Navigation Links
Isis Pharmaceuticals Initiates Phase 3 Study of ISIS-SMN Rx in Infants with Spinal Muscular Atrophy
Date:8/1/2014

sed from Cold Spring Harbor Laboratory and the University of Massachusetts Medical School.

ABOUT SMA
SMA is a severe genetic disease that affects approximately 30,000-35,000 patients in the United States, Europe and Japan. SMA is caused by a loss of, or defect in, the survival motor neuron 1 (SMN1) gene leading to a decrease in the survival motor neuron (SMN) protein. SMN is critical to the health and survival of nerve cells in the spinal cord responsible for neuromuscular growth and function. One in 50 people, the equivalent of about 6 million people in the United States, are carriers of a defective SMN1 gene, which is unable to produce fully functional SMN protein. Carriers experience no symptoms and do not develop the disease. However, when both parents are carriers, there is a one in four chance that their child will have SMA. The severity of SMA correlates with the amount of SMN protein. Infants with Type I SMA, the most severe form of the disease, produce very little SMN protein and have a life expectancy of less than two years. Children with Type II have greater amounts of SMN protein but still have a shortened lifespan and are never able to stand independently. Children with Type III have a normal lifespan but accumulate life-long physical disabilities as they grow.

ABOUT ISIS and BIOGEN IDEC
Biogen Idec and Isis have established four collaborations focused on leveraging antisense technology to advance the treatment of neurological and neuromuscular disorders.  This alliance combines Isis's expertise in antisense technology to evaluate potential neurological targets and discover antisense drugs with Biogen Idec's capability to develop therapies for neurological disorders.  Isis is primarily responsible for drug discovery and early development of antisense therapies.  Biogen Idec has the option to license each antisense
'/>"/>

SOURCE Isis Pharmaceuticals, Inc.
Copyright©2014 PR Newswire.
All rights reserved

Page: 1 2 3 4 5

Related medicine technology :

