FDA on the design of the FOCUS FH study via a Special Protocol Assessment (SPA).  
  • Isis initiated Phase 1 studies on ISIS-GCGRRx and ISIS-GCCRRx.
  • Isis added a new drug candidate, ISIS-AATRx, to its pipeline in Isis' GSK collaboration.  Isis earned a $5 million milestone payment.
  • Isis and CHDI renewed their collaboration to discover and develop an antisense drug for the treatment of Huntington's Disease.
  • Isis filed a patent infringement lawsuit against Santaris Pharma based upon Santaris' commercial activities providing antisense drugs and antisense drug discovery services to several pharmaceutical companies.

  • Conference CallAt 4:30 p.m. Eastern Time today, November 7, Isis will conduct a live webcast conference call to discuss the earnings release and related activities.  Interested parties my listen to the call by dialing 888-396-2384 and refer to passcode "ISIS 2011", or access the webcast at www.isispharm.com.  A webcast replay will be available for a limited time at the same address.

    ABOUT ISIS PHARMACEUTICALS, INC.Isis is exploiting its leadership position in antisense technology to discover and develop novel drugs for its product pipeline and for its partners.  Isis' broad pipeline consists of 25 drugs to treat a wide variety of diseases with an emphasis on cardiovascular, metabolic and severe and rare/neurodegenerative diseases, and cancer.  Isis' partner, Genzyme, plans to commercialize Isis' lead product, mipomersen, following regulatory approval, which is expected in 2012.  Isis' patents provide strong and extensive protection for its drugs and technology.  Additional information about Isis is available at www.isispharm.com.

    ISIS PHARMACEU
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    SOURCE Isis Pharmaceuticals, Inc.
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