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Isis Reports Financial Results and Highlights for First Quarter 2013
Date:5/7/2013

t high-quality partners for our severe neurological disease and cancer programs to augment our own efforts in these two newest areas of our pipeline.  We have been successful implementing this strategy.  Since January of last year, we have initiated five new partnerships that involve neurological diseases and cancer, bringing in more than $125 million in upfront payments and adding partners that are significantly enhancing our drug discovery and development efforts in these therapeutic areas," continued Ms. Parshall.  "We believe that our partnerships are structured to provide the best support and ultimately the best value for each drug.  Our partnership with Roche for our Huntington's disease program is a very good example of how we benefit from the expertise and resources that our partner brings while we maintain control over the discovery and early development of the program.  We look forward to broadly evaluating this program with Roche and developing antisense drugs to treat Huntington's disease."Corporate and Drug Development Highlights

  • Isis and Genzyme were successful in bringing KYNAMRO to the market in the United States for patients with HoFH.  These patients are at high cardiovascular risk and may not be able to reduce their LDL-C sufficiently with currently available lipid-lowering therapies. 
  • Genzyme launched KYNAMRO in the United States for the treatment of patients with HoFH.
  • Isis received a $25 million milestone payment from Genzyme related to the marketing approval of KYNAMRO by the FDA.
  • Genzyme continues to enroll the FOCUS FH study, which is designed to provide 60-week safety and efficacy data in FH patients to support an additional regulatory filing.  Genzyme reached an agreement with the FDA on the design of the FOCUS FH study via a Special Protocol Assessment, or SPA.
  • Isis and its investigators reported positive data from a number of drugs in Isis' pipeline.
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  • SOURCE Isis Pharmaceuticals, Inc.
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