1. Inovio Pharmaceuticals to Host Second Quarter 2014 Financial Results Call on August 11, 2014
2. Arena Pharmaceuticals Provides Corporate Update and Reports Second Quarter 2014 Financial Results
3. Auxilium Pharmaceuticals, Inc. To Announce Second Quarter 2014 Results On August 7, 2014
4. Rock Creek Pharmaceuticals Provides Update of its European Drug Development Regulatory Strategy and selects Quotient Clinical for its early development programs
5. Valeant Pharmaceuticals Reports Second Quarter 2014 Financial Results
6. Auxilium Pharmaceuticals, Inc. Announces XIAFLEX Milestone: Partner Asahi Kasei Pharma Corporation Completes Regulatory Submission For Dupuytrens Contracture In Japan
7. Eisai and Arena Pharmaceuticals Announce Publication of Post-Hoc Analyses of Lorcaserin Phase 3 Clinical Trial Results in Obesity
8. Access Pharmaceuticals Featured On OncLive.com
9. Immune Pharmaceuticals Commences Patient Screening For Bertilimumab Phase II Clinical Trial In Bullous Pemphigoid, A Rare Auto-Immune Disease Of The Skin
10. Alexza Pharmaceuticals Announces Participation in Upcoming Investor Conferences
11. Cloud Pharmaceuticals Receives Phase I NSF SBIR Grant Valued at $150,000
Post Your Comments:
*Name:
*Comment:
*Email:
(Date:4/17/2015)... and Markets ( http://www.researchandmarkets.com/research/lmsnqn/medical_equipment ) has announced ... Leasing - Global Strategic Business Report" report to ... markets for Medical Equipment Rental and Leasing in US$ ... US, Japan , Europe ... estimates and forecasts are provided for the period 2014 ...
(Date:4/17/2015)... DIEGO , April 17, 2015  Trovagene, ... diagnostics, announced today that clinical data presented at ... that its urine-based Precision Cancer Monitoring ℠ ... and monitoring of EGFR T790M mutations ... Detection of EGFR T790M Mutation in Urinary ...
(Date:4/17/2015)... 17, 2015 Research and Markets ( ... "Medical Oxygen Systems - Global Strategic Business Report" ... the worldwide markets for Medical Oxygen Systems in US$ ... Systems, Oxygen Cylinders & Regulators, and Oxygen Conserving Devices. ... Canada , Japan ...
Breaking Medicine Technology:Medical Equipment Rental and Leasing Market 2015-2020 - Global Strategic Business Report - Healthcare Spending Slowdown Bodes Well for Medical Equipment Leasing 2Trovagene's Urinary ctDNA Assay Outperforms Tissue Biopsy in Clinical Study for the Detection of EGFR T790M Mutations in Metastatic Lung Cancer Patients 2Trovagene's Urinary ctDNA Assay Outperforms Tissue Biopsy in Clinical Study for the Detection of EGFR T790M Mutations in Metastatic Lung Cancer Patients 3Trovagene's Urinary ctDNA Assay Outperforms Tissue Biopsy in Clinical Study for the Detection of EGFR T790M Mutations in Metastatic Lung Cancer Patients 4Medical Oxygen Systems - 2015 Global Strategic Business Report Featuring Leading Players, Caire, Invacare & Philips Respironics 2
... Care Pharmacy Alliance,s (LTCPA) recent study, "Measurement of Unused ... has been published in the September 2011 issue of ... American Society of Consultant Pharmacists. This is the first ... value of unused solid oral dosage from prescription drugs ...
... RIDGEFIELD, Conn. and INDIANAPOLIS, Sept. 7, 2011 ... LLY ) will present the latest ... Annual Meeting of the European Association for the ... 12-16. Study results evaluating the dipeptidyl peptidase-4 (DPP-4) ...
Cached Medicine Technology:LTCPA Study Quantifying Unused Medicare Part D Drugs in Skilled Nursing Facilities Published in The Consultant Pharmacist 2Boehringer Ingelheim and Lilly to Feature Type 2 Diabetes Research in Presentations at the 47th Annual Meeting of the European Association for the Study of Diabetes 2Boehringer Ingelheim and Lilly to Feature Type 2 Diabetes Research in Presentations at the 47th Annual Meeting of the European Association for the Study of Diabetes 3Boehringer Ingelheim and Lilly to Feature Type 2 Diabetes Research in Presentations at the 47th Annual Meeting of the European Association for the Study of Diabetes 4Boehringer Ingelheim and Lilly to Feature Type 2 Diabetes Research in Presentations at the 47th Annual Meeting of the European Association for the Study of Diabetes 5Boehringer Ingelheim and Lilly to Feature Type 2 Diabetes Research in Presentations at the 47th Annual Meeting of the European Association for the Study of Diabetes 6
(Date:4/18/2015)... 18, 2015 In the past few ... of changes. , "We had to run maintenance on ... changes," said Jennifer Ramirez, the PR Director. "It disrupted ... say that we are back on track after having ... process of changing phone systems which has not allowed ...
(Date:4/18/2015)... York, NY (PRWEB) April 18, 2015 On ... Internal Security Threat Report , which they say, “exposes a ... how many new malware variants were introduced in 2014 - ... took for Zero Day threats to be identified and patched ... it is abundantly clear that doing business in a digital ...
(Date:4/18/2015)... “ ArcAngel ” was featured on NewsWatch ... at the latest and coolest applications on the ... of AppWatch and technology expert, conducted the app review and ... , In a turbulent world, people may find themselves ... always be their first move, but some situations can be ...
(Date:4/18/2015)... 2015 French physician and gastronome Anthelme ... when he uttered, “Tell me what you eat, and ... to cope with stress or sadness has often been ... indicates otherwise. Data collected from their Emotional Eating ... emotional eating, but for different reasons. , Collecting data ...
(Date:4/17/2015)... (PRWEB) April 17, 2015 John Evans, ... Party on the Patio from 2 p.m. to 3 ... located at 1320 Executive Ct. in Pekin, Illinois, serves ... who need some help to maintain their independence. , ... and tropical treats will be served during the luau. ...
Breaking Medicine News(10 mins):Health News:TheBeautyPlace.com Temporary Number Available 2Health News:Cyber Attackers Continue to Fine Tune Deception and Stealth Tactics According to New Report 2Health News:Cyber Attackers Continue to Fine Tune Deception and Stealth Tactics According to New Report 3Health News:Cyber Attackers Continue to Fine Tune Deception and Stealth Tactics According to New Report 4Health News:Cyber Attackers Continue to Fine Tune Deception and Stealth Tactics According to New Report 5Health News:A Personal Safety Application was Featured on NewsWatch Television 2Health News:It’s Not Just A Girl Thing: Queendom Study Reveals That Men Struggle With Emotional Eating Too 2Health News:It’s Not Just A Girl Thing: Queendom Study Reveals That Men Struggle With Emotional Eating Too 3Health News:It’s Not Just A Girl Thing: Queendom Study Reveals That Men Struggle With Emotional Eating Too 4Health News:It’s Not Just A Girl Thing: Queendom Study Reveals That Men Struggle With Emotional Eating Too 5Health News:It’s Not Just A Girl Thing: Queendom Study Reveals That Men Struggle With Emotional Eating Too 6Health News:John Evans Supportive Living Community Prepares for Party on the Patio 2
... February 20, at 10:00 a.m. ESTLA JOLLA, Calif., ... Board: CDXP) will host a teleconference on Friday, ... a fourth quarter business review and drug development ... M.D., M.B.A., will give the presentation and there ...
... language to do numbers, researcher explains , , FRIDAY, Feb. ... basic math and pre-verbal "number sense," but it,s the ... to take math to much higher levels, says a ... of psychology and neuroscience at Duke, studies how human ...
... Healthcare Associates,LLC, the Oregon-based obstetrics, gynecology, midwifery, maternal ... Welch, CNM, MSN, has,been honored by the American ... , Ms. Welch, who ... in Portland, received the honor in a recent ...
... Feb. 13 As the FDA and pharmaceutical ... and mitigation plans for extended release opioids, thousands ... have already discovered a resource that supports the ... Emerging Solutions in Pain ( www.emergingsolutionsinpain.com ) ...
... The following is from Betsy McCaughey, Ph.D., the author ... Obama Stimulus Plan."If Keith Olbermann of MSNBC could ... their merits, he wouldn,t be resorting to personal attacks on ... drug industry (2-12-2009). That,s not true.I am not paid ...
... highest ionized serum calcium 3 times more likely to die, ... A newly identified biomarker for fatal prostate cancer may help ... treatment for the disease. , Men whose levels of ... times more likely to die of prostate cancer than those ...
Cached Medicine News:Health News:Cordex Pharma Sets Fourth Quarter 2008 Program Update Call 2Health News:Cordex Pharma Sets Fourth Quarter 2008 Program Update Call 3Health News:College Kids and Monkeys About Equal on Math 2Health News:Women's Healthcare Associates Midwife Winner of American Academy of Nurse Practitioners State Award of Excellence 2Health News:Opioid Safety and Efficacy Web Resource for Clinicians Supports Education and Practice Needs 2Health News:Opioid Safety and Efficacy Web Resource for Clinicians Supports Education and Practice Needs 3Health News:Invitation to Keith Olbermann 2Health News:Researchers ID Biomarker for Fatal Prostate Cancer 2
... German Craftsmanship have produced the ... world. Ocutek now makes them ... of the coveted Meisterbrief certificate, ... are qualified to become Ocutek ...
... Central platform with integrated neck. ... platform utilizing an internal spring to ... use. Cutting Block fits into precision ... trephine blades sized 6.25 - 9.0mm. ...
Adjustable piston accommodates 7-9mm trephine blade. Complete punch includes base plate, piston carrier, piston for 7 - 9mm trephine blades and 18mm diameter Teflon block. Designed for accurate donor...
... Centuries of German Craftsmanship ... surgical instrumentation in the ... them available to you! ... coveted Meisterbrief certificate, which ...
Medicine Products: